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Flight Deals from Santiago to Detroit from $218

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Stops

  • Up to 1 stop
    $415
  • Up to 2 stops
    $708

Airlines

  • American Airlines
    $901
  • JetBlue
    $706
  • Spirit Airlines
    $415
  • United Airlines
    $747

Cabin Class

  • Economy
    $415

Departure Airports

  • Cibao International Airport
    $415

Arrival Airports

  • Detroit Metropolitan Airport
    $415

Layover Airports

  • Charlotte Douglas International Airport
    $901
  • Chicago O Hare Airport
    $866
  • Fort Lauderdale Hollywood International Airport
    $415
  • General Edward Lawrence Logan International Airport
    $768
  • Miami International Airport
    $901
  • New York John F Kennedy Airport
    $706
  • Newark Liberty Airport
    $747
  • Orlando International Airport
    $708

Best Price. GUARANTEED.

Exclusively for Priceline Members
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Spirit Airlines Logo
Spirit Airlines

07/24/25

STI
13h 33m
FLL

07/25/25

DTW
Spirit Airlines Logo
Spirit Airlines

07/31/25

DTW
16h 24m
FLL

08/01/25

STI
$415
Spirit Airlines Logo
Spirit Airlines

07/24/25

STI
23h 28m
FLL

07/25/25

DTW
Spirit Airlines Logo
Spirit Airlines

07/31/25

DTW
16h 24m
FLL

08/01/25

STI
$423
Spirit Airlines Logo
Spirit Airlines

07/24/25

STI
13h 33m
FLL

07/25/25

DTW
Spirit Airlines Logo
Spirit Airlines

07/31/25

DTW
25h 12m
FLL

08/01/25

STI
$423
Spirit Airlines Logo
Spirit Airlines

07/24/25

STI
13h 33m
FLL

07/25/25

DTW
Spirit Airlines Logo
Spirit Airlines

07/31/25

DTW
27h 20m
FLL

08/01/25

STI
$423
Spirit Airlines Logo
Spirit Airlines

07/24/25

STI
23h 28m
FLL

07/25/25

DTW
Spirit Airlines Logo
Spirit Airlines

07/31/25

DTW
27h 20m
FLL

08/01/25

STI
$432
Spirit Airlines Logo
Spirit Airlines

07/24/25

STI
23h 28m
FLL

07/25/25

DTW
Spirit Airlines Logo
Spirit Airlines

07/31/25

DTW
25h 12m
FLL

08/01/25

STI
$432
JetBlue Logo
JetBlue

07/24/25

STI
27h
JFK

07/25/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
7h 43m
JFK

07/31/25

STI
$706
JetBlue Logo
JetBlue

07/24/25

STI
25h 21m
JFK

07/25/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
7h 43m
JFK

07/31/25

STI
$706
JetBlue Logo
JetBlue

07/24/25

STI
27h
JFK

07/25/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
16h 9m
JFK
MCO

07/31/25

STI
$708
JetBlue Logo
JetBlue

07/24/25

STI
25h 21m
JFK

07/25/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
16h 9m
JFK
MCO

07/31/25

STI
$708
JetBlue Logo
JetBlue

07/24/25

STI
25h 21m
JFK

07/25/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
15h 13m
JFK

07/31/25

STI
$718
JetBlue Logo
JetBlue

07/24/25

STI
25h 21m
JFK

07/25/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
13h 34m
JFK

07/31/25

STI
$718
JetBlue Logo
JetBlue

07/24/25

STI
18h 58m
JFK

07/24/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
16h 9m
JFK
MCO

07/31/25

STI
$734
United Airlines Logo
United Airlines

07/24/25

STI
17h 10m
EWR

07/24/25

DTW
United Airlines Logo
United Airlines

07/31/25

DTW
18h 46m
EWR

08/01/25

STI
$747
United Airlines Logo
United Airlines

07/24/25

STI
9h 3m
EWR

07/24/25

DTW
United Airlines Logo
United Airlines

07/31/25

DTW
18h 46m
EWR

08/01/25

STI
$747
JetBlue Logo
JetBlue

07/24/25

STI
9h 10m
JFK

07/24/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
16h 9m
JFK
MCO

07/31/25

STI
$756
JetBlue Logo
JetBlue

07/24/25

STI
13h 51m
JFK
BOS

07/24/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
16h 9m
JFK
MCO

07/31/25

STI
$768
JetBlue Logo
JetBlue

07/24/25

STI
13h 51m
JFK
BOS

07/24/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
7h 43m
JFK

07/31/25

STI
$769
JetBlue Logo
JetBlue

07/24/25

STI
9h 10m
JFK

07/24/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
27h 2m
JFK
MCO

08/01/25

STI
$777
JetBlue Logo
JetBlue

07/24/25

STI
13h 51m
JFK
BOS

07/24/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
13h 34m
JFK

07/31/25

STI
$781
JetBlue Logo
JetBlue

07/24/25

STI
13h 51m
JFK
BOS

07/24/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
15h 13m
JFK

07/31/25

STI
$781
JetBlue Logo
JetBlue

07/24/25

STI
29h 36m
JFK
BOS

07/25/25

DTW
JetBlue Logo
JetBlue

07/31/25

DTW
7h 43m
JFK

07/31/25

STI
$789
United Airlines Logo
United Airlines

07/24/25

STI
9h 3m
EWR

07/24/25

DTW
United Airlines Logo
United Airlines

07/31/25

DTW
16h 1m
EWR

08/01/25

STI
$862
United Airlines Logo
