
Flight Deals from Knoxville to San Diego from $294
Top flight deals from leading airlines:







... and +100s more
Save up to 50% on select flights with Priceline
Save an average of $240 per person when bundling your flight and hotel together with Priceline
If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference
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Stops
- Up to 1 stop$366
Airlines
- Alaska Airlines$366
- American Airlines$366
- United Airlines$581
Cabin Class
- Economy$366
Departure Airports
- McGhee Tyson Airport$366
Arrival Airports
- San Diego International Airport$366
Layover Airports
- Charlotte Douglas International Airport$468
- Chicago O Hare Airport$366
- Dallas Fort Worth International Airport$366
- Denver International Airport$581
- George Bush Intercontinental Houston Airport$581
- Washington Dulles Airport$581
Best Price. GUARANTEED.
Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

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Top Deals on flights from Knoxville to San Diego
Knoxville, US (TYS) - San Diego, US (SAN)

Oct 1
Oct 1
as low as
$294
Knoxville, US (TYS) - San Diego, US (SAN)

Nov 25
Nov 25
as low as
$294
Knoxville, US (TYS) - San Diego, US (SAN)

Sep 10
Sep 10
as low as
$294
Knoxville, US (TYS) - San Diego, US (SAN)

Sep 16
Sep 16
as low as
$294
Knoxville, US (TYS) - San Diego, US (SAN)

Sep 17
Sep 17
as low as
$294
Knoxville, US (TYS) - San Diego, US (SAN)

Dec 2
Dec 2
as low as
$294
Knoxville, US (TYS) - San Diego, US (SAN)

Sep 9
Sep 9
as low as
$294
Knoxville, US (TYS) - San Diego, US (SAN)

Dec 3
Dec 3
as low as
$294
Knoxville, US (TYS) - San Diego, US (SAN)

Nov 27
Nov 27
as low as
$300
Knoxville, US (TYS) - San Diego, US (SAN)

Nov 7
Nov 7
as low as
$300
Knoxville, US (TYS) - San Diego, US (SAN)

Oct 25
Oct 25
as low as
$300
Knoxville, US (TYS) - San Diego, US (SAN)

Sep 26
Sep 26
as low as
$300
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