Mayagueez — flights from Des Moines to Mayagueez

Flight Deals from Des Moines to Mayagueez from $389

Name: Mayaguez Plaza Hotel, BW Signature Collection
Rating: 8.6

Round-tripOne-way

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Round-tripOne-way

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Top flight deals from leading airlines:

+100s more

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Good to Know

Essential information to help you plan your flight from Des Moines to Mayagueez.

Cheapest Flight Round-trip

$651

Cheapest price found on Priceline for this route in the last 16 days. Found 7 days ago.

$363 below the typical $1,014 round-trip on this route.

Outbound · Nov 10

11:22 amDSMDes Moines International Airport

9:42 amMAZEugenio Maria De Hostos Airport

20h 20m · 2 stops via Chicago (ORD), San Juan (SJU)

Return · Nov 17

1:19 pmMAZEugenio Maria De Hostos Airport

10:59 pmDSMDes Moines International Airport

11h 40m · 2 stops via San Juan (SJU), Chicago (ORD)

Cheapest Flight One-way

$389

Lowest one-way price found on Priceline for this route in the last 16 days. Found 19 days ago.

The typical one-way fare on this route is $640.

Outbound · Oct 22

6:14 amDSMDes Moines International Airport

9:42 amMAZEugenio Maria De Hostos Airport

26h 28m · 2 stops via Dallas (DFW), San Juan (SJU)

Fastest Flights

$3,252

Fastest flight found on Priceline for this route in the last 16 days. Found 10 days ago.

Saves 11h 38m of travel time, but costs $2,601 more than the cheapest fare.

Outbound · Nov 2

5:00 amDSMDes Moines International Airport

4:11 pmMAZEugenio Maria De Hostos Airport

9h 11m · 2 stops via Miami (MIA), San Juan (SJU)

Return · Nov 9

1:19 pmMAZEugenio Maria De Hostos Airport

10:30 pmDSMDes Moines International Airport

11h 11m · 2 stops via San Juan (SJU), Houston (IAH)

Good deal price

$811

A round-trip at or under $811 is a good deal on this route right now.

75% of the fares we found on this route cost more; only a quarter cost less.

Best time to fly

Evenings

Evening departures average $860 on this route, the lowest of any time of day.

$158 less than the average departure, which is $1,018.

Priceline Phone Deals

Book with an agent for great rates!

