$168 Flight Deals from San Diego to Panama City

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... and +100s more

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Stops

Nonstop
from $436
Up to 1 stop
$402
Up to 2 stops
$407

Airlines

American Airlines
$487
COPA Airlines
$436
United Airlines
$402

Cabin Class

Economy
$402

Departure Airports

San Diego International Airport
$402

Arrival Airports

Tocumen International Airport
$402

Layover Airports

Charlotte Douglas International Airport
$663
Dallas Fort Worth International Airport
$487
George Bush Intercontinental Houston Airport
$402
Los Angeles International Airport
$630
Miami International Airport
$487
Phoenix Sky Harbor International Airport
$487
San Francisco International Airport
$402

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
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BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

United Airlines

11/07/25

7:50pm

SAN

22h 59m

SFO

11/08/25

6:49pm

PTY

United Airlines

11/22/25

8:55am

PTY

11h 10m

IAH

11/22/25

8:05pm

SAN

^$402

United Airlines

11/22/25

7:50pm

SAN

22h 59m

SFO

11/23/25

6:49pm

PTY

United Airlines

11/27/25

8:55am

PTY

11h 10m

IAH

11/27/25

8:05pm

SAN

^$402

United Airlines

11/16/25

5:00pm

SAN

21h 45m

IAH

11/17/25

2:45pm

PTY

United Airlines

11/28/25

3:35pm

PTY

8h 38m

SFO

11/29/25

12:13am

SAN

^$402

United Airlines

10/29/25

5:00pm

SAN

20h 45m

IAH

10/30/25

1:45pm

PTY

United Airlines

11/16/25

3:35pm

PTY

8h 38m

SFO

11/17/25

12:13am

SAN

^$402

United Airlines

11/07/25

4:01pm

SAN

22h 44m

SFO

IAH

11/08/25

2:45pm

PTY

United Airlines

11/22/25

4:41pm

PTY

15h 25m

IAH

SFO

11/23/25

8:06am

SAN

^$407

United Airlines

11/07/25

7:50pm

SAN

22h 59m

SFO

11/08/25

6:49pm

PTY

United Airlines

11/22/25

4:41pm

PTY

15h 25m

IAH

SFO

11/23/25

8:06am

SAN

^$407

COPA Airlines

10/29/25

9:07pm

SAN

8h 13m

Direct

10/30/25

5:20am

PTY

COPA Airlines

11/16/25

1:15pm

PTY

3h 48m

Direct

11/16/25

5:03pm

SAN

^$436

United Airlines

11/12/25

5:00pm

SAN

21h 45m

IAH

11/13/25

2:45pm

PTY

United Airlines

12/10/25

11:35am

PTY

6h 46m

IAH

12/10/25

6:21pm

SAN

^$460

COPA Airlines

11/16/25

8:10pm

SAN

9h 10m

Direct

11/17/25

5:20am

PTY

COPA Airlines

11/28/25

1:15pm

PTY

3h 48m

Direct

11/28/25

5:03pm

SAN

^$471

United Airlines

11/23/25

7:50pm

SAN

22h 59m

SFO

11/24/25

6:49pm

PTY

United Airlines

11/30/25

4:41pm

PTY

27h 24m

IAH

12/01/25

8:05pm

SAN

^$472

American Airlines

11/07/25

2:55pm

SAN

22h 41m

DFW

MIA

11/08/25

1:36pm

PTY

American Airlines

11/22/25

2:43pm

PTY

18h 4m

MIA

PHX

11/23/25

8:47am

SAN

^$487

COPA Airlines

11/12/25

8:10pm

SAN

9h 10m

Direct

11/13/25

5:20am

PTY

COPA Airlines

12/10/25

1:15pm

PTY

3h 52m

Direct

12/10/25

5:07pm

SAN

^$494

American Airlines

11/07/25

2:55pm

SAN

22h 41m

DFW

MIA

11/08/25

1:36pm

PTY

