3 Star Hotel

Hotel S. Anna

Borgo Pio 133, Rome, Italy View Map

Hotel S. Anna1/94
Hotel S. Anna photo 2
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Hotel S. Anna

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About

Just 220 yards from St Peter’s Basilica, Sant’Anna Hotel is a 17th-century building offering elegant rooms and interiors in central Rome. Wi-Fi is free and a varied continental breakfast is available. With coffered ceilings and refined furniture, rooms have a classic-style atmosphere. They are air conditioned and feature an LCD TV and a safe. Just 435 yards from Castel Sant’Angelo, Hotel Sant’Anna is less than a 10 minute walk from Ottaviano Metro Station. The Spanish Steps are only 3 Metro stops away.

303 Reviews

9.2Exceptional
Cleanliness
9.4
Staff
9.6
Location
9.7

What Guests Say

  • “Elizabeth and Marcello were outstanding front desk staff! They were super helpful. The breakfast was delicious and the hotel and room…”
  • “Great location ! 2 minute walk to the Vatican. Hotel staff was great. Breakfast was awesome. Rooms very clean and well maintained.”
Show 50 Verified Reviews

Top Amenities

  • Restaurant
  • Free Internet Access
  • Airport Shuttle
  • Non-Smoking Rooms
Show All Amenities

Room Options

Our Best Price. GUARANTEED.

Exclusively for Priceline members Details

Economy Double Room1/4

Economy Double Room

173 sqft • 1 Queen

  • Accessible by lift
  • Air conditioning
  • Bath or Shower
  • Bidet
Twin Room1/4

Twin Room

194 sqft • 2 Single

  • Accessible by lift
  • Air conditioning
  • Bath or Shower
  • Bidet
Double Room1/4

Double Room

194 sqft • 1 Queen

  • Accessible by lift
  • Air conditioning
  • Bath or Shower
  • Bidet
Triple Room1/4

Triple Room

237 sqft • 1 Queen, 1 Single

  • Accessible by lift
  • Air conditioning
  • Bath or Shower
  • Bidet
Quadruple Room1/4

Quadruple Room

237 sqft • 1 Queen, 2 Single

  • Accessible by lift
  • Air conditioning
  • Bath or Shower
  • Bidet

Room Details and Photos

Room Amenities

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    What Guests Loved

    9.2
    Exceptional

    Based on 303 reviews

    Location

    9.7

    Cleanliness

    9.4

    Staff

    9.6

    Overall Quality

    9.2

    Pros +

    • Elizabeth and Marcello were outstanding front desk staff! They were super helpful. The breakfast was delicious and the hotel and room were kept very clean. The location was excellent and a safe area for solo travelers.
    • Great location ! 2 minute walk to the Vatican. Hotel staff was great. Breakfast was awesome. Rooms very clean and well maintained.
    • I like the neighborhood and the small, charming atmosphere. Staff is always most pleasant. I’ve stayed here many times and hope to return…

    Cons -

    • My only comment here is that the shower floor was very slippery and the provided soap made it even more difficult. Some type of non-slip mat needs to be provided to keep guests safe from falling.
    • I can’t complain. Some would consider the furnishings a bit worn, but I overlook that for the charm of the place.
    • I wish the breakfast could be complementary
    Business Traveler (54)Solo Traveler (54)Traveling as Couple (231)Family with Young Children (144)Family with Teens (1)Senior Traveler (1)Group Traveler (59)Total (800)
    10LauraPosted on: 1-19-2026

    Elizabeth and Marcello were outstanding front desk staff! They were super helpful. The breakfast was delicious and the hotel and room were kept very clean. The location was excellent and a safe area for solo travelers.

    My only comment here is that the shower floor was very slippery and the provided soap made it even more difficult. Some type of non-slip mat needs to be provided to keep guests safe from falling.

    8JessicaPosted on: 1-19-2026

    Great location ! 2 minute walk to the Vatican. Hotel staff was great. Breakfast was awesome. Rooms very clean and well maintained.

    10RichardPosted on: 1-9-2026

    I like the neighborhood and the small, charming atmosphere. Staff is always most pleasant. I’ve stayed here many times and hope to return…

    I can’t complain. Some would consider the furnishings a bit worn, but I overlook that for the charm of the place.

