3 Star Hotel

Residence Inn by Marriott Jacksonville-Mayo Clinic Area

4905 San Pablo Road South, Jacksonville, FL, United States View Map

Residence Inn by Marriott Jacksonville-Mayo Clinic Area1/44
Residence Inn by Marriott Jacksonville-Mayo Clinic Area photo 2
Residence Inn by Marriott Jacksonville-Mayo Clinic Area photo 3
Residence Inn by Marriott Jacksonville-Mayo Clinic Area photo 4

Residence Inn by Marriott Jacksonville-Mayo Clinic Area

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About

Comfortable Accommodations Residence Inn By Marriott Jacksonville-Mayo Clinic Area in Jacksonville offers family rooms with air-conditioning, private bathrooms, and modern amenities. Each room includes a sofa bed, TV, and kitchenette. Exceptional Facilities Guests enjoy a fitness center, free use of bicycles, terrace, bar, and a year-round outdoor swimming pool. Free WiFi is available throughout the property. Convenient Location Located 0.9 mi from Harbor City Municipal Golf Course and 27 mi from Jacksonville International Airport. Nearby attractions include Jacksonville Beach Golf Club (5 mi) and Beaches Museum & History Park (5 mi). Guest Satisfaction Highly rated for room cleanliness, attentive staff, and convenient location.

290 Reviews

9.3Exceptional
Cleanliness
9.6
Staff
9.2
Location
9.5

What Guests Say

  • “Customer service cleanliness, good food breakfast”
  • “I have to go to Mayo for appointments and this hotel is perfectly located to the clinic and shops for anything needed. Everyone is…”
Show 50 Verified Reviews

Top Amenities

  • Swimming Pool
  • Free Internet Access
  • Free Parking
  • Fitness Center
  • Accessible Rooms / Facilities
  • Pets Allowed
  • Non-Smoking Rooms
Show All Amenities

Room Options

Our Best Price. GUARANTEED.

Exclusively for Priceline members Details

Adjustable Bed, 1 Bedroom Suite, Queen, Sofa Bed1/4

Adjustable Bed, 1 Bedroom Suite, Queen, Sofa Bed

1 Queen, 1 Sofabed

  • Air conditioning
  • Alarm clock
  • Bath or Shower
  • Cleaning products
One-Bedroom Corner Suite with Roll-In Shower - Mobility and Hearing Accessible1/4

One-Bedroom Corner Suite with Roll-In Shower - Mobility and Hearing Accessible

646 sqft • 2 Queen or 1 Sofabed

  • Accessible bath/shower
  • Accessible room
  • Air conditioning
  • Bath or Shower
King Studio Suite with Sofa Bed and Roll-in Shower - Mobility Accessible1/4

King Studio Suite with Sofa Bed and Roll-in Shower - Mobility Accessible

410 sqft • 1 Sofabed, 1 King

  • Accessible bath/shower
  • Accessible room
  • Air conditioning
  • Bath or Shower
Corner King Studio with Sofa Bed - Hearing Accessible1/4

Corner King Studio with Sofa Bed - Hearing Accessible

646 sqft • 1 Sofabed, 1 King

  • Accessible room
  • Air conditioning
  • Bath or Shower
  • Crib(s)
King Studio Suite, Studio, 1 King, Sofa bed1/4

King Studio Suite, Studio, 1 King, Sofa bed

399 sqft • 1 Sofabed, 1 King

  • Accessible bath/shower
  • Accessible toilet
  • Accessible vanities
  • Air conditioning
Queen Queen 1 Bedrm Suite, 1 Bedroom 2 Room Suite, 2 Queen, Sofa Bed1/4

Queen Queen 1 Bedrm Suite, 1 Bedroom 2 Room Suite, 2 Queen, Sofa Bed

539 sqft • 2 Queen, 1 Sofabed

  • Accessible vanities
  • Air conditioning
  • Alarm clock
  • Baby Cot

Room Details and Photos

Room Amenities

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    What Guests Loved

    9.3
    Exceptional

    Based on 290 reviews

    Location

    9.5

    Cleanliness

    9.6

    Staff

    9.2

    Overall Quality

    9.1

    Pros +

    • Customer service cleanliness, good food breakfast
    • I have to go to Mayo for appointments and this hotel is perfectly located to the clinic and shops for anything needed. Everyone is always very nice and the hotel is always quiet and very clean. The rooms are very nice and relaxing.
    • Location to Mayo is great. Also not far from restaurants and shopping center for groceries. Hotel was very clean, as was the room itself. The room was very comfortable and it was great to have the kitchen.

    Cons -

    • Only the location of the tv.
    • It would be nice if breakfast was a more varied on different days and the time extended to 10:00 am.
    • Stayed a week, had been requesting housekeeping since I checked in. After I contacted the gêner manager and Bonvoy I finally received housekeeping after the 3rd day I was there.
    Business Traveler (10)Solo Traveler (21)Traveling as Couple (77)Family with Young Children (77)Group Traveler (5)Total (308)
    10Verified guestPosted on: 8-6-2026

    Customer service cleanliness, good food breakfast

    10Verified guestPosted on: 4-20-2025

    I have to go to Mayo for appointments and this hotel is perfectly located to the clinic and shops for anything needed. Everyone is always very nice and the hotel is always quiet and very clean. The rooms are very nice and relaxing.