American Airlines

11/22/25

2:43pm

PTY

20h 42m

MIA

11/23/25

11:25am

SAN

^$501

COPA Airlines

11/23/25

8:10pm

SAN

9h 10m

Direct

11/24/25

5:20am

PTY

COPA Airlines

11/30/25

1:15pm

PTY

3h 48m

Direct

11/30/25

5:03pm

SAN

^$506

United Airlines

11/21/25

5:00pm

SAN

26h 38m

IAH

11/22/25

7:38pm

PTY

United Airlines

11/27/25

8:55am

PTY

11h 10m

IAH

11/27/25

8:05pm

SAN

^$573

American Airlines

11/08/25

12:25pm

SAN

25h 11m

MIA

11/09/25

1:36pm

PTY

American Airlines

11/22/25

2:43pm

PTY

20h 42m

MIA

11/23/25

11:25am

SAN

^$574

American Airlines

11/08/25

12:25pm

SAN

25h 11m

MIA

11/09/25

1:36pm

PTY

American Airlines

11/22/25

2:43pm

PTY

18h 4m

MIA

PHX

11/23/25

8:47am

SAN

^$586

American Airlines

11/07/25

12:25pm

SAN

25h 11m

MIA

11/08/25

1:36pm

PTY

American Airlines

11/22/25

2:43pm

PTY

20h 42m

MIA

11/23/25

11:25am

SAN

^$596

American Airlines

11/08/25

2:55pm

SAN

22h 41m

DFW

MIA

11/09/25

1:36pm

PTY

American Airlines

11/22/25

2:43pm

PTY

17h 51m

MIA

DFW

11/23/25

8:34am

SAN

^$611

COPA Airlines

11/16/25

8:40pm

SAN

13h 45m

LAX

11/17/25

10:25am

PTY

COPA Airlines

11/28/25

1:15pm

PTY

3h 48m

Direct

11/28/25

5:03pm

SAN

^$630

COPA Airlines

10/29/25

5:55pm

SAN

16h 51m

SFO

10/30/25

10:46am

PTY

COPA Airlines

11/16/25

1:15pm

PTY

3h 48m

Direct

11/16/25

5:03pm

SAN

^$630

COPA Airlines

11/12/25

8:10pm

SAN

9h 10m

Direct

11/13/25

5:20am

PTY

COPA Airlines

12/10/25

6:14pm

PTY

16h 7m

LAX

12/11/25

10:21am

SAN

^$636

American Airlines

12/01/25

10:02pm

SAN

15h 34m

CLT

MIA

12/02/25

1:36pm

PTY

American Airlines

12/14/25

4:15pm

PTY

16h 16m

MIA

PHX

12/15/25

8:31am

SAN

^$663

American Airlines

12/01/25

10:02pm

SAN

15h 34m

CLT

MIA

12/02/25

1:36pm

PTY

American Airlines

12/14/25

2:45pm

PTY

9h 1m

MIA

12/14/25

11:46pm

SAN

^$663

COPA Airlines

11/23/25

8:40pm

SAN

13h 45m

LAX

11/24/25

10:25am

PTY

COPA Airlines

11/30/25

1:15pm

PTY

3h 48m

Direct

11/30/25

5:03pm

SAN

^$665

COPA Airlines

11/12/25

8:40pm

SAN

13h 45m

LAX

11/13/25

10:25am

PTY

COPA Airlines

12/10/25

6:14pm

PTY

16h 7m

LAX

12/11/25

10:21am

SAN

^$830

COPA Airlines

10/29/25

5:55pm

SAN

16h 51m

SFO

10/30/25

10:46am

PTY

COPA Airlines

11/16/25

6:24pm

PTY

15h 57m

LAX

11/17/25

10:21am

SAN

^$830

COPA Airlines

11/22/25

7:50pm

SAN

14h 56m

SFO

11/23/25

10:46am

PTY

COPA Airlines

11/27/25

6:24pm

PTY

15h 57m

LAX

11/28/25

10:21am

SAN

^$830

American Airlines

11/22/25

4:25pm

SAN

21h 11m

PHX

MIA

11/23/25

1:36pm

PTY

American Airlines

11/30/25

2:43pm

PTY

20h 42m

MIA

12/01/25

11:25am

SAN

^$1076

American Airlines

11/22/25

7:30pm

SAN

18h 6m

PHX

MIA

11/23/25

1:36pm

PTY

American Airlines

11/30/25

2:43pm

PTY

17h 51m

MIA

DFW

12/01/25

8:34am

SAN

^$1150

Top Deals on flights from San Diego to Panama City

San Diego, US (SAN) - Panama City, PA (PTY)

