
Flight Deals from San Diego to Knoxville from $168
Top flight deals from leading airlines:







... and +100s more
Save up to 50% on select flights with Priceline
Save an average of $240 per person when bundling your flight and hotel together with Priceline
If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference
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Stops
- Up to 2 stops$336
- Up to 1 stop$436
- Up to 3 stops$473
Airlines
- Alaska Airlines$436
- American Airlines$436
- Delta Air Lines$336
- United Airlines$436
Cabin Class
- Economy$336
Departure Airports
- San Diego International Airport$336
Arrival Airports
- McGhee Tyson Airport$336
Layover Airports
- Charlotte Douglas International Airport$640
- Chicago O Hare Airport$436
- Dallas Fort Worth International Airport$436
- Denver International Airport$468
- Detroit Metropolitan Airport$336
- George Bush Intercontinental Houston Airport$533
- Hartsfield Jackson Atlanta International Airport$336
- Los Angeles International Airport$473
- Mc Clellan-Palomar Airport$468
- McGhee Tyson Airport$336
- Minneapolis-St Paul International/Wold-Chamberlain Airport$615
- San Diego International Airport$336
- Seattle Tacoma International Airport$611
Best Price. GUARANTEED.
Exclusively for Priceline Members
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We'll refund the difference if you find a lower price.

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Top Deals on flights from San Diego to Knoxville
San Diego, US (SAN) - Knoxville, US (TYS)

Oct 6
Oct 6
as low as
$168
San Diego, US (SAN) - Knoxville, US (TYS)

Oct 6
Oct 6
as low as
$218
San Diego, US (SAN) - Knoxville, US (TYS)

May 28
May 28
as low as
$218
San Diego, US (SAN) - Knoxville, US (TYS)

Oct 6
Oct 6
as low as
$218
San Diego, US (SAN) - Knoxville, US (TYS)

Oct 6
Oct 6
as low as
$218
San Diego, US (SAN) - Knoxville, US (TYS)

Oct 6
Oct 6
as low as
$218
San Diego, US (SAN) - Knoxville, US (TYS)

Oct 6
Oct 7
as low as
$387
San Diego, US (SAN) - Knoxville, US (TYS)

Oct 1
Oct 1
as low as
$423
Good to Know
Essential information to help you plan your flight from San Diego to Knoxville
Flights to Knoxville
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- North America
- United States
- Tennessee
- Knoxville