Call now!1 (888) 775-6158

United Airlinesfound Oct 13

11/10/26

11:22 am

DSM

20h 20mORDSJU

11/11/26

9:42 am

MAZ

11/17/26

1:19 pm

MAZ

11h 40mSJUORD

11/17/26

10:59 pm

DSM

^$651

United Airlinesfound Oct 13

11/10/26

9:55 am

DSM

21h 47mORDSJU

11/11/26

9:42 am

MAZ

11/17/26

1:19 pm

MAZ

11h 40mSJUORD

11/17/26

10:59 pm

DSM

^$651

American Airlinesfound Oct 13

11/10/26

11:09 am

DSM

20h 33mCLTSJU

11/11/26

9:42 am

MAZ

11/17/26

1:19 pm

MAZ

12h 7mSJUCLT

11/17/26

11:26 pm

DSM

^$706

United Airlinesfound Oct 13

11/10/26

6:05 am

DSM

10h 38mORDSJU

11/10/26

6:43 pm

MAZ

11/17/26

1:19 pm

MAZ

11h 40mSJUORD

11/17/26

10:59 pm

DSM

^$671

BUNDLE + SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

American Airlinesfound Oct 13

11/10/26

9:37 am

DSM

22h 5mDFWSJU

11/11/26

9:42 am

MAZ

11/17/26

1:19 pm

MAZ

12h 7mSJUCLT

11/17/26

11:26 pm

DSM

^$706

American Airlinesfound Oct 13

11/10/26

8:07 am

DSM

23h 35mCLTSJU

11/11/26

9:42 am

MAZ

11/17/26

1:19 pm

MAZ

12h 7mSJUCLT

11/17/26

11:26 pm

DSM

^$706

United Airlinesfound Oct 13

11/10/26

11:22 am

DSM

20h 20mORDSJU

11/11/26

9:42 am

MAZ

11/17/26

1:19 pm

MAZ

11h 40mSJUORD

11/17/26

10:59 pm

DSM

^$685

American Airlinesfound Oct 13

11/10/26

11:09 am

DSM

23h 35mCLTSJU

11/11/26

12:44 pm

MAZ

11/17/26

1:19 pm

MAZ

12h 7mSJUCLT

11/17/26

11:26 pm

DSM

^$706

United Airlinesfound Oct 13

11/10/26

9:55 am

DSM

21h 47mORDSJU

11/11/26

9:42 am

MAZ

11/17/26

1:19 pm

MAZ

11h 40mSJUORD

11/17/26

10:59 pm

DSM

^$685

American Airlinesfound Oct 13

11/10/26

9:37 am

DSM

25h 7mDFWSJU

11/11/26

12:44 pm

MAZ

11/17/26

1:19 pm

MAZ

12h 7mSJUCLT

11/17/26

11:26 pm

DSM

^$706

Top Deals on flights from Des Moines to Mayagueez

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

American Airlines

Oct 22

6:14 am

DSM

26h 28m2 stops · DFW, SJU

Oct 23

9:42 am

MAZ

Search More

as low as

^$389

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

American Airlines

Oct 22

6:14 am

DSM

29h 30m2 stops · DFW, SJU

Oct 23

12:44 pm

MAZ

Search More

as low as

^$395

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

United Airlines

Oct 22

6:00 am

DSM

10h 43m2 stops · IAH, SJU

Oct 22

5:43 pm

MAZ

Search More

as low as

^$398

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

American Airlines

Oct 22

7:42 pm

DSM

21h 1m2 stops · DFW, SJU

Oct 23

5:43 pm

MAZ

Search More

as low as

^$424

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

United Airlines

Oct 22

6:00 am

DSM

26h 42m2 stops · ORD, SJU

Oct 23

9:42 am

MAZ

Search More

as low as

^$479

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

United Airlines

Oct 22

6:00 am

DSM

29h 44m2 stops · ORD, SJU

Oct 23

12:44 pm

MAZ

Search More

as low as

^$479

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

United Airlines

Oct 22

6:00 am

DSM

10h 43m2 stops · ORD, SJU

Oct 22

5:43 pm

MAZ

Search More

as low as

^$493

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

American Airlines

Oct 22

9:48 am

DSM

22h 54m2 stops · DFW, SJU

Oct 23

9:42 am

MAZ

Search More

as low as

^$634

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

American Airlines

Oct 22

6:05 am

DSM

26h 37m2 stops · PHL, SJU

Oct 23

9:42 am

MAZ

Search More

as low as

^$634

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

American Airlines

Oct 22

7:08 am

DSM

25h 34m2 stops · CLT, SJU

Oct 23

9:42 am

MAZ

Search More

as low as

^$640

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

American Airlines

Oct 22

9:48 am

DSM

25h 56m2 stops · DFW, SJU

Oct 23

12:44 pm

MAZ

Search More

as low as

^$640

Des Moines, US (DSM) - Mayagueez, PR (MAZ)

