$405 Flight Deals from Panama City to San Francisco

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... and +100s more

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Stops

Nonstop
from $540
Up to 1 stop
$544
Up to 2 stops
$670

Airlines

AVIANCA
$827
COPA Airlines
$689
Hahn Air
$915
United Airlines
$540

Cabin Class

Economy
$540

Departure Airports

Tocumen International Airport
$540

Arrival Airports

Norman Y. Mineta San Jose International Airport
$670
San Francisco International Airport
$540

Layover Airports

Denver International Airport
$670
George Bush Intercontinental Houston Airport
$544
Los Angeles International Airport
$861
Monseñor Óscar Arnulfo Romero International Airport
$827
San Diego International Airport
$915

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BUNDLE & SAVE

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On average save $240 per traveler

United Airlines

08/31/25

3:35pm

PTY

7h 35m

Direct

08/31/25

9:10pm

SFO

United Airlines

09/07/25

10:55am

SFO

7h 15m

Direct

09/07/25

8:10pm

PTY

^$540

United Airlines

08/31/25

3:35pm

PTY

7h 35m

Direct

08/31/25

9:10pm

SFO

United Airlines

09/07/25

12:43am

SFO

15h 54m

IAH

09/07/25

6:37pm

PTY

^$544

United Airlines

08/31/25

3:35pm

PTY

7h 35m

Direct

08/31/25

9:10pm

SFO

United Airlines

09/07/25

6:58pm

SFO

17h 16m

IAH

09/08/25

2:14pm

PTY

^$544

United Airlines

08/31/25

3:35pm

PTY

7h 35m

Direct

08/31/25

9:10pm

SFO

United Airlines

09/07/25

11:59pm

SFO

12h 15m

IAH

09/08/25

2:14pm

PTY

^$544

United Airlines

08/31/25

3:35pm

PTY

7h 35m

Direct

08/31/25

9:10pm

SFO

United Airlines

09/07/25

12:43am

SFO

11h 31m

IAH

09/07/25

2:14pm

PTY

^$544

United Airlines

08/31/25

3:35pm

PTY

7h 35m

Direct

08/31/25

9:10pm

SFO

United Airlines

09/07/25

11:59pm

SFO

16h 38m

IAH

09/08/25

6:37pm

PTY

^$544

United Airlines

08/31/25

3:35pm

PTY

7h 35m

Direct

08/31/25

9:10pm

SFO

United Airlines

09/07/25

5:00am

SFO

11h 37m

IAH

09/07/25

6:37pm

PTY

^$544

United Airlines

08/31/25

3:30pm

PTY

20h 21m

IAH

DEN

09/01/25

9:51am

SJC

United Airlines

09/07/25

10:55am

SFO

7h 15m

Direct

09/07/25

8:10pm

PTY

^$670

United Airlines

08/31/25

3:30pm

PTY

20h 21m

IAH

DEN

09/01/25

9:51am

SJC

United Airlines

09/07/25

7:10am

SFO

9h 27m

IAH

09/07/25

6:37pm

PTY

^$674

COPA Airlines

08/31/25

5:50pm

PTY

7h 49m

Direct

08/31/25

11:39pm

SFO

COPA Airlines

09/07/25

1:30am

SFO

7h 11m

Direct

09/07/25

10:41am

PTY

^$689

AVIANCA

08/31/25

3:40pm

PTY

9h 5m

SAL

08/31/25

10:45pm

SFO

AVIANCA

09/07/25

2:20pm

SFO

18h 5m

SAL

09/08/25

10:25am

PTY

^$827

AVIANCA

08/31/25

3:40pm

PTY

9h 5m

SAL

08/31/25

10:45pm

SFO

AVIANCA

09/07/25

2:20pm

SFO

22h 25m

SAL

09/08/25

2:45pm

PTY

^$834

AVIANCA

08/31/25

8:10pm

PTY

18h 25m

SAL