United Airlines

Sep 14

8:37pm

SAN

22h

LAX

IAH

Sep 15

6:37pm

PTY

as low as

^$168

San Diego, US (SAN) - Panama City, PA (PTY)

United Airlines

Sep 14

6:15am

SAN

12h 22m

IAH

Sep 14

6:37pm

PTY

as low as

^$168

San Diego, US (SAN) - Panama City, PA (PTY)

United Airlines

Sep 7

8:00am

SAN

12h 10m

SFO

Sep 7

8:10pm

PTY

as low as

^$168

San Diego, US (SAN) - Panama City, PA (PTY)

COPA Airlines

Nov 26

8:10pm

SAN

9h 10m

Direct

Nov 27

5:20am

PTY

as low as

^$188

San Diego, US (SAN) - Panama City, PA (PTY)

American Airlines

Sep 19

10:45pm

SAN

15h 46m

PHL

MIA

Sep 20

2:31pm

PTY

as low as

^$208

San Diego, US (SAN) - Panama City, PA (PTY)

American Airlines

Oct 3

3:01pm

SAN

23h 30m

DFW

MIA

Oct 4

2:31pm

PTY

as low as

^$208

San Diego, US (SAN) - Panama City, PA (PTY)

American Airlines

Sep 14

10:38pm

SAN

15h 53m

ORD

MIA

Sep 15

2:31pm

PTY

as low as

^$208

San Diego, US (SAN) - Panama City, PA (PTY)

American Airlines

Sep 18

7:32pm

SAN

18h 59m

PHX

MIA

Sep 19

2:31pm

PTY

as low as

^$269

San Diego, US (SAN) - Panama City, PA (PTY)

American Airlines

Sep 14

12:25pm

CLD

26h 6m

PHX

MIA

Sep 15

2:31pm

PTY

as low as

^$349

San Diego, US (SAN) - Panama City, PA (PTY)

American Airlines

Jan 16

2:25pm

SAN

22h 45m

CLT

MIA

Jan 17

1:10pm

PTY

as low as

^$380

San Diego, US (SAN) - Panama City, PA (PTY)

Feb 12

2:00pm

SAN

24h 2m

ATL

Feb 13

2:02pm

PTY

as low as

^$389

San Diego, US (SAN) - Panama City, PA (PTY)

Sep 19

8:37pm

SAN

18h 8m

LAX

SAL

Sep 20

2:45pm

PTY

as low as

^$518

Frequently Asked Questions

What is the time difference between destination and arrival?

The time difference between San Diego and Panama City is 2 hours; Panama City is 2 hours ahead.

Is there a direct flight from San Diego to Panama City?

Yes, there are direct flights from San Diego International Airport to Tocumen International Airport. COPA Airlines offers a non-stop flight priced at $436, with a flight time of 8 hours 13 minutes. United Airlines also has a non-stop flight at $4638 with the same flight time.

Are there convenient layover flights from San Diego to Panama City?

Yes, there are several convenient layover flights from San Diego to Panama City. United Airlines offers a 1 stop flight for $402 with a layover in Houston, and American Airlines provides a 1 stop option for $574 with a layover in Miami. Additionally, there are 2 stop flights available.

What are the most convenient layover airports for my flight to Panama City?

The most convenient layover airports for your flight from San Diego to Panama City are George Bush Intercontinental, Miami International, and San Francisco International.

What is the cheapest and fastest flight from San Diego to Panama City?

The cheapest flight is with United Airlines for $402, taking 20 hours 45 minutes. The fastest flight is with COPA Airlines for $436, taking 8 hours 13 minutes.

What are all possible destination arrival airports?

The possible destination arrival airport is Tocumen International Airport in Panama City.

Flights to Panama City

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Panama
Panama City

Top Destinations

Origins

Return flights

Cabin Class

➔ Flights From Panama City To San Diego

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Flight Deals from San Diego to Panama City from $168

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights from San Diego to Panama City

Frequently Asked Questions

Flights to Panama City