    10JanePosted on: 12-5-2025

    The location was wonderful! Near the Vatican which was very convenient for our earlymorning skip the line tour. The street was quiet at night which made for a lovely night’s sleep. The staff was very friendly and helpful with tips and recommendations. The rooms are a nice size for Europe and the beds and pillows were comfy. The hotel breakfast was good…wonderful coffee!

    9williamPosted on: 11-2-2025

    On the quiet side of the city near the Vatican. Once all the very busy restaurants and Vatican crowds go away in the late afternoon, very quiet area.

    I wish the breakfast could be complementary

    10MichellePosted on: 10-28-2025

    The staff was just phenomenal and went above and beyond at all times. They were so accommodating and helpful. They provided phenomenal recommendations and even helped when my father was unexpectedly inured. We loved how close everything was to the hotel and it was just a 10/10 experience.

    The only and I mean ONLY thing that would have been helpful would have been a shuttle from the airport upon our arrival. Taxis were difficult to find and outrageously expensive. Other than that, everything was fabulous.

    10JavaidPosted on: 9-29-2025

    Good location,Good atmosphere and big comfy bathtub for Wife.

    9Francisco P.Posted on: 9-24-2025

    Liked a lot the location and facilities were fine. Staff was great and helpful. Breakfast was OK. Room equipment was good.

    Elevator is a bit too small.

    8ValeriaPosted on: 9-1-2025

    Great location and pretty lobby

    The beds were too firm

    10Mary-JoePosted on: 8-30-2025

    LocationCleanliness/good breakfastWonderful and super helpful staff

    We liked everything

    10MichellePosted on: 8-27-2025

    Close to the Vatican, very friendly staff, cute room

    10MauroPosted on: 8-5-2025

    It was great value for the money. It’s a clean and well run hotel just steps from St. Peter’s on a car-free street.

    9DavidPosted on: 7-24-2025

    Location was great. Vatican City area was a great place to be! Very quaint, nice shower, AC worked very well. Walk out the front door with plenty of eating options and easy stroll to the Vatican. Front desk staff were great and booked our car to the airport. Lots of good recommendations. By far the best all around experience we had on our Italy trip.

    10AmyPosted on: 7-19-2025

    I can’t say enough about this property! It was a wonderful experience! The small hotel sits on a street that is quintessential Italy. There’s a gelato spot next-door, multiple restaurants with outdoor seating. The hotel was beautifully maintained. And our room was fabulous. It was steps from the Vatican. We have stayed at a lot of places in Italy and this is the one that I would recommend over any other.

    There was nothing that we can say we didn’t like-everything was great

    9MažulPosted on: 7-11-2025

    I was visiting Rome with my mom, and she wanted to spend more time around the Vatican. The location was perfect! The staff was extremely helpful, and the rooms were cleaned daily.

    9AryePosted on: 7-10-2025

    Clean and comfortable

    No closets and a bit small

    9EileenPosted on: 6-25-2025

    Location was fantastic! Staff were very knowledgeable and helpful.

    Breakfast was a little disappointing.

    10WilliamsonPosted on: 6-21-2025

    Great location, wonderful staff, nice hotel

    Mattress was very firm

    10DavidPosted on: 6-16-2025

    2 minute walk to the Vatican,restaurants and shopping

    9JaimePosted on: 5-30-2025

    Spacious and clean room, friendly staff, excellent location in relation to the Vatican Museum, spacious bathroom with bidet, breakfast was okay

    Tiny and slow elevator that can only hold 3 persons (with luggages only 1 person)

    Amenities & Policies

    Amenities

    Food & Drinks

    • Restaurant

    Media & Technology

    • Free Internet Access

    Transportation

    • Airport Shuttle

    Health & Safety

    • Health Services
    • Daily disinfection
    • Professional cleaning services

    Kid Friendly

    • Family Friendly

    General

    • No Smoking Rooms/Facilities

    Guest policies

    Check-inAfter 1:30 PM
    Check-outBefore 10:30 AM
    InternetFree Wi-Fi is available.
    Children & Extra BedsChildren of all ages are welcome. Children of age 0 to 2 stay free with cot.
    PetsPets are not allowed.
    Room RatesAll rates displayed are for two guests unless otherwise noted.

    Important info

    If you require an invoice when booking a prepaid rate, write this and your company details in the Special Requests box. Please inform of your expected arrival time in advance. You can use the Special Requests box when booking, or contact the property directly using the contact details in your confirmation. Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. Guests under the age of 18 can only check in with a parent or official guardian.

    Location

    Hotel S. Anna

    Borgo Pio 133, Rome

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