09/01/25

12:35pm

SFO

AVIANCA

09/07/25

2:20pm

SFO

18h 5m

SAL

09/08/25

10:25am

PTY

^$837

AVIANCA

08/31/25

3:40pm

PTY

22h 55m

SAL

09/01/25

12:35pm

SFO

AVIANCA

09/07/25

2:20pm

SFO

18h 5m

SAL

09/08/25

10:25am

PTY

^$844

AVIANCA

08/31/25

8:10pm

PTY

18h 25m

SAL

09/01/25

12:35pm

SFO

AVIANCA

09/07/25

2:20pm

SFO

22h 25m

SAL

09/08/25

2:45pm

PTY

^$844

AVIANCA

08/31/25

8:10pm

PTY

28h 35m

SAL

09/01/25

10:45pm

SFO

AVIANCA

09/07/25

2:20pm

SFO

18h 5m

SAL

09/08/25

10:25am

PTY

^$844

COPA Airlines

08/31/25

7:40am

PTY

18h 19m

LAX

08/31/25

11:59pm

SFO

COPA Airlines

09/07/25

1:30am

SFO

7h 11m

Direct

09/07/25

10:41am

PTY

^$861

COPA Airlines

08/31/25

11:56am

PTY

14h 3m

LAX

08/31/25

11:59pm

SFO

COPA Airlines

09/07/25

1:30am

SFO

7h 11m

Direct

09/07/25

10:41am

PTY

^$877

COPA Airlines

08/31/25

5:50pm

PTY

7h 49m

Direct

08/31/25

11:39pm

SFO

Hawaiian Airlines

09/07/25

6:15am

SJC

21h 10m

SAN

09/08/25

5:25am

PTY

^$915

COPA Airlines

08/31/25

5:50pm

PTY

7h 49m

Direct

08/31/25

11:39pm

SFO

Hawaiian Airlines

09/07/25

10:20am

SJC

17h 5m

SAN

09/08/25

5:25am

PTY

^$919

COPA Airlines

08/31/25

5:50pm

PTY

7h 49m

Direct

08/31/25

11:39pm

SFO

Alaska Airlines

09/07/25

5:50am

SFO

26h 31m

LAX

09/08/25

10:21am

PTY

^$927

COPA Airlines

08/31/25

1:15pm

PTY

11h 23m

SAN

08/31/25

10:38pm

SJC

COPA Airlines

09/07/25

1:30am

SFO

7h 11m

Direct

09/07/25

10:41am

PTY

^$927

COPA Airlines

08/31/25

5:50pm

PTY

7h 49m

Direct

08/31/25

11:39pm

SFO

Alaska Airlines

09/07/25

5:50am

SFO

26h 45m

LAX

09/08/25

10:35am

PTY

^$927

COPA Airlines

08/31/25

5:50pm

PTY

7h 49m

Direct

08/31/25

11:39pm

SFO

Alaska Airlines

09/07/25

5:50am

SFO

22h 47m

LAX

09/08/25

6:37am

PTY

^$943

COPA Airlines

08/31/25

5:50pm

PTY

7h 49m

Direct

08/31/25

11:39pm

SFO

Alaska Airlines

09/07/25

1:00pm

SJC

19h 21m

LAX

09/08/25

10:21am

PTY

^$945

COPA Airlines

08/31/25

1:15pm

PTY

22h 25m

SAN

09/01/25

9:40am

SJC

COPA Airlines

09/07/25

1:30am

SFO

7h 11m

Direct

09/07/25

10:41am

PTY

^$984

AVIANCA

08/31/25

3:40pm

PTY

9h 5m

SAL

08/31/25

10:45pm

SFO

Hawaiian Airlines

09/07/25

6:15am

SJC

21h 10m

SAN

09/08/25

5:25am

PTY

^$1046

AVIANCA

08/31/25

3:40pm

PTY

9h 5m

SAL

08/31/25

10:45pm

SFO

Hawaiian Airlines

09/07/25

10:20am

SJC

17h 5m

SAN

09/08/25

5:25am

PTY

^$1051

COPA Airlines

08/31/25

5:50pm

PTY

7h 49m

Direct

08/31/25

11:39pm

SFO

COPA Airlines

09/07/25

3:45pm

SJC

11h 48m

DEN

09/08/25

5:33am

PTY

^$1090

AVIANCA

08/31/25

3:40pm

PTY

9h 5m

SAL

08/31/25

10:45pm

SFO

COPA Airlines

09/07/25

3:45pm

SJC

11h 48m

DEN

09/08/25

5:33am

PTY

^$1366

Top Deals on flights from Panama City to San Francisco

Panama City, PA (PTY) - San Francisco, US (SFO)

