$149 Flight Deals from Tampa to Knoxville

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Stops

Up to 1 stop
$318

Airlines

American Airlines
$318
United Airlines
$318

Cabin Class

Economy
$318

Departure Airports

Tampa International Airport
$318

Arrival Airports

McGhee Tyson Airport
$318

Layover Airports

Charlotte Douglas International Airport
$318
Chicago O Hare Airport
$318
George Bush Intercontinental Houston Airport
$318
Washington Dulles Airport
$318

Best Price. GUARANTEED.

Exclusively for Priceline Members
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On average save $240 per traveler

American Airlines

09/09/25

1:06pm

TPA

4h 7m

CLT

09/09/25

5:13pm

TYS

American Airlines

09/16/25

7:45pm

TYS

3h 34m

CLT

09/16/25

11:19pm

TPA

^$318

American Airlines

09/09/25

7:15am

TPA

4h 35m

CLT

09/09/25

11:50am

TYS

American Airlines

09/16/25

7:45pm

TYS

3h 34m

CLT

09/16/25

11:19pm

TPA

^$318

American Airlines

09/09/25

6:47pm

TPA

4h 16m

CLT

09/09/25

11:03pm

TYS

American Airlines

09/16/25

7:45pm

TYS

3h 34m

CLT

09/16/25

11:19pm

TPA

^$318

American Airlines

09/09/25

4:49pm

TPA

4h 1m

CLT

09/09/25

8:50pm

TYS

American Airlines

09/16/25

8:23am

TYS

3h 53m

CLT

09/16/25

12:16pm

TPA

^$318

United Airlines

09/09/25

4:15pm

TPA

6h 30m

ORD

09/09/25

10:45pm

TYS

United Airlines

09/16/25

7:25pm

TYS

5h 13m

IAD

09/17/25

12:38am

TPA

^$318

United Airlines

09/09/25

5:15pm

TPA

6h 29m

IAH

09/09/25

11:44pm

TYS

United Airlines

09/16/25

7:25pm

TYS

5h 13m

IAD

09/17/25

12:38am

TPA

^$318

American Airlines

09/09/25

1:06pm

TPA

5h 44m

CLT

09/09/25

6:50pm

TYS

American Airlines

09/16/25

7:45pm

TYS

3h 34m

CLT

09/16/25

11:19pm

TPA

^$318

American Airlines

09/09/25

4:49pm

TPA

4h 1m

CLT

09/09/25

8:50pm

TYS

American Airlines

09/16/25

7:45pm

TYS

3h 34m

CLT

09/16/25

11:19pm

TPA

^$318

American Airlines

09/09/25

6:00am

TPA

3h 56m

CLT

09/09/25

9:56am

TYS

American Airlines

09/16/25

7:45pm

TYS

3h 34m

CLT

09/16/25

11:19pm

TPA

^$318

American Airlines

09/09/25

1:06pm

TPA

4h 7m

CLT

09/09/25

5:13pm

TYS

American Airlines

09/16/25

8:23am

TYS

3h 53m

CLT

09/16/25

12:16pm

TPA

^$318

American Airlines

09/09/25

6:47pm

TPA

4h 16m

CLT

09/09/25

11:03pm

TYS

American Airlines

09/16/25

8:23am

TYS

3h 53m

CLT

09/16/25

12:16pm

TPA

^$318

United Airlines

09/09/25

6:28pm

TPA

5h 29m

IAD

09/09/25

11:57pm

TYS

United Airlines

09/16/25

7:25pm

TYS

5h 13m

IAD

09/17/25

12:38am

TPA

^$318

United Airlines

09/09/25

11:46am

TPA

8h 7m

IAH

09/09/25

7:53pm

TYS

United Airlines

09/16/25

7:25pm

TYS

5h 13m

IAD

09/17/25

12:38am

TPA

^$318

American Airlines

09/09/25

6:00am

TPA

