$288 Flight Deals from Mayagueez to Buffalo

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Stops

Up to 2 stops
$601

Airlines

JetBlue
$601

Cabin Class

Economy
$601

Departure Airports

Eugenio Maria De Hostos Airport
$601

Arrival Airports

Buffalo Niagara International Airport
$601

Layover Airports

Fort Lauderdale Hollywood International Airport
$717
General Edward Lawrence Logan International Airport
$682
Luis Munoz Marin International Airport
$601
New York John F Kennedy Airport
$601
Orlando International Airport
$601

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BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

JetBlue

07/31/25

5:00pm

MAZ

16h

SJU

JFK

08/01/25

9:00am

BUF

JetBlue

08/07/25

8:30am

BUF

24h 44m

MCO

SJU

08/08/25

9:14am

MAZ

^$601

JetBlue

07/31/25

7:35am

MAZ

11h 25m

SJU

JFK

07/31/25

7:00pm

BUF

JetBlue

08/07/25

8:30am

BUF

24h 44m

MCO

SJU

08/08/25

9:14am

MAZ

^$611

JetBlue

07/31/25

5:00pm

MAZ

16h

SJU

JFK

08/01/25

9:00am

BUF

JetBlue

08/07/25

9:49am

BUF

8h 53m

BOS

SJU

08/07/25

6:42pm

MAZ

^$682

JetBlue

07/31/25

5:00pm

MAZ

16h

SJU

JFK

08/01/25

9:00am

BUF

JetBlue

08/07/25

7:22am

BUF

11h 20m

BOS

SJU

08/07/25

6:42pm

MAZ

^$683

JetBlue

07/31/25

9:36am

MAZ

12h 54m

SJU

FLL

07/31/25

10:30pm

BUF

JetBlue

08/07/25

9:49am

BUF

8h 53m

BOS

SJU

08/07/25

6:42pm

MAZ

^$717

JetBlue

07/31/25

9:36am

MAZ

12h 54m

SJU

FLL

07/31/25

10:30pm

BUF

JetBlue

08/07/25

7:22am

BUF

11h 20m

BOS

SJU

08/07/25

6:42pm

MAZ

^$719

Top Deals on flights from Mayagueez to Buffalo

Mayagueez, PR (MAZ) - Buffalo, US (BUF)

JetBlue

Aug 1

5:00pm

MAZ

19h 48m

SJU

MCO

Aug 2

12:48pm

BUF

as low as

^$288

Mayagueez, PR (MAZ) - Buffalo, US (BUF)

JetBlue

Aug 1

2:00pm

MAZ

22h 48m

SJU

MCO

Aug 2

12:48pm

BUF

as low as

^$288

Mayagueez, PR (MAZ) - Buffalo, US (BUF)

JetBlue

Aug 1

9:36am

MAZ

12h 56m

SJU

FLL

Aug 1

10:32pm

BUF

as low as

^$310

Mayagueez, PR (MAZ) - Buffalo, US (BUF)

JetBlue

Aug 1

2:00pm

MAZ

21h 42m

SJU

JFK

Aug 2

11:42am

BUF

as low as

^$324

Mayagueez, PR (MAZ) - Buffalo, US (BUF)

JetBlue

Aug 1

5:00pm

MAZ

17h 9m

SJU

BOS

Aug 2

10:09am

BUF

as low as

^$385

Mayagueez, PR (MAZ) - Buffalo, US (BUF)

JetBlue

Aug 1

2:00pm

MAZ

20h 9m

SJU

BOS

Aug 2

10:09am

BUF

as low as

^$385

Mayagueez, PR (MAZ) - Buffalo, US (BUF)

JetBlue

Aug 1

9:36am

MAZ

24h 33m

SJU

BOS

Aug 2

10:09am

BUF

as low as

^$395

Frequently Asked Questions

Cheapest and fastest flight from Mayagueez to Buffalo

The cheapest flight is with JetBlue at $601, taking 16 hours. The fastest flight is also with JetBlue at $611, taking 11 hours 25 minutes.

What are all possible destination arrival airports?

The possible destination arrival airport is Buffalo Niagara International Airport.

What is the time difference between destination and arrival?

The time difference between Mayaguez and Buffalo is approximately 1 hour, with Buffalo being ahead. Consider this when planning your travel schedule.

Is there a direct flight from Mayagueez to Buffalo?

There is no direct flight from Mayagueez to Buffalo. The cheapest option is a 2 stops flight with JetBlue at $601, and the fastest is also a 2 stops flight at $611.

Are there convenient layover flights from Mayagueez to Buffalo?

Yes, there are convenient layover flights from Mayagueez to Buffalo. JetBlue offers a 2 stops flight at $601 with layovers at Luis Munoz Marin International Airport and New York John F Kennedy Airport, taking 16 hours.

What are the most convenient layover airports for my flight?

For your flight from Mayagueez to Buffalo, convenient layover airports are Luis Munoz Marin International Airport and New York John F Kennedy Airport, both utilized by JetBlue.

Flights to Buffalo

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Flight Deals from Mayagueez to Buffalo from $288

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights from Mayagueez to Buffalo

Frequently Asked Questions

Flights to Buffalo