American Airlines

Oct 22

6:14 am

DSM

26h 28m2 stops · DFW, SJU

Oct 23

9:42 am

MAZ

Search More

as low as

^$640

See all 12 dealsShow fewer deals

Best Mayagueez Hotel + Flight Packages

Des Moines - Mayagueez packages

Holiday Inn Mayaguez & Tropical Casino By IHG

Round-trip flight from Des Moines

DSM to MAZ

Holiday Inn Mayaguez & Tropical Casino By IHG

Mayaguez, 2701 Highway No 2

8.9759 Reviews3.5-Star Hotel

10% Package Savings

^$1,077/person

$2,389 $2,153 total

Incl. Flight + Hotel

Round-trip flight from Des Moines

DSM to MAZ

Mayaguez Resort & Casino

Mayaguez, Ruta 104 Km 0.3 Sector Algarrobo

6.61,506 Reviews3.5-Star Hotel

^$1,295/person

$2,590 total

Incl. Flight + Hotel

Round-trip flight from Des Moines

DSM to MAZ

TRYP by Wyndham Mayaguez

Mayaguez, 11 Calle Santiago Riera Palmer

8.7557 Reviews3-Star Hotel

10% Package Savings

^$932/person

$2,072 $1,864 total

Incl. Flight + Hotel

Mayaguez Plaza Hotel, BW Signature Collection

Round-trip flight from Des Moines

DSM to MAZ

Mayaguez Plaza Hotel, BW Signature Collection

Mayaguez, 70 Calle Mendez Vigo E

8.6669 Reviews3-Star Hotel

4% Package Savings

^$983/person

$2,050 $1,966 total

Incl. Flight + Hotel

Round-trip flight from Des Moines

DSM to MAZ

pineapple hospitality

Mayaguez, Calle Santiago Riera Palmer

9.546 Reviews0-Star Hotel

^$1,076/person

$2,152 total

Incl. Flight + Hotel

5.1 Loft • Lobby • Generator • Parking • 2nd Floor

Round-trip flight from Des Moines

DSM to MAZ

5.1 Loft • Lobby • Generator • Parking • 2nd Floor

Mayaguez, Apt 5.1 53 Calle Salud Sur

91 Reviews0-Star Hotel

^$830/person

$1,660 total

Incl. Flight + Hotel

5.8 Casita Azul • Balcony • Terrace • Urban

Round-trip flight from Des Moines

DSM to MAZ

5.8 Casita Azul • Balcony • Terrace • Urban

Mayaguez, Apt 5.8 53 Calle Salud

92 Reviews0-Star Hotel

^$863/person

$1,725 total

Incl. Flight + Hotel

5.9 Casita Violeta • Balcony • Terrace • Urban

Round-trip flight from Des Moines

DSM to MAZ

5.9 Casita Violeta • Balcony • Terrace • Urban

Mayaguez, Apt 5.9 53 Calle Salud

91 Reviews0-Star Hotel

^$905/person

$1,809 total

Incl. Flight + Hotel

Best Mayagueez Hotel + Flight + Car Packages

Des Moines - Mayagueez packages

Round-trip flight from Des Moines

DSM to MAZ

Mayaguez Plaza Hotel, BW Signature Collection

Mayaguez, 70 Calle Mendez Vigo E

8.6669 Reviews3-Star Hotel

Rental car included

Pick-up in MAZ

4% Package Savings

^$1,027/person

$2,143 $2,053 total

Incl. Flight + Hotel + Car

Round-trip flight from Des Moines

DSM to MAZ

pineapple hospitality

Mayaguez, Calle Santiago Riera Palmer

9.546 Reviews0-Star Hotel

Rental car included

Pick-up in MAZ

^$1,120/person

$2,240 total

Incl. Flight + Hotel + Car

Round-trip flight from Des Moines

DSM to MAZ

5.1 Loft • Lobby • Generator • Parking • 2nd Floor

Mayaguez, Apt 5.1 53 Calle Salud Sur

91 Reviews0-Star Hotel

Rental car included

Pick-up in MAZ

^$874/person

$1,748 total

Incl. Flight + Hotel + Car

Round-trip flight from Des Moines

DSM to MAZ

5.8 Casita Azul • Balcony • Terrace • Urban

Mayaguez, Apt 5.8 53 Calle Salud

92 Reviews0-Star Hotel

Rental car included

Pick-up in MAZ

^$907/person

$1,813 total

Incl. Flight + Hotel + Car

Round-trip flight from Des Moines

DSM to MAZ

5.9 Casita Violeta • Balcony • Terrace • Urban

Mayaguez, Apt 5.9 53 Calle Salud

91 Reviews0-Star Hotel

Rental car included

Pick-up in MAZ

^$948/person

$1,896 total

Incl. Flight + Hotel + Car

Round-trip flight from Des Moines

DSM to MAZ

Holiday Inn Mayaguez & Tropical Casino By IHG

Mayaguez, 2701 Highway No 2

8.9759 Reviews3.5-Star Hotel

Rental car included

Pick-up in MAZ

10% Package Savings

^$1,120/person

$2,482 $2,240 total

Incl. Flight + Hotel + Car

Round-trip flight from Des Moines

DSM to MAZ

Mayaguez Resort & Casino

Mayaguez, Ruta 104 Km 0.3 Sector Algarrobo

6.61,506 Reviews3.5-Star Hotel

Rental car included

Pick-up in MAZ

^$1,339/person

$2,677 total

Incl. Flight + Hotel + Car

Round-trip flight from Des Moines

DSM to MAZ

TRYP by Wyndham Mayaguez

Mayaguez, 11 Calle Santiago Riera Palmer

8.7557 Reviews3-Star Hotel

Rental car included

Pick-up in MAZ

10% Package Savings

^$976/person

$2,163 $1,951 total

Incl. Flight + Hotel + Car

When is the best time of day to fly?

Evening (5pm - 9pm) is the cheapest time of day to fly from Des Moines to Mayagueez. At $860 it is 16% cheaper than the average time. Afternoon (2pm - 5pm) is the most expensive time, 20% above average.

Show the data

When is the best time of day to fly?
Time of day	Average fare
Morning	$976
Afternoon	$1,219
Evening	$860

What do round-trip flights from Des Moines to Mayagueez cost?

Share of fares in each price range.

Show the data

What do round-trip flights from Des Moines to Mayagueez cost?
Price range	Share of fares
$600 to $700	3%
$700 to $800	21%
$800 to $900	11%
$900 to $1,000	12%
$1,000 to $1,100	32%
$1,100 to $1,200	18%
$1,200 and up	3%

Flight Deals from Des Moines to Mayagueez from $389

Good to Know

Top Deals on flights from Des Moines to Mayagueez

Best Mayagueez Hotel + Flight Packages

Best Mayagueez Hotel + Flight + Car Packages

When is the best time of day to fly?

What do round-trip flights from Des Moines to Mayagueez cost?

Flights to Mayagueez