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Business Class Flight Deals from Houston to Panama City from $655

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Stops

  • Nonstop
    from $4274
  • Up to 1 stop
    $1092
  • Up to 2 stops
    $1733

Airlines

  • American Airlines
    $1092
  • AVIANCA
    $1733
  • COPA Airlines
    $4274

Cabin Class

  • Business
    $1092

Departure Airports

  • George Bush Intercontinental Houston Airport
    $1092

Arrival Airports

  • Tocumen International Airport
    $1092

Layover Airports

  • El Dorado International Airport
    $1733
  • Fort Lauderdale Hollywood International Airport
    $1733
  • Miami International Airport
    $1092
  • Monseñor Óscar Arnulfo Romero International Airport
    $1733

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On average save $240 per traveler
American Airlines Logo
American Airlines

09/13/25

IAH
8h 56m
MIA

09/13/25

PTY
American Airlines Logo
American Airlines

09/20/25

PTY
8h 25m
MIA

09/20/25

IAH
$1092
American Airlines Logo
American Airlines

09/13/25

IAH
7h 11m
MIA

09/13/25

PTY
American Airlines Logo
American Airlines

09/20/25

PTY
8h 25m
MIA

09/20/25

IAH
$1092
American Airlines Logo
American Airlines

09/13/25

IAH
8h 56m
MIA

09/13/25

PTY
American Airlines Logo
American Airlines

09/20/25

PTY
19h 3m
MIA

09/21/25

IAH
$1114
American Airlines Logo
American Airlines

09/13/25

IAH
7h 11m
MIA

09/13/25

PTY
American Airlines Logo
American Airlines

09/20/25

PTY
19h 3m
MIA

09/21/25

IAH
$1114
American Airlines Logo
American Airlines

09/13/25

IAH
7h 11m
MIA

09/13/25

PTY
American Airlines Logo
American Airlines

09/20/25

PTY
25h 53m
MIA

09/21/25

IAH
$1114
American Airlines Logo
American Airlines

09/13/25

IAH
8h 56m
MIA

09/13/25

PTY
American Airlines Logo
American Airlines

09/20/25

PTY
25h 53m
MIA

09/21/25

IAH
$1114
AVIANCA Logo
AVIANCA

09/13/25

IAH
13h 5m
FLL
BOG

09/13/25

PTY
AVIANCA Logo
AVIANCA

09/20/25

PTY
18h 45m
BOG
SAL

09/21/25

IAH
$1733
AVIANCA Logo
AVIANCA

09/13/25

IAH
16h 5m
FLL
BOG

09/14/25

PTY
AVIANCA Logo
AVIANCA

09/20/25

PTY
14h 5m
BOG
SAL

09/21/25

IAH
$1733
AVIANCA Logo
AVIANCA

09/13/25

IAH
13h 5m
FLL
BOG

09/13/25

PTY
AVIANCA Logo
AVIANCA

09/20/25

PTY
18h 5m
BOG
SAL

09/21/25

IAH
$1733
AVIANCA Logo
AVIANCA

09/13/25

IAH
16h 5m
FLL
BOG

09/14/25

PTY
AVIANCA Logo
AVIANCA

09/20/25

PTY
16h
SAL

09/21/25

IAH
$1733
AVIANCA Logo
AVIANCA

09/13/25

IAH
13h 5m
FLL
BOG

09/13/25

PTY
AVIANCA Logo
AVIANCA

09/20/25

PTY
36h 45m
BOG
SAL

09/21/25

IAH
$1733
AVIANCA Logo
AVIANCA

09/13/25

IAH
13h 5m
FLL
BOG

09/13/25

PTY
AVIANCA Logo
AVIANCA

09/20/25

PTY
16h
SAL

09/21/25

IAH
$1733
AVIANCA Logo
AVIANCA

09/13/25

IAH
16h 5m
FLL
BOG

09/14/25

PTY
AVIANCA Logo
AVIANCA

09/20/25

PTY
36h 45m
BOG
SAL

09/21/25

IAH
$1733
AVIANCA Logo
AVIANCA

09/13/25

IAH
16h 5m
FLL
BOG

09/14/25

PTY
AVIANCA Logo
AVIANCA

09/20/25

PTY
18h 5m
BOG
SAL

09/21/25

IAH
$1733
COPA Airlines Logo
COPA Airlines

09/13/25

IAH
4h 17m
Direct

09/13/25

PTY
COPA Airlines Logo
COPA Airlines

09/20/25

PTY
4h 20m
Direct

09/20/25

IAH
$4274
COPA Airlines Logo
COPA Airlines

09/13/25

IAH
4h 17m
Direct

09/13/25

PTY
COPA Airlines Logo
COPA Airlines

09/20/25

PTY
