$4782 Business Class Flight Deals from Cape Town to San Francisco

Top flight deals from leading airlines:

... and +100s more

Incredible Deals

Save up to 50% on select flights with Priceline

Bundle & Save

Save an average of $240 per person when bundling your flight and hotel together with Priceline

Best Price Guarantee

If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference

Help 24/7

We’re always here for you - reach us 24 hours a day, 7 days a week

Stops

Up to 1 stop
$7503
Up to 2 stops
$10727

Airlines

American Airlines
$8688
British Airways
$7503
Emirates
$8110
KLM
$10727
Qatar Airways
$7850
Singapore Airlines
$8804

Cabin Class

Business
$7503

Departure Airports

Cape Town International Airport
$7503

Arrival Airports

San Francisco International Airport
$7503

Layover Airports

Amsterdam Airport Schiphol
$10727
Dubai International Airport
$8110
Hamad International Airport
$7850
London Heathrow Airport
$7503
Paris Charles de Gaulle Airport
$10727
Singapore Changi Airport
$8804

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

Priceline Phone Deals

Book with an agent for great rates!

Call now!

1 (888) 775-6158

BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

British Airways

09/10/25

6:55pm

CPT

31h 30m

LHR

09/11/25

5:25pm

SFO

British Airways

09/17/25

4:30pm

SFO

33h 30m

LHR

09/19/25

11:00am

CPT

^$7503

British Airways

09/10/25

6:55pm

CPT

27h 55m

LHR

09/11/25

1:50pm

SFO

British Airways

09/17/25

4:30pm

SFO

33h 30m

LHR

09/19/25

11:00am

CPT

^$7503

Qatar Airways

09/10/25

1:00pm

CPT

33h 35m

DOH

09/11/25

1:35pm

SFO

Qatar Airways

09/17/25

3:55pm

SFO

33h 55m

DOH

09/19/25

10:50am

CPT

^$7850

Emirates

09/10/25

6:25pm

CPT

28h 35m

DXB

09/11/25

2:00pm

SFO

Emirates

09/17/25

5:05pm

SFO

33h 30m

DXB

09/19/25

11:35am

CPT

^$8110

Emirates

09/10/25

1:05pm

CPT

33h 55m

DXB

09/11/25

2:00pm

SFO

Emirates

09/17/25

5:05pm

SFO

33h 30m

DXB

09/19/25

11:35am

CPT

^$8110

American Airlines

09/10/25

6:55pm

CPT

27h 55m

LHR

09/11/25

1:50pm

SFO

American Airlines

09/17/25

4:30pm

SFO

33h 30m

LHR

09/19/25

11:00am

CPT

^$8688

American Airlines

09/10/25

6:55pm

CPT

31h 30m

LHR

09/11/25

5:25pm

SFO

American Airlines

09/17/25

4:30pm

SFO

33h 30m

LHR

09/19/25

11:00am

CPT

^$8688

Emirates

09/10/25

6:25pm

CPT

28h 35m

DXB

09/11/25

2:00pm

SFO

Emirates

09/17/25

5:05pm

SFO

38h 45m

DXB

09/19/25

4:50pm

CPT

^$8795

Emirates

09/10/25

1:05pm

CPT

33h 55m

DXB

09/11/25

2:00pm

SFO

Emirates

09/17/25

5:05pm

SFO

38h 45m

DXB

09/19/25

4:50pm

CPT

^$8795

Singapore Airlines

09/10/25

10:40am

CPT

32h

SIN

09/11/25

9:40am

SFO

Singapore Airlines

09/17/25

10:25pm

SFO

50h

SIN

09/20/25

9:25am

CPT

^$8804

Singapore Airlines

09/10/25

10:40am

CPT

32h

SIN

09/11/25

9:40am

SFO

Singapore Airlines

09/17/25

12:00pm

SFO

36h 25m

SIN

09/19/25

9:25am

CPT

^$8804

British Airways

09/10/25

6:55pm

CPT

31h 30m

LHR

09/11/25

5:25pm

SFO

British Airways

09/17/25

7:20pm

SFO

30h 40m

LHR

09/19/25

11:00am

CPT

^$8959

British Airways

09/10/25

6:55pm

CPT

27h 55m

LHR

09/11/25

1:50pm

SFO

British Airways

09/17/25

7:20pm

SFO

30h 40m

LHR

09/19/25

11:00am

CPT

^$8959

American Airlines

09/10/25

6:55pm

CPT

27h 55m

LHR

09/11/25

1:50pm

SFO

American Airlines

09/17/25

7:20pm

SFO

30h 40m

LHR

09/19/25

11:00am

CPT

^$10144

American Airlines

09/10/25

6:55pm

CPT

31h 30m

LHR

09/11/25

5:25pm

SFO

American Airlines

09/17/25

7:20pm

SFO

30h 40m

LHR

09/19/25

11:00am

CPT

^$10144

