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Business Class Flight Deals to Syracuse from $475

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Bundle + Save

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Incredible Deals

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Up to 1 stop
    $525

Airlines

  • American Airlines
    $525

Cabin Class

  • First
    $525

Departure Airports

  • Detroit Metropolitan Airport
    $525

Arrival Airports

  • Syracuse Hancock International Airport
    $525

Layover Airports

  • Charlotte Douglas International Airport
    $551
  • Chicago O Hare Airport
    $525
  • Philadelphia International Airport
    $552
  • Reagan Washington National Airport
    $525

Best Price. GUARANTEED.

Exclusively for Priceline Members
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On average save $240 per traveler
American Airlines Logo
American Airlines

07/23/25

DTW
4h 37m
ORD

07/23/25

SYR
American Airlines Logo
American Airlines

07/30/25

SYR
3h 38m
DCA

07/30/25

DTW
$525
American Airlines Logo
American Airlines

07/23/25

DTW
7h 31m
CLT

07/23/25

SYR
American Airlines Logo
American Airlines

07/30/25

SYR
3h 38m
DCA

07/30/25

DTW
$551
American Airlines Logo
American Airlines

07/23/25

DTW
4h 34m
PHL

07/23/25

SYR
American Airlines Logo
American Airlines

07/30/25

SYR
3h 38m
DCA

07/30/25

DTW
$552

Top Deals on flights Business Class to Syracuse

, () - Syracuse, US (SYR)

American Airlines Logo
American Airlines

Jul 25

DEN
15h 33m
ORD

Jul 26

SYR

as low as

$475

, () - Syracuse, US (SYR)

American Airlines Logo
American Airlines

Jul 25

DEN
28h 21m
ORD

Jul 26

SYR

as low as

$475

, () - Syracuse, US (SYR)

American Airlines Logo
American Airlines

Jul 25

DEN
6h 45m
CLT

Jul 25

SYR

as low as

$553

, () - Syracuse, US (SYR)

American Airlines Logo
American Airlines

Jul 25

DEN
8h 15m
DFW

Jul 25

SYR

as low as

$553

, () - Syracuse, US (SYR)

American Airlines Logo
American Airlines

Jul 25

DEN
9h 25m
CLT

Jul 26

SYR

as low as

$553

, () - Syracuse, US (SYR)

American Airlines Logo
American Airlines

Jul 25

DEN
6h 50m
PHL

Jul 25

SYR

as low as

$588

, () - Syracuse, US (SYR)

American Airlines Logo
American Airlines

Jul 25

DEN
9h 21m
PHL

Jul 25

SYR

as low as

$588