background

Business Class Flight Deals from Panama City to San Francisco from $919

Bundle + Save

Bundle + Save

Top flight deals from leading airlines:

AS LogoAV LogoCM LogoQR LogoSQ LogoNH LogoEK Logo

... and +100s more

Incredible Deals

Save up to 50% on select flights with Priceline

Bundle & Save

Save an average of $240 per person when bundling your flight and hotel together with Priceline

Best Price Guarantee

If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference

Help 24/7

We’re always here for you - reach us 24 hours a day, 7 days a week

Stops

  • Nonstop
    from $3297
  • Up to 1 stop
    $1636

Airlines

  • American Airlines
    $2236
  • AVIANCA
    $1636
  • COPA Airlines
    $3297

Cabin Class

  • Business
    $1636
  • First
    $2236

Departure Airports

  • Tocumen International Airport
    $1636

Arrival Airports

  • Norman Y. Mineta San Jose International Airport
    $4136
  • San Francisco International Airport
    $1636

Layover Airports

  • Los Angeles International Airport
    $4136
  • Miami International Airport
    $2236
  • Monseñor Óscar Arnulfo Romero International Airport
    $1636

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

Phone Banner
Priceline Phone Deals
Book with an agent for great rates!
BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
AVIANCA Logo
AVIANCA

08/15/25

PTY
9h 5m
SAL

08/15/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
8h 20m
SAL

08/22/25

PTY
$1636
AVIANCA Logo
AVIANCA

08/15/25

PTY
9h 5m
SAL

08/15/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
10h 15m
SAL

08/22/25

PTY
$1636
AVIANCA Logo
AVIANCA

08/15/25

PTY
9h 5m
SAL

08/15/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
12h 40m
SAL

08/22/25

PTY
$1636
AVIANCA Logo
AVIANCA

08/15/25

PTY
18h 25m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
8h 20m
SAL

08/22/25

PTY
$1646
AVIANCA Logo
AVIANCA

08/15/25

PTY
18h 25m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
10h 15m
SAL

08/22/25

PTY
$1646
AVIANCA Logo
AVIANCA

08/15/25

PTY
9h 5m
SAL

08/15/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
18h 5m
SAL

08/23/25

PTY
$1646
AVIANCA Logo
AVIANCA

08/15/25

PTY
18h 25m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
12h 40m
SAL

08/22/25

PTY
$1646
AVIANCA Logo
AVIANCA

08/15/25

PTY
28h 35m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
12h 40m
SAL

08/22/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
28h 35m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
8h 20m
SAL

08/22/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
9h 5m
SAL

08/15/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
29h 55m
SAL

08/23/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
22h 55m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
8h 20m
SAL

08/22/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
29h 45m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
10h 15m
SAL

08/22/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
29h 45m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
12h 40m
SAL

08/22/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
9h 5m
SAL

08/15/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
22h 25m
SAL

08/23/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
28h 35m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
10h 15m
SAL

08/22/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
29h 45m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
8h 20m
SAL

08/22/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
22h 55m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
10h 15m
SAL

