Check Availability

Comfort Inn & Suites Sikeston Hotel

109 Matthews Lane, Sikeston, MO

Comfort Inn & Suites Sikeston

With a free full breakfast, an indoor pool and in-room microwaves and refrigerators, the Comfort Inn & Suites Sikeston is located conveniently close to shopping, the interstate and many area attractions.

Guest Score and Reviews

Based on 41 reviews | All reviews are from verified hotel guests

    Check Availability

    Comfort Inn & Suites Sikeston Hotel

    This three-story hotel has 64 rooms, some of which are designated non-smoking. Pets are allowed for a fee. Each room includes a mini-fridge, microwave, coffeemaker, flat-panel cable TV, hairdryer, iron and ironing board. Guests enjoy a complimentary full breakfast each morning. There is an indoor pool, a hot tub and an on-site exercise room. Laundry facilities and Wi-Fi access are also available for guests' convenience.
    Get the best deals without needing a promo code! Save on your reservation by booking with our discount rates at
    Comfort Inn & Suites Sikeston Hotel in MO

    Hotel Location

    The Comfort Inn is a half-mile from Lambert's Cafe, home of the famous throwed rolls, and Sikeston Factory Outlet Mall. Drive four miles for entertainment at the Jaycee Bootheel Rodeo. Beggs Family Farm is a 15-minute drive, and Orgill Inc. is 10 minutes away. Sikeston Memorial Municipal Airport is three miles from the hotel, and it's 27 miles to Cape Girardeau Regional Airport.
    109 Matthews Lane
    Sikeston, Missouri
    63801, United States

    Hotel Amenities

    WiFi Available in All Areas
    Non-smoking Rooms

    Hotel Policies

    Check in
    2:00 PM
    Check out
    11:00 AM

    Important Information

    You must show a valid photo ID and credit card upon check-in. Guests are required to show a photo identification and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.