background

Business Class Flight Deals from San Antonio to Panama City from $421

Bundle + Save

Bundle + Save

Top flight deals from leading airlines:

QR LogoSQ LogoNH LogoEK LogoJL LogoTK LogoAF Logo

... and +100s more

Incredible Deals

Save up to 50% on select flights with Priceline

Bundle & Save

Save an average of $240 per person when bundling your flight and hotel together with Priceline

Best Price Guarantee

If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference

Help 24/7

We’re always here for you - reach us 24 hours a day, 7 days a week

Stops

  • Up to 1 stop
    $1757

Airlines

  • American Airlines
    $1757

Cabin Class

  • Business
    $1757

Departure Airports

  • San Antonio International Airport
    $1757

Arrival Airports

  • Tocumen International Airport
    $1757

Layover Airports

  • Miami International Airport
    $1757

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

Phone Banner
Priceline Phone Deals
Book with an agent for great rates!
BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
American Airlines Logo
American Airlines

08/10/25

SAT
9h 10m
MIA

08/10/25

PTY
American Airlines Logo
American Airlines

08/17/25

PTY
8h 6m
MIA

08/17/25

SAT
$1757

Top Deals on flights Business Class from San Antonio to Panama City

San Antonio, US (SAT) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 11

SAT
9h 30m
DFW
MIA

Aug 11

PTY

as low as

$421

San Antonio, US (SAT) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 11

SAT
9h 10m
MIA

Aug 11

PTY

as low as

$421

San Antonio, US (SAT) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 11

SAT
19h 45m
DFW
MIA

Aug 12

PTY

as low as

$579

San Antonio, US (SAT) - Panama City, PA (PTY)

 Logo

Aug 11

SAT
19h 25m
LAX

Aug 12

PTY

as low as

$7115

San Antonio, US (SAT) - Panama City, PA (PTY)

 Logo

Aug 11

SAT
27h 35m
LAX

Aug 12

PTY

as low as

$7518

Frequently Asked Questions

Are there convenient layover flights from San Antonio to Panama City?
Yes, there is a convenient 1 stop flight from San Antonio International Airport to Tocumen International Airport with American Airlines priced at $1757, including a layover at Miami International Airport and a flight time of 9 hours 10 minutes.
What are the most convenient layover airports for my flight?
The most convenient layover airport for your flight from San Antonio to Panama City is Miami International Airport with American Airlines.
What is the cheapest and fastest flight from San Antonio to Panama City?
The cheapest flight is with American Airlines at $1757, 1 stop, 9 hours 10 minutes. No faster option available.
What are all possible destination arrival airports?
Possible destination arrival airports are Tocumen International Airport in Panama City, along with potential layover airports like Miami International Airport.
What is the time difference between destination and arrival?
The time difference between San Antonio and Panama City is typically one hour, with Panama being one hour ahead. However, this may vary depending on daylight saving changes.
Is there a direct flight from San Antonio to Panama City?
There is no direct flight from San Antonio to Panama City. The cheapest option is a 1 stop flight with American Airlines at a price of $1757, including a layover at Miami International Airport.
Priceline Phone Deals

Book with an agent for great rates!
Call now!

1 (888) 775-6158