$402 Flight Deals from Panama City to Houston

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Stops

Up to 1 stop
$795
Up to 2 stops
$886

Airlines

Aeromexico
$846
American Airlines
$882
AVIANCA
$1812
Delta Air Lines
$795

Cabin Class

Economy
$795

Departure Airports

Tocumen International Airport
$795

Arrival Airports

George Bush Intercontinental Houston Airport
$795
William P Hobby Airport
$886

Layover Airports

Dallas Fort Worth International Airport
$886
El Dorado International Airport
$1812
Fort Lauderdale Hollywood International Airport
$1812
Hartsfield Jackson Atlanta International Airport
$795
Licenciado Benito Juarez International Airport
$846
Miami International Airport
$882
Monseñor Óscar Arnulfo Romero International Airport
$1812

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BUNDLE & SAVE

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On average save $240 per traveler

Delta Air Lines

11/11/25

3:17pm

PTY

17h 27m

ATL

11/12/25

8:44am

IAH

Delta Air Lines

12/09/25

6:00am

IAH

7h 52m

ATL

12/09/25

1:52pm

PTY

^$795

Aeromexico

11/11/25

3:02pm

PTY

25h 1m

MEX

11/12/25

4:03pm

IAH

Aeromexico

12/09/25

5:34pm

IAH

20h 13m

MEX

12/10/25

1:47pm

PTY

^$846

American Airlines

11/11/25

2:43pm

PTY

9h 47m

MIA

11/12/25

12:30am

IAH

American Airlines

12/09/25

5:49am

IAH

7h 36m

MIA

12/09/25

1:25pm

PTY

^$882

American Airlines

11/04/25

2:43pm

PTY

9h 47m

MIA

11/05/25

12:30am

IAH

American Airlines

11/25/25

5:46am

IAH

7h 50m

MIA

11/25/25

1:36pm

PTY

^$882

American Airlines

11/26/25

2:43pm

PTY

9h 47m

MIA

11/27/25

12:30am

IAH

American Airlines

12/10/25

5:49am

IAH

7h 36m

MIA

12/10/25

1:25pm

PTY

^$882

American Airlines

11/26/25

2:43pm

PTY

17h 59m

MIA

DFW

11/27/25

8:42am

HOU

American Airlines

12/10/25

5:49am

HOU

7h 36m

MIA

12/10/25

1:25pm

PTY

^$886

American Airlines

11/26/25

2:43pm

PTY

17h 59m

MIA

DFW

11/27/25

8:42am

HOU

American Airlines

12/10/25

5:00am

HOU

10h 25m

DFW

MIA

12/10/25

3:25pm

PTY

^$886

American Airlines

11/24/25

2:43pm

PTY

18h 57m

MIA

DFW

11/25/25

9:40am

HOU

American Airlines

11/30/25

5:46am

HOU

7h 50m

MIA

11/30/25

1:36pm

PTY

^$1082

American Airlines

11/24/25

2:43pm

PTY

18h 57m

MIA

DFW

11/25/25

9:40am

HOU

American Airlines

11/30/25

8:20pm

HOU

17h 16m

DFW

MIA

12/01/25

1:36pm

PTY

^$1154

AVIANCA

11/22/25

8:05pm

PTY

15h

SAL

11/23/25

11:05am

IAH

AVIANCA

11/29/25

7:30am

IAH

25h 20m

FLL

BOG

11/30/25

8:50am

PTY

^$1812

AVIANCA

11/22/25

5:55pm

PTY

17h 10m

BOG

SAL

11/23/25

11:05am

IAH

AVIANCA

11/29/25

7:30am

IAH

25h 20m

FLL

BOG

11/30/25

8:50am

PTY

^$1813

Top Deals on flights from Panama City to Houston

Panama City, PA (PTY) - Houston, US (HOU)

Aeromexico

Feb 2

3:02pm

PTY

24h 39m

MEX

Feb 3

3:41pm

IAH

as low as

^$402

Panama City, PA (PTY) - Houston, US (HOU)

Sep 1

8:10pm

PTY

13h 58m

SAL

Sep 2

10:08am

IAH

as low as

^$519

Panama City, PA (PTY) - Houston, US (HOU)

AVIANCA

Sep 22

8:10pm

PTY

16h

SAL

Sep 23

12:10pm

IAH

as low as

^$526

Panama City, PA (PTY) - Houston, US (HOU)

AVIANCA

Sep 22

3:20am

PTY

12h 50m

BOG

SAL

Sep 22

4:10pm

IAH

as low as

^$526

Panama City, PA (PTY) - Houston, US (HOU)

AVIANCA

Aug 8

5:25pm

PTY

15h 25m

BOG

MIA

Aug 9

8:50am

IAH

as low as

^$678

Panama City, PA (PTY) - Houston, US (HOU)

American Airlines

Jan 20

4:40pm

PTY

6h 54m

MIA

Jan 20

11:34pm

IAH

as low as

^$802

Panama City, PA (PTY) - Houston, US (HOU)

Aug 12

10:00am

PTY

4h 26m

Direct

Aug 12

2:26pm

IAH

as low as

^$821

Panama City, PA (PTY) - Houston, US (HOU)

Feb 2

8:55am

PTY

3h 24m

Direct

Feb 2

12:19pm

IAH

as low as

^$872

Panama City, PA (PTY) - Houston, US (HOU)

American Airlines

Jan 5

4:45pm

PTY

15h 53m

MIA

DFW

Jan 6

8:38am

HOU

as low as

^$940

Panama City, PA (PTY) - Houston, US (HOU)

Aug 12

9:04am

PTY

9h 44m

TPA

Aug 12

6:48pm

IAH

as low as

^$2570

Panama City, PA (PTY) - Houston, US (HOU)

Sep 26

6:11pm

PTY

14h 26m

MCO

Sep 27

8:37am

IAH

as low as

^$2693

Panama City, PA (PTY) - Houston, US (HOU)

Nov 6

12:03pm

PTY

8h 10m

FLL

Nov 6

8:13pm

IAH

as low as

^$2693

Frequently Asked Questions

Are there convenient layover flights from Panama City to Houston?

Yes, there are convenient layover flights from Panama City to Houston. Options include Delta at $795, Aeromexico at $846, American Airlines at $882, and AVIANCA at $1812, all with one stop.

What are the most convenient layover airports for my flight from Panama City to Houston?

Consider layovers at Hartsfield Jackson Atlanta International, Miami International, Licenciado Benito Juarez International, Dallas Fort Worth International, and Monseñor Óscar Arnulfo Romero International airports for convenient options.

What are the cheapest and fastest flights from Panama City to Houston?

The cheapest flight is with Delta Air Lines for $795 with a 17h 27m travel time. The fastest flight is with American Airlines for $959 with a travel time of 8h 53m.

What are all possible destination arrival airports?

Possible destination arrival airports include George Bush Intercontinental Airport and William P. Hobby Airport in Houston.

What is the time difference between destination and arrival?

The time difference between Panama City and Houston is typically one hour, with Houston being one hour ahead of Panama City.

Is there a direct flight from origin to destination?

There is no direct flight from Panama City to Houston.

Flights to Houston

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Origins

Return flights

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Flight Deals from Panama City to Houston from $402

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights from Panama City to Houston

Frequently Asked Questions

Flights to Houston