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Flight Deals from Buffalo to Mayagueez from $298

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Stops

  • Up to 2 stops
    $634

Airlines

  • JetBlue
    $634
  • United Airlines
    $1290

Cabin Class

  • Economy
    $634

Departure Airports

  • Buffalo Niagara International Airport
    $634

Arrival Airports

  • Eugenio Maria De Hostos Airport
    $634

Layover Airports

  • Chicago O Hare Airport
    $1318
  • General Edward Lawrence Logan International Airport
    $634
  • Luis Munoz Marin International Airport
    $634
  • New York John F Kennedy Airport
    $634
  • Newark Liberty Airport
    $1290
  • Orlando International Airport
    $640
  • Washington Dulles Airport
    $1290

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On average save $240 per traveler
JetBlue Logo
JetBlue

08/04/25

BUF
23h 29m
JFK
SJU

08/05/25

MAZ
JetBlue Logo
JetBlue

08/11/25

MAZ
25h 10m
SJU
BOS

08/12/25

BUF
$634
JetBlue Logo
JetBlue

08/04/25

BUF
20h 31m
JFK
SJU

08/05/25

MAZ
JetBlue Logo
JetBlue

08/11/25

MAZ
25h 10m
SJU
BOS

08/12/25

BUF
$634
JetBlue Logo
JetBlue

08/04/25

BUF
20h 31m
JFK
SJU

08/05/25

MAZ
JetBlue Logo
JetBlue

08/11/25

MAZ
28h 10m
SJU
BOS

08/12/25

BUF
$634
JetBlue Logo
JetBlue

08/04/25

BUF
20h 31m
JFK
SJU

08/05/25

MAZ
JetBlue Logo
JetBlue

08/11/25

MAZ
19h 48m
SJU
MCO

08/12/25

BUF
$640
JetBlue Logo
JetBlue

08/04/25

BUF
23h 29m
JFK
SJU

08/05/25

MAZ
JetBlue Logo
JetBlue

08/11/25

MAZ
19h 48m
SJU
MCO

08/12/25

BUF
$640
JetBlue Logo
JetBlue

08/04/25

BUF
20h 31m
JFK
SJU

08/05/25

MAZ
JetBlue Logo
JetBlue

08/11/25

MAZ
22h 48m
SJU
MCO

08/12/25

BUF
$640
United Airlines Logo
United Airlines

08/04/25

BUF
21h 12m
EWR
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
9h 44m
SJU
IAD

08/11/25

BUF
$1290
United Airlines Logo
United Airlines

08/04/25

BUF
20h 42m
IAD
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
9h 44m
SJU
IAD

08/11/25

BUF
$1290
United Airlines Logo
United Airlines

08/04/25

BUF
29h 57m
IAD
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
9h 44m
SJU
IAD

08/11/25

BUF
$1301
United Airlines Logo
United Airlines

08/04/25

BUF
26h 30m
ORD
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
9h 44m
SJU
IAD

08/11/25

BUF
$1318
United Airlines Logo
United Airlines

08/04/25

BUF
22h 33m
ORD
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
9h 44m
SJU
IAD

08/11/25

BUF
$1318
United Airlines Logo
United Airlines

08/04/25

BUF
29h 37m
ORD
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
9h 44m
SJU
IAD

08/11/25

BUF
$1365
United Airlines Logo
United Airlines

08/04/25

BUF
20h 42m
IAD
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
19h 54m
SJU
ORD

08/12/25

BUF
$1367
United Airlines Logo
United Airlines

08/04/25

BUF
21h 12m
EWR
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
19h 45m
SJU
IAD

08/12/25

BUF
$1367
United Airlines Logo
United Airlines

08/04/25

BUF
21h 12m
EWR
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
19h 54m
SJU
ORD

08/12/25

BUF
$1367
United Airlines Logo
United Airlines

08/04/25

BUF
29h 17m
EWR
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
9h 44m
SJU
IAD

08/11/25

BUF
$1368
United Airlines Logo
United Airlines

08/04/25

BUF
21h 12m
EWR
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
31h 1m
SJU
ORD

08/12/25

BUF
$1372
United Airlines Logo
United Airlines

08/04/25

BUF
20h 42m
IAD
SJU

08/05/25

MAZ
United Airlines Logo
United Airlines

08/11/25

MAZ
31h 1m
SJU
ORD

08/12/25

BUF
$1372

Top Deals on flights from Buffalo to Mayagueez

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
14h 59m
BOS
SJU

Aug 3

MAZ

as low as

$298

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
19h 12m
BOS
SJU

Aug 3

MAZ

as low as

$304

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
24h 27m
BOS
SJU

Aug 3

MAZ

as low as

$324

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
22h 12m
BOS
SJU

Aug 3

MAZ

as low as

$334

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
24h 58m
JFK
SJU

Aug 3

MAZ

as low as

$341

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
20h 45m
JFK
SJU

Aug 3

MAZ

as low as

$341

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
27h 39m
JFK
SJU

Aug 3

MAZ

as low as

$359

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
19h 40m
BOS
SJU

Aug 3

MAZ

as low as

$376

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
27h 58m
JFK
SJU

Aug 3

MAZ

as low as

$377

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 2

BUF
23h 53m
BOS
SJU

Aug 3

MAZ

as low as

$381

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 2

BUF
10h 27m
EWR
SJU

Aug 2

MAZ

as low as

$562

Buffalo, US (BUF) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 2

BUF
9h 42m
ORD
SJU

Aug 2

MAZ

as low as

$778

Frequently Asked Questions

What are all possible destination arrival airports?
The possible destination arrival airport is Eugenio Maria De Hostos Airport. Layover airports include New York John F Kennedy Airport, Luis Munoz Marin International Airport, and Chicago O Hare Airport.
What is the time difference between destination and arrival?
The time difference between Buffalo and Mayagueez is typically one hour, with Mayagueez being one hour ahead of Buffalo.
Is there a direct flight from Buffalo to Mayagueez?
There is no direct flight from Buffalo to Mayagueez. The available options are 2 stops flights with JetBlue priced at $634 and United Airlines priced at $1421.
Are there convenient layover flights from Buffalo to Mayagueez?
Yes, there are convenient 2 stop flights from Buffalo to Mayagueez. JetBlue offers a flight for $634 with a total travel time of 20 hours 31 minutes. United Airlines has a similar option for $1290, taking 21 hours 12 minutes.
What are the most convenient layover airports for the flight?
For your flight from Buffalo to Mayagueez, consider layovers at New York John F Kennedy Airport, Luis Munoz Marin International Airport, Chicago O Hare Airport, or Newark Liberty Airport for convenient connections.
What is the cheapest and fastest flight from Buffalo to Mayagueez?
The cheapest flight is with JetBlue for $634, taking 20 hours 31 minutes. The fastest is with United Airlines for $1421, taking 9 hours 27 minutes.
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