background

Business Class Flight Deals from Knoxville to San Francisco from $877

Bundle + Save

Bundle + Save

Top flight deals from leading airlines:

AS LogoQR LogoSQ LogoNH LogoEK LogoJL LogoTK Logo

... and +100s more

Incredible Deals

Save up to 50% on select flights with Priceline

Bundle & Save

Save an average of $240 per person when bundling your flight and hotel together with Priceline

Best Price Guarantee

If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference

Help 24/7

We’re always here for you - reach us 24 hours a day, 7 days a week

Stops

  • Up to 1 stop
    $1938

Airlines

  • Alaska Airlines
    $1938

Cabin Class

  • First
    $1938

Departure Airports

  • McGhee Tyson Airport
    $1938

Arrival Airports

  • Norman Y. Mineta San Jose International Airport
    $1938

Layover Airports

  • Dallas Fort Worth International Airport
    $1938

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
Alaska Airlines Logo
Alaska Airlines

09/07/25

TYS
7h 28m
DFW

09/07/25

SJC
Alaska Airlines Logo
Alaska Airlines

09/14/25

SJC
7h 2m
DFW

09/14/25

TYS
$1938
Alaska Airlines Logo
Alaska Airlines

09/07/25

TYS
7h 28m
DFW

09/07/25

SJC
Alaska Airlines Logo
Alaska Airlines

09/14/25

SJC
8h 56m
DFW

09/14/25

TYS
$1938
Alaska Airlines Logo
Alaska Airlines

09/07/25

TYS
8h 6m
DFW

09/07/25

SJC
Alaska Airlines Logo
Alaska Airlines

09/14/25

SJC
7h 2m
DFW

09/14/25

TYS
$2038
Alaska Airlines Logo
Alaska Airlines

09/07/25

TYS
9h 58m
DFW

09/07/25

SJC
Alaska Airlines Logo
Alaska Airlines

09/14/25

SJC
7h 2m
DFW

09/14/25

TYS
$2038
Alaska Airlines Logo
Alaska Airlines

09/07/25

TYS
8h 6m
DFW

09/07/25

SJC
Alaska Airlines Logo
Alaska Airlines

09/14/25

SJC
8h 56m
DFW

09/14/25

TYS
$2038
Alaska Airlines Logo
Alaska Airlines

09/07/25

TYS
10h 6m
DFW

09/07/25

SJC
Alaska Airlines Logo
Alaska Airlines

09/14/25

SJC
7h 2m
DFW

09/14/25

TYS
$2038
Alaska Airlines Logo
Alaska Airlines

09/07/25

TYS
9h 58m
DFW

09/07/25

SJC
Alaska Airlines Logo
Alaska Airlines

09/14/25

SJC
8h 56m
DFW

09/14/25

TYS
$2038
Alaska Airlines Logo
Alaska Airlines

09/07/25

TYS
10h 6m
DFW

09/07/25

SJC
Alaska Airlines Logo
Alaska Airlines

09/14/25

SJC
8h 56m
DFW

09/14/25

TYS
$2038

Top Deals on flights Business Class from Knoxville to San Francisco

Knoxville, US (TYS) - , ()

 Logo

Sep 9

TYS
7h 27m
DFW

Sep 9

SFO

as low as

$877

Knoxville, US (TYS) - San Jose, US (SJC)

Alaska Airlines Logo
Alaska Airlines

Sep 9

TYS
7h 31m
DFW

Sep 9

SJC

as low as

$999

Knoxville, US (TYS) - San Jose, US (SJC)

Alaska Airlines Logo
Alaska Airlines

Sep 9

TYS
8h 11m
DFW

Sep 9

SJC

as low as

$999

Knoxville, US (TYS) - San Jose, US (SJC)

Alaska Airlines Logo
Alaska Airlines

Sep 9

TYS
9h 39m
DFW

Sep 9

SJC

as low as

$999

Knoxville, US (TYS) - San Jose, US (SJC)

Alaska Airlines Logo
Alaska Airlines

Sep 9

TYS
10h 1m
DFW

Sep 9

SJC

as low as

$999

Frequently Asked Questions

What are all possible destination arrival airports?
The possible destination arrival airport is Norman Y. Mineta San Jose International Airport.
What is the time difference between Knoxville and San Francisco?
Knoxville is in the Eastern Time Zone, while San Francisco is in the Pacific Time Zone. There is a 3-hour time difference, with San Francisco being 3 hours behind Knoxville.
Is there a direct flight from Knoxville to San Francisco?
There is no direct flight from Knoxville to San Francisco. The cheapest available option is a 1 stop flight with Alaska Airlines at a price of $1938, which includes a layover at Dallas Fort Worth International Airport.
Are there convenient layover flights from Knoxville to San Francisco?
Yes, there is a convenient 1 stop flight from McGhee Tyson Airport to Norman Y. Mineta San Jose International Airport with Alaska Airlines at a price of $1938, including a layover at Dallas Fort Worth International Airport and a flight time of 7 hours 28 minutes.
What are the most convenient layover airports for my flight?
Consider Dallas Fort Worth International Airport as a convenient layover for your flight from Knoxville to San Francisco with Alaska Airlines.
What is the cheapest and fastest flight from Knoxville to San Francisco?
The cheapest flight is with Alaska Airlines for $1938, taking 7 hours 28 minutes. No faster flight is available.