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Flight Deals from Detroit to South Carolina from $109

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Top Deals on flights from Detroit to Charleston

Detroit, US (DTT) - Charleston, US (CHS)

Spirit Airlines Logo
Spirit Airlines

Jul 25

DTW
2h
Direct

Jul 25

CHS
Spirit Airlines Logo
Spirit Airlines

Jul 27

CHS
2h 2m
Direct

Jul 27

DTW

as low as

$137

Detroit, US (DTT) - Charleston, US (CHS)

Spirit Airlines Logo
Spirit Airlines

Jul 10

DTW
2h
Direct

Jul 10

CHS
Spirit Airlines Logo
Spirit Airlines

Jul 17

CHS
2h 2m
Direct

Jul 17

DTW

as low as

$163

Detroit, US (DTT) - Charleston, US (CHS)

American Airlines Logo
American Airlines

Jul 31

DTW
4h 28m
CLT

Jul 31

CHS
American Airlines Logo
American Airlines

Aug 3

CHS
4h 6m
CLT

Aug 4

DTW

as low as

$288

Detroit, US (DTT) - Charleston, US (CHS)

United Airlines Logo
United Airlines

Jul 28

DTW
5h 13m
ORD

Jul 28

CHS
United Airlines Logo
United Airlines

Aug 4

CHS
8h 6m
ORD

Aug 4

DTW

as low as

$388

Detroit, US (DTT) - Charleston, US (CHS)

American Airlines Logo
American Airlines

Jul 12

DTW
5h
DCA

Jul 12

CHS
American Airlines Logo
American Airlines

Jul 19

CHS
4h 7m
CLT

Jul 19

DTW

as low as

$388

Detroit, US (DTT) - Charleston, US (CHS)

United Airlines Logo
United Airlines

Jul 31

DTW
4h 14m
IAD

Jul 31

CHS
United Airlines Logo
United Airlines

Aug 4

CHS
6h 14m
ORD

Aug 4

DTW

as low as

$388

Detroit, US (DTT) - Charleston, US (CHS)

United Airlines Logo
United Airlines

Aug 1

DTW
4h 14m
IAD

Aug 1

CHS
United Airlines Logo
United Airlines

Aug 4

CHS
6h 14m
ORD

Aug 4

DTW

as low as

$408

Detroit, US (DTT) - Charleston, US (CHS)

United Airlines Logo
United Airlines

Jul 24

DTW
4h 14m
IAD

Jul 24

CHS
United Airlines Logo
United Airlines

Jul 27

CHS
7h 12m
ORD

Jul 27

DTW

as low as

$408

Detroit, US (DTT) - Charleston, US (CHS)

American Airlines Logo
American Airlines

Jul 9

DTW
6h 39m
ORD

Jul 9

CHS
American Airlines Logo
American Airlines

Jul 13

CHS
5h 16m
CLT

Jul 13

DTW

as low as

$448

Detroit, US (DTT) - Charleston, US (CHS)

United Airlines Logo
United Airlines

Jul 12

DTW
9h 19m
EWR

Jul 12

CHS
United Airlines Logo
United Airlines

Jul 19

CHS
4h 21m
IAD

Jul 19

DTW

as low as

$515

Detroit, US (DTT) - Charleston, US (CHS)

United Airlines Logo
United Airlines

Jul 9

DTW
8h 9m
EWR

Jul 9

CHS
United Airlines Logo
United Airlines

Jul 13

CHS
7h 12m
ORD

Jul 13

DTW

as low as

$576

Detroit, US (DTT) - Charleston, US (CHS)

Alaska Airlines Logo
Alaska Airlines

Jul 12

DTW
15h 20m
SEA
DFW

Jul 12

CHS
Alaska Airlines Logo
Alaska Airlines

Jul 19

CHS
15h 28m
SEA
ORD

Jul 20

DTW

as low as

$1564

Top Deals on flights from Detroit to Myrtle Beach

Detroit, US (DTT) - Myrtle Beach, US (MYR)

Spirit Airlines Logo
Spirit Airlines

Jul 13

DTW
1h 34m
Direct

Jul 13

MYR
Spirit Airlines Logo
Spirit Airlines

Jul 17

MYR
2h 5m
Direct

Jul 17

DTW

as low as

$109

Detroit, US (DTT) - Myrtle Beach, US (MYR)