3h 56m

CLT

09/09/25

9:56am

TYS

American Airlines

09/16/25

5:05am

TYS

5h 19m

CLT

09/16/25

10:24am

TPA

^$318

American Airlines

09/09/25

7:15am

TPA

4h 35m

CLT

09/09/25

11:50am

TYS

American Airlines

09/16/25

8:23am

TYS

3h 53m

CLT

09/16/25

12:16pm

TPA

^$318

American Airlines

09/09/25

6:00am

TPA

3h 56m

CLT

09/09/25

9:56am

TYS

American Airlines

09/16/25

8:23am

TYS

3h 53m

CLT

09/16/25

12:16pm

TPA

^$318

United Airlines

09/09/25

6:28pm

TPA

5h 29m

IAD

09/09/25

11:57pm

TYS

United Airlines

09/16/25

2:00pm

TYS

5h 34m

ORD

09/16/25

7:34pm

TPA

^$348

United Airlines

09/09/25

11:46am

TPA

8h 7m

IAH

09/09/25

7:53pm

TYS

United Airlines

09/16/25

2:00pm

TYS

5h 34m

ORD

09/16/25

7:34pm

TPA

^$348

United Airlines

09/09/25

5:15pm

TPA

6h 29m

IAH

09/09/25

11:44pm

TYS

United Airlines

09/16/25

2:00pm

TYS

5h 34m

ORD

09/16/25

7:34pm

TPA

^$348

United Airlines

09/09/25

4:15pm

TPA

6h 30m

ORD

09/09/25

10:45pm

TYS

United Airlines

09/16/25

2:00pm

TYS

5h 34m

ORD

09/16/25

7:34pm

TPA

^$348

United Airlines

09/09/25

11:46am

TPA

11h 58m

IAH

09/09/25

11:44pm

TYS

United Airlines

09/16/25

7:25pm

TYS

5h 13m

IAD

09/17/25

12:38am

TPA

^$397

United Airlines

09/09/25

6:28pm

TPA

5h 29m

IAD

09/09/25

11:57pm

TYS

United Airlines

09/16/25

10:54am

TYS

8h 40m

ORD

09/16/25

7:34pm

TPA

^$397

United Airlines

09/09/25

11:46am

TPA

8h 7m

IAH

09/09/25

7:53pm

TYS

United Airlines

09/16/25

10:54am

TYS

8h 40m

ORD

09/16/25

7:34pm

TPA

^$397

United Airlines

09/09/25

4:15pm

TPA

6h 30m

ORD

09/09/25

10:45pm

TYS

United Airlines

09/16/25

10:54am

TYS

8h 40m

ORD

09/16/25

7:34pm

TPA

^$397

United Airlines

09/09/25

5:15pm

TPA

6h 29m

IAH

09/09/25

11:44pm

TYS

United Airlines

09/16/25

10:54am

TYS

8h 40m

ORD

09/16/25

7:34pm

TPA

^$397

United Airlines

09/09/25

4:15pm

TPA

6h 30m

ORD

09/09/25

10:45pm

TYS

United Airlines

09/16/25

5:45am

TYS

9h 20m

IAD

09/16/25

3:05pm

TPA

^$407

United Airlines

09/09/25

5:15pm

TPA

6h 29m

IAH

09/09/25

11:44pm

TYS

United Airlines

09/16/25

5:45am

TYS

14h 5m

IAD

09/16/25

7:50pm

TPA

^$407

United Airlines

09/09/25

5:15pm

TPA

6h 29m

IAH

09/09/25

11:44pm

TYS

United Airlines

09/16/25

5:45am

TYS

9h 20m

IAD

09/16/25

3:05pm

TPA

^$407

United Airlines

09/09/25

5:15pm

TPA

6h 29m

IAH

09/09/25

11:44pm

TYS

United Airlines

09/16/25

5:45am

TYS

18h 53m

IAD

09/17/25

12:38am

TPA

^$407

United Airlines

09/09/25

6:28pm

TPA

5h 29m

IAD

09/09/25

11:57pm

TYS

United Airlines

09/16/25

5:45am

TYS

9h 20m

IAD

09/16/25

3:05pm

TPA

^$407

Top Deals on flights from Tampa to Knoxville

Tampa, US (TPA) - Knoxville, US (TYS)

