$728 Business Class Flight Deals from Knoxville to Los Angeles

Top flight deals from leading airlines:

... and +100s more

Incredible Deals

Save up to 50% on select flights with Priceline

Bundle & Save

Save an average of $240 per person when bundling your flight and hotel together with Priceline

Best Price Guarantee

If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference

Help 24/7

We’re always here for you - reach us 24 hours a day, 7 days a week

Stops

Up to 2 stops
$1541

Airlines

Alaska Airlines
$4228
American Airlines
$1541

Cabin Class

First
$1541

Departure Airports

McGhee Tyson Airport
$1541

Arrival Airports

Bob Hope Airport
$4228
Los Angeles International Airport
$1541

Layover Airports

Charlotte Douglas International Airport
$1541
Chicago O Hare Airport
$1541
Dallas Fort Worth International Airport
$4228
Phoenix Sky Harbor International Airport
$1541
Seattle Tacoma International Airport
$4228

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

American Airlines

09/07/25

4:49pm

TYS

19h 2m

ORD

PHX

09/08/25

8:51am

LAX

American Airlines

09/14/25

6:00am

LAX

8h 36m

CLT

09/14/25

5:36pm

TYS

^$1541

Alaska Airlines

09/07/25

12:51pm

TYS

12h 8m

ORD

SEA

09/07/25

9:59pm

BUR

Alaska Airlines

09/14/25

7:00am

BUR

11h

SEA

ORD

09/14/25

9:00pm

TYS

^$4228

Alaska Airlines

09/07/25

5:30am

TYS

12h 56m

DFW

SEA

09/07/25

3:26pm

BUR

Alaska Airlines

09/14/25

7:00am

BUR

11h

SEA

ORD

09/14/25

9:00pm

TYS

^$4228

Alaska Airlines

09/07/25

7:30am

TYS

14h 11m

DFW

SEA

09/07/25

6:41pm

BUR

Alaska Airlines

09/14/25

7:00am

BUR

11h

SEA

ORD

09/14/25

9:00pm

TYS

^$4228

Alaska Airlines

09/07/25

12:51pm

TYS

12h 8m

ORD

SEA

09/07/25

9:59pm

BUR

Alaska Airlines

09/14/25

7:00am

BUR

13h 51m

SEA

DFW

09/14/25

11:51pm

TYS

^$4228

Alaska Airlines

09/07/25

7:14am

TYS

14h 27m

ORD

SEA

09/07/25

6:41pm

BUR

Alaska Airlines

09/14/25

7:00am

BUR

11h

SEA

ORD

09/14/25

9:00pm

TYS

^$4228

Alaska Airlines

09/07/25

5:30am

TYS

12h 56m

DFW

SEA

09/07/25

3:26pm

BUR

Alaska Airlines

09/14/25

7:00am

BUR

13h 51m

SEA

DFW

09/14/25

11:51pm

TYS

^$4228

Top Deals on flights Business Class from Knoxville to Los Angeles

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

8:23am

TYS

8h 51m

CLT

Sep 9

2:14pm

LAX

as low as

^$728

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

2:07pm

TYS

7h 23m

DFW

Sep 9

6:30pm

LAX

as low as

^$728

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

4:37pm

TYS

8h 56m

DFW

Sep 9

10:33pm

ONT

as low as

^$728

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

6:00am

TYS

7h 3m

DFW

Sep 9

10:03am

ONT

as low as

^$728

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

7:28am

TYS

9h 26m

DFW

Sep 9

1:54pm

ONT

as low as

^$728

Knoxville, US (TYS) - Burbank, US (BUR)

American Airlines

Sep 9

4:37pm

TYS

6h 59m

DFW

Sep 9

8:36pm

BUR

as low as

^$728

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

3:56pm

TYS

7h 9m

ORD

Sep 9

8:05pm

LAX

as low as

^$728

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

6:24pm

TYS

7h 9m

DFW

Sep 9

10:33pm

ONT

as low as

^$728

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

2:07pm

TYS

6h 22m

DFW

Sep 9

5:29pm

LAX

as low as

^$728

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

6:24pm

TYS

7h 11m

DFW

Sep 9

10:35pm

LAX

as low as

^$763

Knoxville, US (TYS) - , ()

American Airlines

Sep 9

6:00am

TYS

6h 32m

DFW

Sep 9

9:32am

SNA

as low as

^$843

Knoxville, US (TYS) - Los Angeles, US (LAX)

American Airlines

Sep 9

7:28am

TYS

8h 3m

DFW

Sep 9

12:31pm

LAX

as low as

^$844

Frequently Asked Questions

Is there a direct flight from Knoxville to Los Angeles?

There is no direct flight from Knoxville to Los Angeles. The available options are two-stop flights with American Airlines at $1541 and Alaska Airlines at $4228.

Are there convenient layover flights from Knoxville to Los Angeles?

Yes, convenient two-stop flights are available from Knoxville to Los Angeles. American Airlines offers a flight for $1541 with layovers in Chicago O'Hare and Phoenix Sky Harbor, taking 19 hours 2 minutes. Additionally, Alaska Airlines has a flight to Bob Hope Airport for $4228, with layovers in Chicago O'Hare and Seattle Tacoma, lasting 12 hours 8 minutes.

What are the most convenient layover airports for the flight?

The most convenient layover airports for your flight are Chicago O'Hare, Phoenix Sky Harbor, and Seattle Tacoma, featuring connections with American Airlines and Alaska Airlines.

What is the cheapest and fastest flight from Knoxville to Los Angeles?

The cheapest flight is with American Airlines for $1541, taking 19 hours 2 minutes. The fastest is with Alaska Airlines for $4228, taking 12 hours 8 minutes.

What are all possible destination arrival airports?

The possible destination arrival airports are Los Angeles International Airport and Bob Hope Airport.

What is the time difference between destination and arrival?

The time difference between Knoxville and Los Angeles is typically 2 hours, with Los Angeles being behind Knoxville. Ensure to adjust your schedule accordingly when planning your flight.

Flights to Los Angeles

Top Destinations

Origins

Return flights

Cabin Class

➔ Business Class Flights From Los Angeles To Knoxville

➔ Flights From Knoxville To Los Angeles

Business Class Flight Deals from Knoxville to Los Angeles from $728

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights Business Class from Knoxville to Los Angeles

Frequently Asked Questions

Flights to Los Angeles