Spirit Airlines Logo
Spirit Airlines

Aug 7

DTW
1h 34m
Direct

Aug 7

MYR
Spirit Airlines Logo
Spirit Airlines

Aug 11

MYR
2h 4m
Direct

Aug 11

DTW

as low as

$109

Detroit, US (DTT) - Myrtle Beach, US (MYR)

Spirit Airlines Logo
Spirit Airlines

Jul 18

DTW
1h 42m
Direct

Jul 18

MYR
Spirit Airlines Logo
Spirit Airlines

Jul 31

MYR
2h 5m
Direct

Jul 31

DTW

as low as

$109

Detroit, US (DTT) - Myrtle Beach, US (MYR)

American Airlines Logo
American Airlines

Jul 21

DTW
4h 8m
DCA

Jul 21

MYR
American Airlines Logo
American Airlines

Jul 31

MYR
4h 54m
CLT

Aug 1

DTW

as low as

$272

Detroit, US (DTT) - Myrtle Beach, US (MYR)

American Airlines Logo
American Airlines

Aug 1

DTW
4h 31m
CLT

Aug 2

MYR
American Airlines Logo
American Airlines

Aug 4

MYR
4h 27m
CLT

Aug 4

DTW

as low as

$288

Detroit, US (DTT) - Myrtle Beach, US (MYR)

American Airlines Logo
American Airlines

Jul 18

DTW
5h 50m
CLT

Jul 18

MYR
American Airlines Logo
American Airlines

Jul 31

MYR
4h 20m
CLT

Jul 31

DTW

as low as

$312

Detroit, US (DTT) - Myrtle Beach, US (MYR)

United Airlines Logo
United Airlines

Jul 21

DTW
7h 21m
ORD

Jul 21

MYR
United Airlines Logo
United Airlines

Jul 31

MYR
5h 20m
ORD

Jul 31

DTW

as low as

$438

Detroit, US (DTT) - Myrtle Beach, US (MYR)

United Airlines Logo
United Airlines

Jul 18

DTW
7h 21m
ORD

Jul 18

MYR
United Airlines Logo
United Airlines

Jul 31

MYR
5h 20m
ORD

Jul 31

DTW

as low as

$438

Detroit, US (DTT) - Myrtle Beach, US (MYR)

United Airlines Logo
United Airlines

Jul 13

DTW
5h 45m
ORD

Jul 13

MYR
United Airlines Logo
United Airlines

Jul 17

MYR
7h 7m
ORD

Jul 17

DTW

as low as

$458

Detroit, US (DTT) - Myrtle Beach, US (MYR)

United Airlines Logo
United Airlines

Jul 24

DTW
7h 21m
ORD

Jul 24

MYR
United Airlines Logo
United Airlines

Jul 27

MYR
15h 12m
EWR

Jul 28

DTW

as low as

$471

Detroit, US (DTT) - Myrtle Beach, US (MYR)

Delta Air Lines Logo
Delta Air Lines

Jul 13

DTW
1h 54m
Direct

Jul 13

MYR
Delta Air Lines Logo
Delta Air Lines

Jul 17

MYR
5h 8m
ATL

Jul 18

DTW

as low as

$486

Detroit, US (DTT) - Myrtle Beach, US (MYR)

Delta Air Lines Logo
Delta Air Lines

Jul 13

DTW
5h 12m
ATL

Jul 13

MYR
Delta Air Lines Logo
Delta Air Lines

Jul 17

MYR
5h 8m
ATL

Jul 18

DTW

as low as

$731

Top Deals on flights from Detroit to Holly Springs

Detroit, US (DTT) - Holly Springs, US (GSP)

American Airlines Logo
American Airlines

Jul 18

DTW
4h 24m
PHL

Jul 18

GSP
American Airlines Logo
American Airlines

Jul 20

GSP
5h 46m
CLT

Jul 20

DTW

as low as

$548

Detroit, US (DTT) - Holly Springs, US (GSP)

United Airlines Logo
United Airlines

Jul 18

DTW
3h 56m
IAD

Jul 18

GSP
United Airlines Logo
United Airlines

Jul 20

GSP
4h 13m
IAD

Jul 20

DTW

as low as

$573

Detroit, US (DTT) - Holly Springs, US (GSP)