AVIANCA

Oct 1

3:40pm

PTY

7h 5m

SAL

Oct 1

10:45pm

SFO

as low as

^$405

Panama City, PA (PTY) - San Francisco, US (SFO)

AVIANCA

Aug 23

9:55am

PTY

14h

BOG

SAL

Aug 23

11:55pm

SFO

as low as

^$416

Panama City, PA (PTY) - San Francisco, US (SFO)

Alaska Airlines

Aug 27

1:15pm

PTY

10h 44m

SAN

Aug 27

11:59pm

SFO

as low as

^$572

Panama City, PA (PTY) - San Francisco, US (SFO)

COPA Airlines

Nov 5

1:15pm

PTY

8h 46m

SAN

Nov 5

10:01pm

SFO

as low as

^$596

Panama City, PA (PTY) - San Francisco, US (SFO)

Alaska Airlines

Sep 18

7:40am

PTY

16h 19m

LAX

Sep 18

11:59pm

SFO

as low as

^$737

Panama City, PA (PTY) - San Francisco, US (SFO)

Sep 18

11:05am

PTY

27h 25m

FRA

Sep 19

2:30pm

SFO

as low as

^$804

Panama City, PA (PTY) - San Francisco, US (SFO)

Sep 2

3:30pm

PTY

18h 55m

MIA

DFW

Sep 3

10:25am

SFO

as low as

^$807

Panama City, PA (PTY) - San Francisco, US (SFO)

United Airlines

Aug 12

10:00am

PTY

10h 23m

IAH

Aug 12

8:23pm

SFO

as low as

^$831

Panama City, PA (PTY) - San Francisco, US (SFO)

Hahn Air

Aug 19

7:40am

PTY

8h 28m

LAX

Aug 19

4:08pm

SFO

as low as

^$839

Panama City, PA (PTY) - San Francisco, US (SFO)

United Airlines

Jan 1

3:35pm

PTY

4h 54m

Direct

Jan 1

8:29pm

SFO

as low as

^$875

Panama City, PA (PTY) - San Francisco, US (SFO)

Alaska Airlines

Aug 10

12:04pm

PTY

10h 55m

MCO

Aug 10

10:59pm

SFO

as low as

^$991

Panama City, PA (PTY) - San Francisco, US (SFO)

United Airlines

Dec 25

10:00am

PTY

10h 8m

EWR

Dec 25

8:08pm

SFO

as low as

^$1432

Frequently Asked Questions

What is the time difference between Panama City and San Francisco?

The time difference between Panama City and San Francisco is typically 2 hours, with Panama being ahead. However, this may vary depending on daylight saving changes in San Francisco.

Is there a direct flight from Panama City to San Francisco?

Yes, there are direct flights available from Tocumen International Airport to San Francisco International Airport. Airlines include United Airlines at $540, COPA Airlines at $689, and Hahn Air at $915.

Are there convenient layover flights from Panama City to San Francisco?

Yes, there are convenient layover flights from Panama City to San Francisco. Notable options include United Airlines with a 1 stop flight at $631, and a 2 stop flight at $670. Other airlines offering 1 stop flights include AVIANCA at $827 and COPA Airlines at $861.

What are the most convenient layover airports for my flight from Panama City to San Francisco?

The most convenient layover airports for your flight are George Bush Intercontinental, Denver International, and Monseñor Óscar Arnulfo Romero International. These airports are commonly used for layovers on flights operated by United, AVIANCA, and others.

Cheapest and fastest flight from Panama City to San Francisco

The cheapest flight is with United Airlines at $540, non-stop, 7 hours 35 minutes. The fastest option is the same flight. Other airlines include COPA at $689 and Hahn Air at $915.

What are all possible destination arrival airports?

The possible destination arrival airports are San Francisco International Airport and Norman Y. Mineta San Jose International Airport.

Flights to San Francisco

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Flight Deals from Panama City to San Francisco from $405

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights from Panama City to San Francisco

Frequently Asked Questions

Flights to San Francisco