Oct 29

1:59pm

TPA

7h 14m

DTW

Oct 29

9:13pm

TYS

as low as

^$149

Tampa, US (TPA) - Knoxville, US (TYS)

Oct 27

6:37am

TPA

12h 55m

DEN

Oct 27

7:32pm

TYS

as low as

^$149

Tampa, US (TPA) - Knoxville, US (TYS)

Oct 27

3:56pm

TPA

5h 17m

DTW

Oct 27

9:13pm

TYS

as low as

^$186

Tampa, US (TPA) - Knoxville, US (TYS)

Oct 4

1:37pm

TPA

3h 26m

ATL

Oct 4

5:03pm

TYS

as low as

^$186

Tampa, US (TPA) - Knoxville, US (TYS)

American Airlines

Oct 31

11:18am

TPA

25h 44m

LGA

Nov 1

1:02pm

TYS

as low as

^$244

Tampa, US (TPA) - Knoxville, US (TYS)

United Airlines

Oct 29

9:40am

TPA

8h 24m

IAH

Oct 29

6:04pm

TYS

as low as

^$273

Tampa, US (TPA) - Knoxville, US (TYS)

United Airlines

Oct 27

6:50pm

TPA

5h 9m

IAD

Oct 27

11:59pm

TYS

as low as

^$273

Tampa, US (TPA) - Knoxville, US (TYS)

United Airlines

Sep 9

4:15pm

TPA

6h 30m

ORD

Sep 9

10:45pm

TYS

as low as

^$273

Tampa, US (TPA) - Knoxville, US (TYS)

American Airlines

Oct 27

5:11pm

TPA

4h 52m

CLT

Oct 27

10:03pm

TYS

as low as

^$273

Tampa, US (TPA) - Knoxville, US (TYS)

United Airlines

Oct 4

5:23pm

TPA

6h 20m

IAH

Oct 4

11:43pm

TYS

as low as

^$273

Tampa, US (TPA) - Knoxville, US (TYS)

American Airlines

Sep 9

1:06pm

TPA

5h 44m

CLT

Sep 9

6:50pm

TYS

as low as

^$273

Tampa, US (TPA) - Knoxville, US (TYS)

United Airlines

Oct 31

7:09pm

TPA

4h 50m

IAD

Oct 31

11:59pm

TYS

as low as

^$273

Frequently Asked Questions

What is the cheapest and fastest flight from Tampa to Knoxville?

The cheapest flight is with American Airlines at $318, taking 3 hours 56 minutes. The fastest option is the same flight, so no alternative is available.

What are all possible destination arrival airports?

The possible destination arrival airport for your flight is McGhee Tyson Airport in Knoxville, Tennessee, with layovers at Charlotte Douglas International Airport and Washington Dulles Airport.

What is the time difference between destination and arrival?

Knoxville is one hour behind Tampa, so expect a one-hour difference in local time upon arrival.

Is there a direct flight from Tampa to Knoxville?

There is no direct flight from Tampa International Airport to McGhee Tyson Airport. The available options are 1 stop flights with American Airlines and United Airlines, both priced at $318.

Are there convenient layover flights from Tampa to Knoxville?

Yes, there are convenient layover flights from Tampa to Knoxville with American Airlines for $318 (layover in Charlotte, flight time 3h 56m) and United Airlines for $318 (layover in Washington, flight time 5h 29m).

What are the most convenient layover airports for the flight?

The most convenient layover airports for your flight from Tampa to Knoxville are Charlotte Douglas International (American Airlines) and Washington Dulles Airport (United Airlines).

Flight Deals from Tampa to Knoxville from $149

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights from Tampa to Knoxville

Frequently Asked Questions

Flights to Knoxville