KLM

09/10/25

11:15pm

CPT

46h 35m

AMS

CDG

09/12/25

12:50pm

SFO

KLM

09/17/25

1:45pm

SFO

22h 40m

AMS

09/18/25

9:25pm

CPT

^$10727

KLM

09/10/25

11:15pm

CPT

45h 30m

AMS

09/12/25

11:45am

SFO

KLM

09/17/25

1:45pm

SFO

22h 40m

AMS

09/18/25

9:25pm

CPT

^$11557

KLM

09/10/25

11:15pm

CPT

29h 15m

AMS

LHR

09/11/25

7:30pm

SFO

KLM

09/17/25

1:45pm

SFO

22h 40m

AMS

09/18/25

9:25pm

CPT

^$11590

KLM

09/10/25

11:15pm

CPT

48h

AMS

LHR

09/12/25

2:15pm

SFO

KLM

09/17/25

1:45pm

SFO

22h 40m

AMS

09/18/25

9:25pm

CPT

^$12741

Top Deals on flights Business Class from Cape Town to San Francisco

Cape Town, ZA (CPT) - San Francisco, US (SFO)

Emirates

Sep 11

1:05pm

CPT

33h 55m

DXB

Sep 12

2:00pm

SFO

as low as

^$4782

Cape Town, ZA (CPT) - San Francisco, US (SFO)

Emirates

Sep 11

6:25pm

CPT

28h 35m

DXB

Sep 12

2:00pm

SFO

as low as

^$4782

Cape Town, ZA (CPT) - San Francisco, US (SFO)

Qatar Airways

Sep 11

1:00pm

CPT

33h 35m

DOH

Sep 12

1:35pm

SFO

as low as

^$4793

Cape Town, ZA (CPT) - San Francisco, US (SFO)

Singapore Airlines

Sep 11

10:40am

CPT

32h

SIN

Sep 12

9:40am

SFO

as low as

^$5298

Cape Town, ZA (CPT) - San Francisco, US (SFO)

American Airlines

Sep 11

6:55pm

CPT

31h 30m

LHR

Sep 12

5:25pm

SFO

as low as

^$7814

Cape Town, ZA (CPT) - San Francisco, US (SFO)

British Airways

Sep 11

6:55pm

CPT

27h 55m

LHR

Sep 12

1:50pm

SFO

as low as

^$7828

Cape Town, ZA (CPT) - San Francisco, US (SFO)

KLM

Sep 11

11:15pm

CPT

45h 30m

AMS

Sep 13

11:45am

SFO

as low as

^$10083

Cape Town, ZA (CPT) - San Francisco, US (SFO)

KLM

Sep 11

11:15pm

CPT

29h 15m

AMS

LHR

Sep 12

7:30pm

SFO

as low as

^$10117

Cape Town, ZA (CPT) - San Francisco, US (SFO)

KLM

Sep 11

11:15pm

CPT

46h 35m

AMS

CDG

Sep 13

12:50pm

SFO

as low as

^$10127

Cape Town, ZA (CPT) - San Francisco, US (SFO)

American Airlines

Sep 11

6:55pm

CPT

27h 55m

LHR

Sep 12

1:50pm

SFO

as low as

^$11334

Cape Town, ZA (CPT) - San Francisco, US (SFO)

British Airways

Sep 11

6:55pm

CPT

31h 30m

LHR

Sep 12

5:25pm

SFO

as low as

^$11348

Frequently Asked Questions

Are there convenient layover flights from Cape Town to San Francisco?

Yes, convenient layover flights from Cape Town to San Francisco include British Airways at $7503, Qatar Airways at $7850, Emirates at $8110, American Airlines at $8688, and Singapore Airlines at $8804. A 2-stop option is available with KLM at $10727.

What are the most convenient layover airports for a flight from Cape Town to San Francisco?

The most convenient layover airports for your flight are London Heathrow, Hamad International, Dubai International, and Singapore Changi.

What is the cheapest and fastest flight from Cape Town to San Francisco?

The cheapest flight is with British Airways for $7503, taking 27 hours 55 minutes. No faster option exists.

What are all possible destination arrival airports?

The possible destination arrival airports are San Francisco International Airport, London Heathrow Airport, Hamad International Airport, Dubai International Airport, Singapore Changi Airport, Amsterdam Airport Schiphol, and Paris Charles de Gaulle Airport.

What is the time difference between destination and arrival?

The time difference between Cape Town and San Francisco is 10 hours, with Cape Town ahead of San Francisco.

Is there a direct flight from Cape Town to San Francisco?

There is no direct flight from Cape Town International Airport to San Francisco International Airport. The cheapest available flight is a 1 stop with British Airways at $7503.