$651 Business Class Flight Deals from Santiago to Detroit

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Stops

Up to 1 stop
$1359
Up to 2 stops
$1363

Airlines

American Airlines
$1359

Cabin Class

First
$1359
Business
$1363

Departure Airports

Cibao International Airport
$1359

Arrival Airports

Detroit Metropolitan Airport
$1359

Layover Airports

Charlotte Douglas International Airport
$1363
Miami International Airport
$1359
Philadelphia International Airport
$1363
Reagan Washington National Airport
$1453

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BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

American Airlines

07/22/25

7:04am

STI

16h 11m

MIA

07/22/25

11:15pm

DTW

American Airlines

07/29/25

6:15am

DTW

15h 4m

MIA

07/29/25

9:19pm

STI

^$1359

American Airlines

07/22/25

7:04am

STI

16h 3m

MIA

PHL

07/22/25

11:07pm

DTW

American Airlines

07/29/25

6:15am

DTW

15h 4m

MIA

07/29/25

9:19pm

STI

^$1363

American Airlines

07/22/25

7:04am

STI

16h 3m

MIA

PHL

07/22/25

11:07pm

DTW

American Airlines

07/29/25

7:31pm

DTW

25h 48m

CLT

MIA

07/30/25

9:19pm

STI

^$1363

American Airlines

07/22/25

7:04am

STI

16h 11m

MIA

07/22/25

11:15pm

DTW

American Airlines

07/29/25

7:31pm

DTW

25h 48m

CLT

MIA

07/30/25

9:19pm

STI

^$1363

American Airlines

07/22/25

1:30pm

STI

9h 45m

MIA

07/22/25

11:15pm

DTW

American Airlines

07/29/25

6:15am

DTW

15h 4m

MIA

07/29/25

9:19pm

STI

^$1448

American Airlines

07/22/25

1:30pm

STI

19h 42m

MIA

CLT

07/23/25

9:12am

DTW

American Airlines

07/29/25

6:15am

DTW

15h 4m

MIA

07/29/25

9:19pm

STI

^$1453

American Airlines

07/22/25

7:04am

STI

16h 53m

MIA

DCA

07/22/25

11:57pm

DTW

American Airlines

07/29/25

6:15am

DTW

15h 4m

MIA

07/29/25

9:19pm

STI

^$1453

American Airlines

07/22/25

1:30pm

STI

9h 5m

MIA

CLT

07/22/25

10:35pm

DTW

American Airlines

07/29/25

7:31pm

DTW

25h 48m

CLT

MIA

07/30/25

9:19pm

STI

^$1453

American Airlines

07/22/25

1:30pm

STI

11h 14m

MIA

CLT

07/23/25

12:44am

DTW

American Airlines

07/29/25

6:15am

DTW

15h 4m

MIA

07/29/25

9:19pm

STI

^$1453

American Airlines

07/22/25

1:30pm

STI

9h 5m

MIA

CLT

07/22/25

10:35pm

DTW

American Airlines

07/29/25

6:15am

DTW

15h 4m

MIA

07/29/25

9:19pm

STI

^$1453

American Airlines

07/22/25

1:30pm

STI

19h 39m

MIA

DCA

07/23/25

9:09am

DTW

American Airlines

07/29/25

6:15am

DTW

15h 4m

MIA

07/29/25

9:19pm

STI

^$1453

American Airlines

07/22/25

7:04am

STI

16h 11m

MIA

07/22/25

11:15pm

DTW

American Airlines

07/29/25

9:39am

DTW

11h 40m

DCA

MIA

07/29/25

9:19pm

STI

^$1513

American Airlines

07/22/25

7:04am

STI

16h 3m

MIA

PHL

07/22/25

11:07pm

DTW

American Airlines

07/29/25

9:39am

DTW

11h 40m

DCA

MIA

07/29/25

9:19pm

STI

^$1513

American Airlines

07/22/25

7:04am

STI

16h 3m

MIA

PHL

07/22/25

11:07pm

DTW

American Airlines

07/29/25

7:15am

DTW

14h 4m

CLT

MIA

07/29/25

9:19pm

STI

^$1513

American Airlines

07/22/25

1:30pm

STI

10h 27m

MIA

DCA

07/22/25

11:57pm

DTW

American Airlines

07/29/25

6:15am

DTW

15h 4m

MIA

07/29/25

9:19pm

STI

^$1579

American Airlines

07/22/25

1:30pm

STI

11h 14m

MIA

CLT

07/23/25

12:44am

DTW

American Airlines

07/29/25

9:39am

DTW

11h 40m

DCA

MIA

07/29/25

9:19pm

STI

^$1603

American Airlines

07/22/25

1:30pm

STI

9h 45m

MIA

07/22/25

11:15pm

DTW

American Airlines

07/29/25

9:39am

DTW

11h 40m

DCA

MIA

07/29/25

9:19pm

STI

^$1603

American Airlines

07/22/25