4h 20m
Direct

09/20/25

IAH
$4274
COPA Airlines Logo
COPA Airlines

09/13/25

IAH
4h 17m
Direct

09/13/25

PTY
COPA Airlines Logo
COPA Airlines

09/20/25

PTY
4h 20m
Direct

09/20/25

IAH
$4274
COPA Airlines Logo
COPA Airlines

09/13/25

IAH
4h 17m
Direct

09/13/25

PTY
COPA Airlines Logo
COPA Airlines

09/20/25

PTY
4h 20m
Direct

09/20/25

IAH
$4274

Top Deals on flights Business Class from Houston to Panama City

Houston, US (HOU) - Panama City, PA (PTY)

 Logo

Sep 15

IAH
16h 29m
MEX

Sep 16

PTY

as low as

$655

Houston, US (HOU) - Panama City, PA (PTY)

 Logo

Sep 15

IAH
23h 49m
MEX

Sep 16

PTY

as low as

$655

Houston, US (HOU) - Panama City, PA (PTY)

AVIANCA Logo
AVIANCA

Sep 15

IAH
16h 45m
SAL

Sep 16

PTY

as low as

$661

Houston, US (HOU) - Panama City, PA (PTY)

AVIANCA Logo
AVIANCA

Sep 15

IAH
20h 20m
SAL

Sep 16

PTY

as low as

$668

Houston, US (HOU) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Sep 15

IAH
8h 56m
MIA

Sep 15

PTY

as low as

$917

Houston, US (HOU) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Sep 15

IAH
7h 11m
MIA

Sep 15

PTY

as low as

$917

Houston, US (HOU) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Sep 15

IAH
18h 41m
MIA

Sep 16

PTY

as low as

$938

Houston, US (HOU) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Sep 15

IAH
25h 50m
MIA

Sep 16

PTY

as low as

$1017

Houston, US (HOU) - Panama City, PA (PTY)

COPA Airlines Logo
COPA Airlines

Sep 15

IAH
4h 17m
Direct

Sep 15

PTY

as low as

$2107

Houston, US (HOU) - Panama City, PA (PTY)

COPA Airlines Logo
COPA Airlines

Sep 15

IAH
4h 17m
Direct

Sep 15

PTY

as low as

$2107

Frequently Asked Questions

What is the time difference between Houston and Panama City?
The time difference between Houston and Panama City is typically one hour, with Panama being one hour ahead of Houston.
Is there a direct flight from Houston to Panama City?
Yes, there is a direct flight from George Bush Intercontinental Houston Airport to Tocumen International Airport with COPA Airlines at a price of $4274, with a flight time of 4 hours 17 minutes.
Are there convenient layover flights from Houston to Panama City?
Yes, there is a convenient 1 stop flight from Houston to Panama City with American Airlines at $1092, with a layover in Miami. Additionally, there is a 2 stops flight with AVIANCA at $1733, with layovers in Fort Lauderdale and El Dorado.
What are the most convenient layover airports for the flight?
For your flight from Houston to Panama City, convenient layover airports include Miami International Airport, Fort Lauderdale Hollywood International Airport, and El Dorado International Airport.
What are the cheapest and fastest flight options from Houston to Panama City?
The cheapest flight is American Airlines for $1092 with 1 stop in Miami and a flight time of 7 hours 11 minutes. The fastest flight is COPA Airlines for $4274, non-stop, taking 4 hours 17 minutes.
What are all possible destination arrival airports?
The possible arrival airports for your flight from Houston to Panama City are Tocumen International Airport, Miami International Airport, Fort Lauderdale Hollywood International Airport, and El Dorado International Airport.
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