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Business Class Flight Deals from Chicago to Panama City from $665

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Bundle + Save

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Incredible Deals

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Nonstop
    from $1176
  • Up to 1 stop
    $1288

Airlines

  • American Airlines
    $1288
  • COPA Airlines
    $1176

Cabin Class

  • Business
    $1176

Departure Airports

  • Chicago O Hare Airport
    $1176

Arrival Airports

  • Tocumen International Airport
    $1176

Layover Airports

  • Miami International Airport
    $1288

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BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
COPA Airlines Logo
COPA Airlines

07/31/25

ORD
5h 16m
Direct

07/31/25

PTY
COPA Airlines Logo
COPA Airlines

08/07/25

PTY
5h 36m
Direct

08/08/25

ORD
$1176
COPA Airlines Logo
COPA Airlines

07/31/25

ORD
5h 16m
Direct

07/31/25

PTY
COPA Airlines Logo
COPA Airlines

08/07/25

PTY
5h 46m
Direct

08/07/25

ORD
$1176
COPA Airlines Logo
COPA Airlines

07/31/25

ORD
5h 28m
Direct

07/31/25

PTY
COPA Airlines Logo
COPA Airlines

08/07/25

PTY
5h 46m
Direct

08/07/25

ORD
$1176
COPA Airlines Logo
COPA Airlines

07/31/25

ORD
5h 28m
Direct

07/31/25

PTY
COPA Airlines Logo
COPA Airlines

08/07/25

PTY
5h 46m
Direct

08/07/25

ORD
$1176
COPA Airlines Logo
COPA Airlines

07/31/25

ORD
5h 28m
Direct

07/31/25

PTY
COPA Airlines Logo
COPA Airlines

08/07/25

PTY
5h 36m
Direct

08/08/25

ORD
$1176
COPA Airlines Logo
COPA Airlines

07/31/25

ORD
5h 28m
Direct

07/31/25

PTY
COPA Airlines Logo
COPA Airlines

08/07/25

PTY
5h 36m
Direct

08/08/25

ORD
$1176
American Airlines Logo
American Airlines

07/31/25

ORD
28h 29m
MIA

08/01/25

PTY
American Airlines Logo
American Airlines

08/07/25

PTY
8h 27m
MIA

08/07/25

ORD
$1288
American Airlines Logo
American Airlines

07/31/25

ORD
28h 29m
MIA

08/01/25

PTY
American Airlines Logo
American Airlines

08/07/25

PTY
17h 34m
MIA

08/08/25

ORD
$1503
American Airlines Logo
American Airlines

07/31/25

ORD
7h 54m
MIA

07/31/25

PTY
American Airlines Logo
American Airlines

08/07/25

PTY
8h 27m
MIA

08/07/25

ORD
$1575
American Airlines Logo
American Airlines

07/31/25

ORD
7h 54m
MIA

07/31/25

PTY
American Airlines Logo
American Airlines

08/07/25

PTY
17h 34m
MIA

08/08/25

ORD
$1790

Top Deals on flights Business Class from Chicago to Panama City

Chicago, US (CHI) - Panama City, PA (PTY)

Logo

Aug 1

ORD
25h 55m
BOG

Aug 2

PTY

as low as

$665

Chicago, US (CHI) - Panama City, PA (PTY)

Logo

Aug 1

ORD
10h 10m
BOG

Aug 2

PTY

as low as

$665

Chicago, US (CHI) - Panama City, PA (PTY)

Logo

Aug 1

ORD
18h 20m
BOG

Aug 2

PTY

as low as

$665

Chicago, US (CHI) - Panama City, PA (PTY)

Logo

Aug 1

ORD
30h 35m
BOG

Aug 2

PTY

as low as

$665

Chicago, US (CHI) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 1

ORD
7h 54m
MIA

Aug 1

PTY

as low as

$1039

Chicago, US (CHI) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 1

ORD
17h 57m
MIA

Aug 2

PTY

as low as

$1039

Chicago, US (CHI) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 1

ORD
7h 18m
MIA

Aug 1

PTY

as low as

$1039

Chicago, US (CHI) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 1

ORD
8h 15m
MIA

Aug 1

PTY

as low as

$1039

Chicago, US (CHI) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 1

ORD
9h 15m
MIA

Aug 1

PTY

as low as

$1039

Chicago, US (CHI) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 1

ORD
20h 5m
MIA

Aug 2

PTY

as low as

$1088

Chicago, US (CHI) - Panama City, PA (PTY)

American Airlines Logo
American Airlines

Aug 1

ORD
19h 18m
MIA

Aug 2

PTY

as low as

$1088

Chicago, US (CHI) - Panama City, PA (PTY)

COPA Airlines Logo
COPA Airlines

Aug 1

ORD
5h 28m
Direct

Aug 1

PTY

as low as

$1601

Flights to Panama City

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Origins
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Cabin Class
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