United Airlines

07/24/25

STI
17h 10m
EWR

07/24/25

DTW
United Airlines Logo
United Airlines

07/31/25

DTW
16h 1m
EWR

08/01/25

STI
$862
United Airlines Logo
United Airlines

07/24/25

STI
17h 10m
EWR

07/24/25

DTW
United Airlines Logo
United Airlines

07/31/25

DTW
19h 46m
ORD
EWR

08/01/25

STI
$866
United Airlines Logo
United Airlines

07/24/25

STI
9h 3m
EWR

07/24/25

DTW
United Airlines Logo
United Airlines

07/31/25

DTW
19h 46m
ORD
EWR

08/01/25

STI
$866
American Airlines Logo
American Airlines

07/24/25

STI
15h 32m
MIA
CLT

07/24/25

DTW
American Airlines Logo
American Airlines

07/31/25

DTW
25h 48m
CLT
MIA

08/01/25

STI
$901
American Airlines Logo
American Airlines

07/24/25

STI
11h 40m
MIA
CLT

07/24/25

DTW
American Airlines Logo
American Airlines

07/31/25

DTW
25h 48m
CLT
MIA

08/01/25

STI
$901
American Airlines Logo
American Airlines

07/24/25

STI
16h 11m
MIA

07/24/25

DTW
American Airlines Logo
American Airlines

07/31/25

DTW
30h 16m
CLT
MIA

08/01/25

STI
$901
American Airlines Logo
American Airlines

07/24/25

STI
16h 11m
MIA

07/24/25

DTW
American Airlines Logo
American Airlines

07/31/25

DTW
25h 48m
CLT
MIA

08/01/25

STI
$901

Top Deals on flights from Santiago to Detroit

Santiago, DO (STI) - Detroit, US (DTT)

Spirit Airlines Logo
Spirit Airlines

Jul 24

STI
13h 33m
FLL

Jul 25

DTW

as low as

$218

Santiago, DO (STI) - Detroit, US (DTT)

Spirit Airlines Logo
Spirit Airlines

Jul 24

STI
23h 28m
FLL

Jul 25

DTW

as low as

$227

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Jul 24

STI
29h 25m
MIA
PHL

Jul 25

DTW

as low as

$335

Santiago, DO (STI) - Detroit, US (DTT)

JetBlue Logo
JetBlue

Jul 24

STI
25h 21m
JFK

Jul 25

DTW

as low as

$357

Santiago, DO (STI) - Detroit, US (DTT)

JetBlue Logo
JetBlue

Jul 24

STI
27h
JFK

Jul 25

DTW

as low as

$357

Santiago, DO (STI) - Detroit, US (DTT)

JetBlue Logo
JetBlue

Jul 24

STI
24h 19m
JFK
BOS

Jul 25

DTW

as low as

$455

Santiago, DO (STI) - Detroit, US (DTT)

JetBlue Logo
JetBlue

Jul 24

STI
13h 51m
JFK
BOS

Jul 24

DTW

as low as

$455

Santiago, DO (STI) - Detroit, US (DTT)

JetBlue Logo
JetBlue

Jul 24

STI
30h 44m
SJU
JFK

Jul 25

DTW

as low as

$461

Santiago, DO (STI) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 24

STI
9h 3m
EWR

Jul 24

DTW

as low as

$464

Santiago, DO (STI) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 24

STI
17h 10m
EWR

Jul 24

DTW

as low as

$464

Santiago, DO (STI) - Detroit, US (DTT)

JetBlue Logo
JetBlue

Jul 24

STI
40h 19m
MCO
JFK

Jul 25

DTW

as low as

$511

Santiago, DO (STI) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Jul 24

STI
16h 11m
MIA

Jul 24

DTW

as low as

$527

Frequently Asked Questions

Is there a direct flight from Santiago to Detroit?
There is no direct flight from Santiago to Detroit. The available options include one-stop flights with Spirit Airlines at $415, United Airlines at $747, JetBlue at $706, and American Airlines at $901, all with varying layover times.
Are there convenient layover flights from Santiago to Detroit?
Yes, there are convenient layover flights available. Airlines include Spirit Airlines: $415, United Airlines: $747, JetBlue: $706, and American Airlines: $901 for 1 stop flights. For 2 stops, options are JetBlue: $768 and American Airlines: $901.
What are the most convenient layover airports for my flight?
For your flight from Santiago to Detroit, convenient layover airports are Fort Lauderdale Hollywood International Airport (Spirit), Newark Liberty Airport (United), New York John F Kennedy Airport (JetBlue), and Miami International Airport (American Airlines).
What is the cheapest and fastest flight from Santiago to Detroit?
The cheapest flight is with Spirit Airlines for $415, taking 13 hours 33 minutes. The fastest is with United Airlines for $747, taking 9 hours 3 minutes.
What are all possible destination arrival airports?
The possible destination arrival airport is Detroit Metropolitan Airport. Layover airports include Fort Lauderdale Hollywood International Airport, Newark Liberty Airport, New York John F Kennedy Airport, Miami International Airport, and Charlotte Douglas International Airport.
What is the time difference between destination and arrival?
The time difference between Santiago and Detroit is typically 1 hour, with Santiago usually ahead. Please confirm local times before travel as they can vary with daylight saving changes.
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