United Airlines Logo
United Airlines

Jul 21

DTW
6h 4m
ORD

Jul 21

GSP
United Airlines Logo
United Airlines

Jul 22

GSP
15h 3m
EWR

Jul 23

DTW

as low as

$595

Detroit, US (DTT) - Holly Springs, US (GSP)

Delta Air Lines Logo
Delta Air Lines

Jul 21

DTW
1h 47m
Direct

Jul 21

GSP
Delta Air Lines Logo
Delta Air Lines

Jul 25

GSP
1h 46m
Direct

Jul 25

DTW

as low as

$596

Detroit, US (DTT) - Holly Springs, US (GSP)

American Airlines Logo
American Airlines

Jul 21

DTW
13h 50m
ORD
CLT

Jul 22

GSP
American Airlines Logo
American Airlines

Jul 25

GSP
7h 18m
PHL

Jul 25

DTW

as low as

$599

Detroit, US (DTT) - Holly Springs, US (GSP)

Delta Air Lines Logo
Delta Air Lines

Jul 21

DTW
1h 47m
Direct

Jul 21

GSP
Delta Air Lines Logo
Delta Air Lines

Jul 25

GSP
6h 5m
ATL

Jul 25

DTW

as low as

$606

Detroit, US (DTT) - Holly Springs, US (GSP)

Delta Air Lines Logo
Delta Air Lines

Jul 21

DTW
3h 36m
ATL

Jul 21

GSP
Delta Air Lines Logo
Delta Air Lines

Jul 25

GSP
6h 5m
ATL

Jul 25

DTW

as low as

$616

Detroit, US (DTT) - Holly Springs, US (GSP)

American Airlines Logo
American Airlines

Jul 21

DTW
4h 24m
PHL

Jul 21

GSP
American Airlines Logo
American Airlines

Jul 25

GSP
6h 52m
CLT

Jul 26

DTW

as low as

$616

Detroit, US (DTT) - Holly Springs, US (GSP)

United Airlines Logo
United Airlines

Jul 21

DTW
6h 4m
ORD

Jul 21

GSP
United Airlines Logo
United Airlines

Jul 22

GSP
8h 18m
IAD
EWR

Jul 22

DTW

as low as

$641

Detroit, US (DTT) - Holly Springs, US (GSP)

United Airlines Logo
United Airlines

Jul 21

DTW
6h 4m
ORD

Jul 21

GSP
United Airlines Logo
United Airlines

Jul 25

GSP
1h 46m
Direct

Jul 25

DTW

as low as

$716

Detroit, US (DTT) - Holly Springs, US (GSP)

American Airlines Logo
American Airlines

Jul 21

DTW
13h 50m
ORD
CLT

Jul 22

GSP
American Airlines Logo
American Airlines

Jul 25

GSP
13h 33m
CLT
DCA

Jul 26

DTW

as low as

$774

Detroit, US (DTT) - Holly Springs, US (GSP)

United Airlines Logo
United Airlines

Jul 21

DTW
9h 12m
EWR
IAD

Jul 21

GSP
United Airlines Logo
United Airlines

Jul 22

GSP
8h 18m
IAD
EWR

Jul 22

DTW

as low as

$787

Top Deals on flights from Detroit to Columbia

Detroit, US (DTT) - Columbia, US (CAE)

Delta Air Lines Logo
Delta Air Lines

Jul 17

DTW
4h 50m
ATL

Jul 17

CAE
Delta Air Lines Logo
Delta Air Lines

Jul 22

CAE
5h 22m
ATL

Jul 22

DTW

as low as

$248

Detroit, US (DTT) - Columbia, US (CAE)

American Airlines Logo
American Airlines

Jul 17

DTW
6h 24m
CLT

Jul 17

CAE
American Airlines Logo
American Airlines

Jul 22

CAE
4h 31m
CLT

Jul 22

DTW

as low as

$318

Detroit, US (DTT) - Columbia, US (CAE)

American Airlines Logo
American Airlines

Jun 27

DTW
4h 36m
DCA

Jun 27

CAE
American Airlines Logo
American Airlines

Jun 29

CAE
5h 54m
CLT

Jun 29

DTW

as low as

$408

Detroit, US (DTT) - Columbia, US (CAE)

