
Flight Deals from Detroit to Santiago from $163
Top flight deals from leading airlines:







... and +100s more
Save up to 50% on select flights with Priceline
Save an average of $240 per person when bundling your flight and hotel together with Priceline
If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference
We’re always here for you - reach us 24 hours a day, 7 days a week
Stops
- Up to 1 stop$351
- Up to 2 stops$666
Airlines
- JetBlue$666
- Spirit Airlines$351
- United Airlines$847
Cabin Class
- Economy$351
Departure Airports
- Detroit Metropolitan Airport$351
Arrival Airports
- Cibao International Airport$351
Layover Airports
- Chicago O Hare Airport$851
- Fort Lauderdale Hollywood International Airport$351
- General Edward Lawrence Logan International Airport$666
- New York John F Kennedy Airport$666
- Newark Liberty Airport$847
- Orlando International Airport$666
Best Price. GUARANTEED.
Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

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Top Deals on flights from Detroit to Santiago
Detroit, US (DTT) - Santiago, DO (STI)

Jul 23
Jul 24
as low as
$163
Detroit, US (DTT) - Santiago, DO (STI)

Oct 23
Oct 23
as low as
$253
Detroit, US (DTT) - Santiago, DO (STI)

Oct 23
Oct 24
as low as
$259
Detroit, US (DTT) - Santiago, DO (STI)

Oct 23
Oct 23
as low as
$264
Detroit, US (DTT) - Santiago, DO (STI)

Oct 23
Oct 23
as low as
$265
Detroit, US (DTT) - Santiago, DO (STI)

Jul 23
Jul 24
as low as
$324
Detroit, US (DTT) - Santiago, DO (STI)

Jul 23
Jul 23
as low as
$334
Detroit, US (DTT) - Santiago, DO (STI)

Oct 23
Oct 24
as low as
$360
Detroit, US (DTT) - Santiago, DO (STI)

Jun 25
Jun 26
as low as
$418
Detroit, US (DTT) - Santiago, DO (STI)

Jul 23
Jul 24
as low as
$446
Detroit, US (DTT) - Santiago, DO (STI)

Aug 1
Aug 1
as low as
$450
Detroit, US (DTT) - Santiago, DO (STI)

Aug 1
Aug 1
as low as
$465
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