08/22/25

PTY
$1653
AVIANCA Logo
AVIANCA

08/15/25

PTY
22h 55m
SAL

08/16/25

SFO
AVIANCA Logo
AVIANCA

08/22/25

SFO
12h 40m
SAL

08/22/25

PTY
$1653
American Airlines Logo
American Airlines

08/15/25

PTY
29h 30m
MIA

08/16/25

SFO
American Airlines Logo
American Airlines

08/22/25

SFO
12h 31m
MIA

08/23/25

PTY
$2236
American Airlines Logo
American Airlines

08/15/25

PTY
29h 30m
MIA

08/16/25

SFO
American Airlines Logo
American Airlines

08/22/25

SFO
28h 30m
MIA

08/23/25

PTY
$2291
American Airlines Logo
American Airlines

08/15/25

PTY
21h 45m
MIA

08/16/25

SFO
American Airlines Logo
American Airlines

08/22/25

SFO
12h 31m
MIA

08/23/25

PTY
$2713
American Airlines Logo
American Airlines

08/15/25

PTY
29h 30m
MIA

08/16/25

SFO
American Airlines Logo
American Airlines

08/22/25

SFO
24h 15m
MIA

08/23/25

PTY
$2751
American Airlines Logo
American Airlines

08/15/25

PTY
21h 45m
MIA

08/16/25

SFO
American Airlines Logo
American Airlines

08/22/25

SFO
28h 30m
MIA

08/23/25

PTY
$2768
American Airlines Logo
American Airlines

08/15/25

PTY
21h 45m
MIA

08/16/25

SFO
American Airlines Logo
American Airlines

08/22/25

SFO
24h 15m
MIA

08/23/25

PTY
$3229
COPA Airlines Logo
COPA Airlines

08/15/25

PTY
7h 49m
Direct

08/15/25

SFO
COPA Airlines Logo
COPA Airlines

08/22/25

SFO
7h 11m
Direct

08/22/25

PTY
$3297
COPA Airlines Logo
COPA Airlines

08/15/25

PTY
7h 49m
Direct

08/15/25

SFO
Alaska Airlines Logo
Alaska Airlines

08/22/25

SJC
22h 37m
LAX

08/23/25

PTY
$4136
COPA Airlines Logo
COPA Airlines

08/15/25

PTY
7h 49m
Direct

08/15/25

SFO
Alaska Airlines Logo
Alaska Airlines

08/22/25

SJC
29h 39m
LAX

08/23/25

PTY
$4136
COPA Airlines Logo
COPA Airlines

08/15/25

PTY
7h 49m
Direct

08/15/25

SFO
Alaska Airlines Logo
Alaska Airlines

08/22/25

SJC
12h 33m
LAX

08/23/25

PTY
$4163
COPA Airlines Logo
COPA Airlines

08/15/25

PTY
7h 49m
Direct

08/15/25

SFO
Alaska Airlines Logo
Alaska Airlines

08/22/25

SJC
19h 35m
LAX

08/23/25

PTY
$4163
COPA Airlines Logo
COPA Airlines

08/15/25

PTY
7h 49m
Direct

08/15/25

SFO
Alaska Airlines Logo
Alaska Airlines

08/22/25

SJC
22h
LAX

08/23/25

PTY
$4184

Top Deals on flights Business Class from Panama City to San Francisco

Panama City, PA (PTY) - San Francisco, US (SFO)

AVIANCA Logo
AVIANCA

Aug 15

PTY
9h 5m
SAL

Aug 15

SFO

as low as

$919

Panama City, PA (PTY) - San Francisco, US (SFO)

AVIANCA Logo
AVIANCA

Aug 15

PTY
18h 25m
SAL

Aug 16

SFO

as low as

$929

Panama City, PA (PTY) - San Francisco, US (SFO)

AVIANCA Logo
AVIANCA

Aug 15

PTY
22h 55m
SAL

Aug 16

SFO

as low as

$936

Panama City, PA (PTY) - San Francisco, US (SFO)

AVIANCA Logo
AVIANCA

Aug 15

PTY
28h 35m
SAL

Aug 16

SFO

as low as

$936

Panama City, PA (PTY) - San Francisco, US (SFO)

AVIANCA Logo
AVIANCA

Aug 15

PTY
29h 45m
SAL

Aug 16

SFO

as low as

$936

Panama City, PA (PTY) - San Francisco, US (SFO)

American Airlines Logo
American Airlines

Aug 15

PTY
29h 30m
MIA

Aug 16

SFO

as low as

$1170

Panama City, PA (PTY) - San Francisco, US (SFO)

COPA Airlines Logo
COPA Airlines

Aug 15

PTY
7h 49m
Direct

Aug 15

SFO

as low as

$1558

Panama City, PA (PTY) - San Francisco, US (SFO)

American Airlines Logo
American Airlines

Aug 15

PTY
21h 45m
MIA

Aug 16

SFO

as low as

$1647

Frequently Asked Questions

What is the time difference between destination and arrival?
The time difference between Panama City and San Francisco is 3 hours, with San Francisco being ahead. If you depart from Panama, please adjust your arrival time accordingly.
Is there a direct flight from origin to destination?
Yes, there is a direct flight from Panama City to San Francisco. COPA Airlines offers a non-stop flight at a price of $3297 with a flight time of 7 hours and 49 minutes.
Are there convenient layover flights from Panama City to San Francisco?
Yes, there are convenient layover flights with the following options: AVIANCA at $1636 with a layover in Monseñor Óscar Arnulfo Romero International Airport, and American Airlines at $2236 with a layover in Miami International Airport.
What are the most convenient layover airports for the flight?
Consider layovers at Monseñor Óscar Arnulfo Romero International Airport, Miami International Airport, or other major U.S. hubs for flights with AVIANCA or American Airlines when traveling from Panama City to San Francisco.
What are the cheapest and fastest flights from Panama City to San Francisco?
The cheapest flight is with AVIANCA for $1636, 1 stop, 9 hours 5 minutes. The fastest flight is non-stop with COPA Airlines for $3297, 7 hours 49 minutes.
What are all possible destination arrival airports?
The possible destination arrival airport is San Francisco International Airport (SFO).
Priceline Phone Deals

Book with an agent for great rates!
Call now!

1 (888) 775-6158