Delta Air Lines Logo
Delta Air Lines

Jul 31

DTW
3h 46m
ATL

Jul 31

CAE
Delta Air Lines Logo
Delta Air Lines

Aug 4

CAE
5h 47m
ATL

Aug 5

DTW

as low as

$468

Detroit, US (DTT) - Columbia, US (CAE)

United Airlines Logo
United Airlines

Aug 7

DTW
7h 35m
ORD

Aug 7

CAE
United Airlines Logo
United Airlines

Aug 14

CAE
4h 14m
IAD

Aug 14

DTW

as low as

$477

Detroit, US (DTT) - Columbia, US (CAE)

United Airlines Logo
United Airlines

Jul 3

DTW
7h 35m
ORD

Jul 3

CAE
United Airlines Logo
United Airlines

Jul 6

CAE
4h 30m
ORD

Jul 6

DTW

as low as

$511

Detroit, US (DTT) - Columbia, US (CAE)

United Airlines Logo
United Airlines

Jul 17

DTW
6h 28m
ORD

Jul 17

CAE
United Airlines Logo
United Airlines

Jul 22

CAE
4h 7m
IAD

Jul 22

DTW

as low as

$516

Detroit, US (DTT) - Columbia, US (CAE)

Delta Air Lines Logo
Delta Air Lines

Jul 1

DTW
6h 13m
ATL

Jul 1

CAE
Delta Air Lines Logo
Delta Air Lines

Jul 3

CAE
6h 40m
LGA

Jul 3

DTW

as low as

$538

Detroit, US (DTT) - Columbia, US (CAE)

American Airlines Logo
American Airlines

Jun 29

DTW
6h 39m
CLT

Jun 29

CAE
American Airlines Logo
American Airlines

Jun 30

CAE
4h 13m
DCA

Jun 30

DTW

as low as

$574

Detroit, US (DTT) - Columbia, US (CAE)

United Airlines Logo
United Airlines

Jul 1

DTW
3h 54m
IAD

Jul 1

CAE
United Airlines Logo
United Airlines

Jul 3

CAE
6h 22m
ORD

Jul 3

DTW

as low as

$574

Detroit, US (DTT) - Columbia, US (CAE)

United Airlines Logo
United Airlines

Jun 29

DTW
3h 54m
IAD

Jun 29

CAE
United Airlines Logo
United Airlines

Jun 30

CAE
4h 14m
IAD

Jun 30

DTW

as low as

$574

Detroit, US (DTT) - Columbia, US (CAE)

Delta Air Lines Logo
Delta Air Lines

Jun 29

DTW
4h 53m
ATL

Jun 29

CAE
Delta Air Lines Logo
Delta Air Lines

Jun 30

CAE
6h 20m
ATL

Jun 30

DTW

as low as

$595

Top Deals on flights from Detroit to Florence

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
6h 54m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
6h 9m
CLT

Aug 1

DTW

as low as

$544

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
3h 59m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
4h 8m
CLT

Aug 1

DTW

as low as

$544

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
3h 59m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
4h 6m
CLT

Aug 1

DTW

as low as

$544

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
4h 28m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
4h 6m
CLT

Aug 1

DTW

as low as

$544

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
4h 47m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
7h 11m
CLT
ORD

Aug 1

DTW

as low as

$549

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
8h 9m
PHL
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
4h 8m
CLT

Aug 1

DTW

as low as

$549

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
3h 59m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
7h 11m
CLT
ORD

Aug 1

DTW

as low as

$549

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
6h 54m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
7h 11m
CLT
ORD

Aug 1

DTW

as low as

$549

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
8h 9m
PHL
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
4h 6m
CLT

Aug 1

DTW

as low as

$549

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
4h 47m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
8h 14m
CLT
LGA

Aug 1

DTW

as low as

$549

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
3h 59m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
7h 22m
CLT
PHL

Aug 1

DTW

as low as

$549

Detroit, US (DTT) - Florence, US (FLO)

American Airlines Logo
American Airlines

Jul 25

DTW
4h 28m
CLT

Jul 25

FLO
American Airlines Logo
American Airlines

Aug 1

FLO
7h 11m
CLT
ORD

Aug 1

DTW

as low as

$549