
Flight Deals from San Diego to Santiago from $533
Top flight deals from leading airlines:







... and +100s more
Save up to 50% on select flights with Priceline
Save an average of $240 per person when bundling your flight and hotel together with Priceline
If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference
We’re always here for you - reach us 24 hours a day, 7 days a week
Stops
- Up to 1 stop$1042
- Up to 2 stops$1040
Airlines
- American Airlines$1085
- LATAM Airlines Group$1040
Cabin Class
- Economy$1040
Departure Airports
- Mc Clellan-Palomar Airport$1130
- San Diego International Airport$1040
Arrival Airports
- Comodoro Arturo Merino Benítez International Airport$1040
Layover Airports
- Chicago O Hare Airport$1279
- Dallas Fort Worth International Airport$1085
- El Dorado International Airport$1063
- Hartsfield Jackson Atlanta International Airport$1062
- Jorge Chávez International Airport$1040
- Los Angeles International Airport$1040
- Miami International Airport$1062
- New York John F Kennedy Airport$1207
- Orlando International Airport$1063
- Phoenix Sky Harbor International Airport$1091
Best Price. GUARANTEED.
Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.
Book a flight & hotel together for extra savings.

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Top Deals on flights from San Diego to Santiago
San Diego, US (SAN) - Santiago, CL (SCL)

Dec 31
Jan 1
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Oct 7
Oct 8
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Oct 7
Oct 8
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Dec 30
Dec 31
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Dec 31
Jan 1
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Jan 1
Jan 2
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Dec 31
Jan 1
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Dec 31
Jan 1
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Oct 7
Oct 8
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Nov 19
Nov 20
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Dec 27
Dec 28
as low as
San Diego, US (SAN) - Santiago, CL (SCL)

Mar 28
Mar 30
as low as
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