7:04am

STI

16h 11m

MIA

07/22/25

11:15pm

DTW

American Airlines

07/29/25

6:15am

DTW

6h 14m

MIA

07/29/25

12:29pm

STI

^$1607

American Airlines

07/22/25

7:04am

STI

16h 3m

MIA

PHL

07/22/25

11:07pm

DTW

American Airlines

07/29/25

6:15am

DTW

6h 14m

MIA

07/29/25

12:29pm

STI

^$1612

American Airlines

07/22/25

1:30pm

STI

9h 45m

MIA

07/22/25

11:15pm

DTW

American Airlines

07/29/25

6:15am

DTW

6h 14m

MIA

07/29/25

12:29pm

STI

^$1697

Top Deals on flights Business Class from Santiago to Detroit

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

7:04am

STI

16h 11m

MIA

Jul 24

11:15pm

DTW

as low as

^$651

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

1:30pm

STI

9h 45m

MIA

Jul 24

11:15pm

DTW

as low as

^$728

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

1:30pm

STI

11h 14m

MIA

CLT

Jul 25

12:44am

DTW

as low as

^$732

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

7:04am

STI

16h 53m

MIA

DCA

Jul 24

11:57pm

DTW

as low as

^$738

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

1:30pm

STI

19h 39m

MIA

DCA

Jul 25

9:09am

DTW

as low as

^$738

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

7:04am

STI

26h 5m

MIA

DCA

Jul 25

9:09am

DTW

as low as

^$773

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

1:30pm

STI

10h 27m

MIA

DCA

Jul 24

11:57pm

DTW

as low as

^$820

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

1:30pm

STI

9h 6m

MIA

CLT

Jul 24

10:36pm

DTW

as low as

^$820

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

1:30pm

STI

19h 45m

MIA

CLT

Jul 25

9:15am

DTW

as low as

^$825

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

7:04am

STI

11h 40m

MIA

CLT

Jul 24

6:44pm

DTW

as low as

^$892

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

7:04am

STI

14h 41m

MIA

ORD

Jul 24

9:45pm

DTW

as low as

^$1036

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines

Jul 24

7:04am

STI

13h 18m

MIA

ORD

Jul 24

8:22pm

DTW

as low as

^$1036

Frequently Asked Questions

What are the most convenient layover airports for the flight?

Convenient layover airports for your flight from Santiago to Detroit include Miami International Airport, Charlotte Douglas International Airport, and Philadelphia International Airport, all serviced by American Airlines.

What are the cheapest and fastest flight options from Santiago to Detroit?

The cheapest flight is with American Airlines at $1359, taking 16 hours 11 minutes. The fastest flight is also with American Airlines at $1453, taking 9 hours 5 minutes.

What are all possible destination arrival airports?

The possible destination arrival airports are Detroit Metropolitan Airport, Miami International Airport, Charlotte Douglas International Airport, and Philadelphia International Airport.

What is the time difference between destination and arrival?

The time difference between Santiago and Detroit is typically 1 hour, with Detroit being ahead. However, please confirm the current local times during your travel dates.

Is there a direct flight from Santiago to Detroit?

There is no direct flight from Santiago to Detroit. The cheapest available flight is with American Airlines, priced at $1359, with one stop at Miami International Airport.

Are there convenient layover flights from Santiago to Detroit?

Yes, convenient layover flights from Cibao International Airport to Detroit Metropolitan Airport include a 1 stop flight with American Airlines for $1359, and a 2 stops flight with American Airlines for $1363.