$603 Business Class Flight Deals from Denver to Santiago

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... and +100s more

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Stops

Up to 1 stop
$1231
Up to 2 stops
$1048

Airlines

American Airlines
$1048

Cabin Class

First
$1048

Departure Airports

Denver International Airport
$1048

Arrival Airports

Cibao International Airport
$1048

Layover Airports

Charlotte Douglas International Airport
$1048
Dallas Fort Worth International Airport
$1048
Miami International Airport
$1048

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BUNDLE & SAVE

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On average save $240 per traveler

American Airlines

09/10/25

11:57pm

DEN

10h 30m

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

20h 44m

MIA

DFW

09/18/25

8:13am

DEN

^$1048

American Airlines

09/10/25

3:08pm

DEN

19h 19m

CLT

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

20h 44m

MIA

DFW

09/18/25

8:13am

DEN

^$1048

American Airlines

09/10/25

1:00pm

DEN

21h 27m

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

20h 44m

MIA

DFW

09/18/25

8:13am

DEN

^$1081

American Airlines

09/10/25

7:20am

DEN

27h 7m

DFW

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

20h 44m

MIA

DFW

09/18/25

8:13am

DEN

^$1086

American Airlines

09/10/25

10:31am

DEN

23h 56m

DFW

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

20h 44m

MIA

DFW

09/18/25

8:13am

DEN

^$1086

American Airlines

09/10/25

11:57pm

DEN

10h 30m

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

21h 27m

MIA

CLT

09/18/25

8:56am

DEN

^$1114

American Airlines

09/10/25

3:08pm

DEN

19h 19m

CLT

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

21h 27m

MIA

CLT

09/18/25

8:56am

DEN

^$1114

American Airlines

09/10/25

1:00pm

DEN

21h 27m

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

21h 27m

MIA

CLT

09/18/25

8:56am

DEN

^$1147

American Airlines

09/10/25

10:31am

DEN

23h 56m

DFW

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

21h 27m

MIA

CLT

09/18/25

8:56am

DEN

^$1152

American Airlines

09/10/25

7:20am

DEN

27h 7m

DFW

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

21h 27m

MIA

CLT

09/18/25

8:56am

DEN

^$1152

American Airlines

09/10/25

11:57pm

DEN

10h 30m

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

11h 32m

MIA

09/17/25

11:01pm

DEN

^$1231

American Airlines

09/10/25

3:08pm

DEN

19h 19m

CLT

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

11h 32m

MIA

09/17/25

11:01pm

DEN

^$1235

American Airlines

09/10/25

3:08pm

DEN

19h 19m

CLT

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

22h 13m

MIA

DFW

09/18/25

9:42am

DEN

^$1235

American Airlines

09/10/25

1:00pm

DEN

21h 27m

MIA

09/11/25

12:27pm

STI

American Airlines

09/17/25

1:29pm

STI

11h 32m

MIA

09/17/25

11:01pm

DEN

^$1263

Top Deals on flights Business Class from Denver to Santiago

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

11:57pm

DEN

10h 30m

MIA

Sep 11

12:27pm

STI

as low as

^$603

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

3:08pm

DEN

19h 19m

CLT

MIA

Sep 11

12:27pm

STI

as low as

^$603

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

7:09am

DEN

27h 18m

CLT

MIA

Sep 11

12:27pm

STI

as low as

^$609

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

1:00pm

DEN

21h 27m

MIA

Sep 11

12:27pm

STI

as low as

^$641

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

10:31am

DEN

23h 56m

DFW

MIA

Sep 11

12:27pm

STI

as low as

^$646

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

7:20am

DEN

27h 7m

DFW

MIA

Sep 11

12:27pm

STI

as low as

^$652

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

11:59pm

DEN

10h 28m

CLT

MIA

Sep 11

12:27pm

STI

as low as

^$893

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

9:04am

DEN

25h 23m

DFW

MIA

Sep 11

12:27pm

STI

as low as

^$951

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

11:40am

DEN

22h 47m

LAX

MIA

Sep 11

12:27pm

STI

as low as

^$1125

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

6:00pm

DEN

16h 27m

LAX

MIA

Sep 11

12:27pm

STI

as low as

^$2978

Denver, US (DEN) - Santiago, DO (STI)

American Airlines

Sep 10

6:00am

DEN

28h 27m

LAX

MIA

Sep 11

12:27pm

STI

as low as

^$3169

Frequently Asked Questions

What are all possible destination arrival airports?

The possible destination arrival airport is Cibao International Airport, with layovers at Miami International Airport and Charlotte Douglas International Airport.

What is the time difference between destination and arrival?

The time difference between Denver and Santiago is typically 2 hours, with Santiago being ahead of Denver.

Is there a direct flight from Denver to Santiago?

There is no direct flight from Denver to Santiago. The available options include a 1 stop flight with American Airlines priced at $1048 and a 2 stops flight also with American Airlines priced at $1338.

Are there convenient layover flights from Denver to Santiago?

Yes, there are convenient layover flights from Denver to Santiago. American Airlines offers a 1 stop flight priced at $1048 with a layover in Miami and a flight time of 10 hours 30 minutes.

What are the most convenient layover airports for my flight?

The most convenient layover airports for your flight from Denver to Santiago are Miami International Airport and Charlotte Douglas International Airport.

What is the cheapest and fastest flight from Denver to Santiago?

The cheapest flight is with American Airlines for $1048, 1 stop, 10 hours 30 minutes. The fastest is also with American Airlines for $1338, 2 stops, 10 hours 28 minutes.