$443 Business Class Flight Deals from Santo Domingo to Buffalo

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Stops

Up to 2 stops
$1308

Airlines

American Airlines
$1308
COPA Airlines
$5067

Cabin Class

Business
$1308
First
$1912

Departure Airports

Las Américas International Airport
$1308

Arrival Airports

Buffalo Niagara International Airport
$1308

Layover Airports

Charlotte Douglas International Airport
$1308
Miami International Airport
$1308
Philadelphia International Airport
$1308
Reagan Washington National Airport
$1308
Tocumen International Airport
$5067
Washington Dulles Airport
$5067

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BUNDLE & SAVE

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On average save $240 per traveler

American Airlines

09/11/25

7:00am

SDQ

16h 55m

MIA

DCA

09/11/25

11:55pm

BUF

American Airlines

09/18/25

1:42pm

BUF

21h 33m

CLT

MIA

09/19/25

11:15am

SDQ

^$1308

American Airlines

09/11/25

2:35pm

SDQ

9h 37m

MIA

CLT

09/12/25

12:12am

BUF

American Airlines

09/18/25

1:42pm

BUF

21h 33m

CLT

MIA

09/19/25

11:15am

SDQ

^$1308

American Airlines

09/11/25

2:35pm

SDQ

19h 12m

MIA

PHL

09/12/25

9:47am

BUF

American Airlines

09/18/25

1:42pm

BUF

21h 33m

CLT

MIA

09/19/25

11:15am

SDQ

^$1308

American Airlines

09/11/25

12:15pm

SDQ

11h 57m

MIA

CLT

09/12/25

12:12am

BUF

American Airlines

09/18/25

1:42pm

BUF

21h 33m

CLT

MIA

09/19/25

11:15am

SDQ

^$1308

American Airlines

09/11/25

4:20pm

SDQ

19h 9m

MIA

DCA

09/12/25

11:29am

BUF

American Airlines

09/18/25

1:42pm

BUF

21h 33m

CLT

MIA

09/19/25

11:15am

SDQ

^$1308

American Airlines

09/11/25

4:20pm

SDQ

19h 50m

MIA

CLT

09/12/25

12:10pm

BUF

American Airlines

09/18/25

1:42pm

BUF

21h 33m

CLT

MIA

09/19/25

11:15am

SDQ

^$1308

American Airlines

09/11/25

7:00am

SDQ

17h 12m

MIA

CLT

09/12/25

12:12am

BUF

American Airlines

09/18/25

1:42pm

BUF

21h 33m

CLT

MIA

09/19/25

11:15am

SDQ

^$1308

American Airlines

09/11/25

12:15pm

SDQ

11h 57m

MIA

CLT

09/12/25

12:12am

BUF

American Airlines

09/18/25

4:27pm

BUF

18h 48m

PHL

MIA

09/19/25

11:15am

SDQ

^$1595

American Airlines

09/11/25

12:15pm

SDQ

11h 57m

MIA

CLT

09/12/25

12:12am

BUF

American Airlines

09/18/25

5:33pm

BUF

17h 42m

DCA

MIA

09/19/25

11:15am

SDQ

^$1595

American Airlines

09/11/25

7:00am

SDQ

16h 55m

MIA

DCA

09/11/25

11:55pm

BUF

American Airlines

09/18/25

7:29pm

BUF

15h 46m

CLT

MIA

09/19/25

11:15am

SDQ

^$1595

American Airlines

09/11/25

2:35pm

SDQ

9h 37m

MIA

CLT

09/12/25

12:12am

BUF

American Airlines

09/18/25

4:27pm

BUF

18h 48m

PHL

MIA

09/19/25

11:15am

SDQ

^$1595

American Airlines

09/11/25

12:15pm

SDQ

11h 57m

MIA

CLT

09/12/25

12:12am

BUF

American Airlines

09/18/25

7:29pm

BUF

15h 46m

CLT

MIA

09/19/25

11:15am

SDQ

^$1595

American Airlines

09/11/25

2:35pm

SDQ

9h 37m

MIA

CLT

09/12/25

12:12am

BUF

American Airlines

09/18/25

5:33pm

BUF

17h 42m

DCA

MIA

09/19/25

11:15am

SDQ

^$1595

American Airlines

09/11/25

12:15pm

SDQ

11h 40m

MIA

DCA

09/11/25

11:55pm

BUF

American Airlines

09/18/25

4:27pm

BUF

18h 48m

PHL

MIA

09/19/25

11:15am

SDQ

^$1912

American Airlines

09/11/25

12:15pm

SDQ

11h 40m

MIA

DCA

09/11/25

11:55pm

BUF

American Airlines

09/18/25

5:33pm

BUF

17h 42m

DCA

MIA

09/19/25

11:15am

SDQ

^$1912

American Airlines

09/11/25

12:15pm

SDQ

11h 40m

MIA

DCA

09/11/25

11:55pm

BUF

American Airlines

09/18/25

7:29pm

BUF

15h 46m

CLT

MIA

09/19/25

11:15am

SDQ

^$1912

COPA Airlines

09/11/25

11:56am

SDQ

21h 49m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

6:00am

BUF

16h 26m

IAD

PTY

09/18/25

10:26pm

SDQ

^$5067

COPA Airlines

09/11/25

6:17pm

SDQ

15h 28m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

8:00pm

BUF

17h 9m

IAD

PTY

09/19/25

1:09pm

SDQ

^$5067

COPA Airlines

09/11/25

6:17pm

SDQ

15h 28m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

8:00pm

BUF

14h 58m

IAD

PTY

09/19/25

10:58am

SDQ

^$5067

COPA Airlines

09/11/25

8:59am

SDQ

24h 46m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

8:00pm

BUF

17h 9m

IAD

PTY

09/19/25

1:09pm

SDQ

^$5067

COPA Airlines

09/11/25

11:56am

SDQ

21h 49m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

8:00pm

BUF

14h 58m

IAD

PTY

09/19/25

10:58am

SDQ

^$5067

COPA Airlines

09/11/25

2:09pm

SDQ

19h 36m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

6:00am

BUF

16h 26m

IAD

PTY

09/18/25

10:26pm

SDQ

^$5067

COPA Airlines

09/11/25

6:17pm

SDQ

15h 28m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

10:30am

BUF

26h 39m

IAD

PTY