    10Verified guestPosted on: 2-11-2025

    Location to Mayo is great. Also not far from restaurants and shopping center for groceries. Hotel was very clean, as was the room itself. The room was very comfortable and it was great to have the kitchen.

    9Verified Hotel GuestPosted on: 2-1-2024

    Clean, quiet, kind staff and a lovely, relaxing room

    9Verified Hotel GuestPosted on: 1-8-2024

    It is a beautiful place! It is also one of the cleanest hotels I have stayed in! The staff was friendly. The only negative is the location of tv. It is so low it is difficult to see it when in bed. It definitely needs to be raised! I would def stay here!

    Only the location of the tv.

    9Verified Hotel GuestPosted on: 10-30-2023

    Including location, room, modernness this is one of the best hotels I've stayed in lately.

    It would be nice if breakfast was a more varied on different days and the time extended to 10:00 am.

    6DerrenPosted on: 7-2-2023

    Hotel itself is updated and convenient location

    Stayed a week, had been requesting housekeeping since I checked in. After I contacted the gêner manager and Bonvoy I finally received housekeeping after the 3rd day I was there.

    9JoycePosted on: 5-5-2022

    Liked wheelchairs available in lobby, shuttle to Mayo Clinic Very clean and attractive , especially our room. Staff was great.

    No complementary coffee in lobby for guests, breakfast was cold and lacking variety.

    9RobertPosted on: 10-23-2021

    spent 3 days here was going to stay one more day but was book up close to mayo clinic which was nice

    10LindaPosted on: 6-5-2025

    Hot varied breakfast selection. Very clean

    7Verified guestPosted on: 7-12-2024

    Location

    I did not stay the 2nd night. I would like a refund

    9MiguelPosted on: 4-18-2023

    Free breakfast. Pool

    10MarlyshyaPosted on: 2-28-2023

    There¿s no specific thing, every was amazing

    Can¿t say there was

    10MaryPosted on: 1-29-2026

    Very Convenient location to Mayo Clinic, a 5 minute drive . New facility, Clean , comfortable, staff friendly and welcoming.

    Need a couple more lights or lamps in the queen suite. Not as well lit as I need to read etc

    10KimberlyPosted on: 1-28-2026

    First and foremost, the staff. They are friendly and accommodating. I like the location close to Mayo. I'm a patient there and the Residence has a community feel to me. The hourly shuttle to and from Mayo is a big draw from me as well. All the rooms have kitchenettes, which I love because I'm a healthy eater and prefer to make my own meals. I use Instacart.

    Nothing, everything was great.

    10Lawrence B.Posted on: 12-28-2025

    Room layout great for personal or business, excellent breakfast options, nice amenities, friendly staff.

    It is a bit pricey if you require an extended stay.

    10LawrencePosted on: 12-28-2025

    Room layout great for personal or business, excellent breakfast options, nice amenities, friendly staff.

    It is a bit pricey if you require an extended stay.

    3NohoraPosted on: 12-22-2025

    Location, the area is really beautiful, and quiet, the hotel is beautiful as well.

    The air conditioning was really noisy, and it wasn’t really in good shape, it didn’t cooldown much, the pillows smelled like dirty hair, they were white, they look clean, but they smell bad.

    10KimberlyPosted on: 12-14-2025

    The staff!!! They are like family. I'm a patient at Mayo Clinic and I love the welcoming environment. The shuttle to and from Mayo is convenient and a big plus. The rooms have kitchenettes so I have a choice to make my own meals or eat at the restaurant.

    Everything was great.

    10DEANNAPosted on: 11-20-2025

    Breakfast was delicious. Real eggs!

    The coffee provided during the day and hot water were only ever warm. Didn't stay hot.

    Amenities & Policies

    Amenities

    Swimming & Soaking

    • Swimming Pool
    • Outdoor pool

    Fitness & Spa

    • Fitness Center

    Media & Technology

    • Free Internet Access

    Transportation

    • Free Parking
    • Accessible parking

    Health & Safety

    • Health Services
    • Hygiene certification

    Accessibility

    • Handicapped Rooms/Facilities
    • Facilities for disabled guests available
    • Wheelchair accessible

    Kid Friendly

    • Family Friendly
    • Kid Friendly

    General

    • Pets Allowed
    • No Smoking Rooms/Facilities
    • Microwave

    Guest policies

    Check-inAfter 4:00 PM
    Check-outBefore 11:00 AM
    InternetFree Wi-Fi is available.
    ParkingFree parking is available.
    Children & Extra BedsChildren of all ages are welcome. Children of age 0 to 2 stay free with cot.
    PetsPets are allowed. Charges may apply.
    Room RatesAll rates displayed are for two guests unless otherwise noted.

    Important info

    Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.

    Location

    Residence Inn by Marriott Jacksonville-Mayo Clinic Area

    4905 San Pablo Road South, Jacksonville, FL

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