09/19/25

1:09pm

SDQ

^$5067

COPA Airlines

09/11/25

2:09pm

SDQ

19h 36m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

8:00pm

BUF

14h 58m

IAD

PTY

09/19/25

10:58am

SDQ

^$5067

COPA Airlines

09/11/25

6:17pm

SDQ

15h 28m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

6:00am

BUF

28h 58m

IAD

PTY

09/19/25

10:58am

SDQ

^$5067

COPA Airlines

09/11/25

2:09pm

SDQ

19h 36m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

10:30am

BUF

24h 28m

IAD

PTY

09/19/25

10:58am

SDQ

^$5067

COPA Airlines

09/11/25

8:59am

SDQ

24h 46m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

8:00pm

BUF

14h 58m

IAD

PTY

09/19/25

10:58am

SDQ

^$5067

COPA Airlines

09/11/25

5:25am

SDQ

28h 20m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

8:00pm

BUF

14h 58m

IAD

PTY

09/19/25

10:58am

SDQ

^$5067

COPA Airlines

09/11/25

6:17pm

SDQ

15h 28m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

10:30am

BUF

24h 28m

IAD

PTY

09/19/25

10:58am

SDQ

^$5067

COPA Airlines

09/11/25

8:59am

SDQ

24h 46m

PTY

IAD

09/12/25

9:45am

BUF

COPA Airlines

09/18/25

6:00am

BUF

16h 26m

IAD

PTY

09/18/25

10:26pm

SDQ

^$5067

Top Deals on flights Business Class from Santo Domingo to Buffalo

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

American Airlines

Sep 13

7:00am

SDQ

10h 21m

MIA

DCA

Sep 13

5:21pm

BUF

as low as

^$443

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

American Airlines

Sep 13

4:20pm

SDQ

17h 27m

MIA

PHL

Sep 14

9:47am

BUF

as low as

^$449

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

American Airlines

Sep 13

4:20pm

SDQ

20h 43m

MIA

PHL

Sep 14

1:03pm

BUF

as low as

^$449

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

American Airlines

Sep 13

7:00am

SDQ

28h 29m

MIA

DCA

Sep 14

11:29am

BUF

as low as

^$472

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

American Airlines

Sep 13

7:00am

SDQ

14h 53m

MIA

CLT

Sep 13

9:53pm

BUF

as low as

^$682

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

American Airlines

Sep 13

4:20pm

SDQ

20h 32m

MIA

CLT

Sep 14

12:52pm

BUF

as low as

^$687

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

American Airlines

Sep 13

4:20pm

SDQ

18h 40m

MIA

CLT

Sep 14

11:00am

BUF

as low as

^$687

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

American Airlines

Sep 13

7:00am

SDQ

28h

MIA

CLT

Sep 14

11:00am

BUF

as low as

^$719

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

COPA Airlines

Sep 13

11:56am

SDQ

21h 50m

PTY

IAD

Sep 14

9:46am

BUF

as low as

^$2545

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

COPA Airlines

Sep 13

8:59am

SDQ

24h 47m

PTY

IAD

Sep 14

9:46am

BUF

as low as

^$2545

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

COPA Airlines

Sep 13

6:17pm

SDQ

15h 29m

PTY

IAD

Sep 14

9:46am

BUF

as low as

^$2545

Santo Domingo, DO (SDQ) - Buffalo, US (BUF)

COPA Airlines

Sep 13

2:09pm

SDQ

19h 37m

PTY

IAD

Sep 14

9:46am

BUF

as low as

^$2545

Frequently Asked Questions

What are all possible destination arrival airports?

The possible destination arrival airport is Buffalo Niagara International Airport, with layovers at Miami International Airport, Reagan Washington National Airport, Charlotte Douglas International Airport, Tocumen International Airport, and Washington Dulles Airport.

What is the time difference between Santo Domingo and Buffalo?

The time difference between Santo Domingo and Buffalo is one hour, with Santo Domingo being one hour ahead of Buffalo.

Is there a direct flight from Santo Domingo to Buffalo?

There is no direct flight from Santo Domingo to Buffalo. The cheapest and fastest available flights have 2 stops, both offered by American Airlines at a price of $1308.

Are there convenient layover flights from Santo Domingo to Buffalo?

Yes, there are convenient layover flights. American Airlines offers a 2-stop flight for $1308 with layovers in Miami and Reagan, taking 16 hours 55 minutes. COPA Airlines also has a 2-stop option priced at $5067 with layovers in Tocumen and Washington, lasting 15 hours 28 minutes.

What are the most convenient layover airports for my flight?

The most convenient layover airports for your flight from Santo Domingo to Buffalo are Miami International Airport, Reagan Washington National Airport, Charlotte Douglas International Airport, Tocumen International Airport, and Washington Dulles Airport.

What is the cheapest and fastest flight from Santo Domingo to Buffalo?

The cheapest and fastest flight is with American Airlines at $1308, featuring 2 stops with layovers at Miami and Charlotte Douglas airports, taking 9 hours 37 minutes.