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Flight Deals to Santa Cruz from $578

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Bundle + Save

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Incredible Deals

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Up to 1 stop
    $1178
  • Up to 2 stops
    $648

Airlines

  • Alaska Airlines
    $1870
  • AVIANCA
    $1033
  • Boliviana de Aviacion - BoA
    $1068
  • COPA Airlines
    $1064
  • Gol Transportes Aéreos
    $999
  • LATAM Airlines Group
    $1086
  • TACA
    $850
  • United Airlines
    $648

Cabin Class

  • Economy
    $648

Departure Airports

  • Los Angeles International Airport
    $648
  • Ontario International Airport
    $697

Arrival Airports

  • Viru Viru International Airport
    $648

Layover Airports

  • Buenos Aires Ministro Pistarini Airport
    $1064
  • Comodoro Arturo Merino Benítez International Airport
    $1086
  • Dallas Fort Worth International Airport
    $1876
  • Denver International Airport
    $1496
  • El Alto International Airport
    $1393
  • El Dorado International Airport
    $697
  • George Bush Intercontinental Houston Airport
    $648
  • Hartsfield Jackson Atlanta International Airport
    $1272
  • Jorge Chávez International Airport
    $1086
  • Juan Santamaria International Airport
    $2328
  • La Aurora Airport
    $850
  • Licenciado Benito Juarez International Airport
    $1285
  • Miami International Airport
    $1876
  • Monseñor Óscar Arnulfo Romero International Airport
    $1033
  • New York John F Kennedy Airport
    $1596
  • Newark Liberty Airport
    $1494
  • San Francisco International Airport
    $1161
  • Sao Paulo Guarulhos Airport
    $648
  • Tocumen International Airport
    $648

Best Price. GUARANTEED.

Exclusively for Priceline Members
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BUNDLE & SAVE

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On average save $240 per traveler
United Airlines Logo
United Airlines

05/07/25

LAX
21h 45m
IAH
GRU

05/08/25

VVI
United Airlines Logo
United Airlines

05/11/25

VVI
18h 54m
PTY
IAH

05/11/25

LAX
$648
Free cancellation within 83 hours of booking
United Airlines Logo
United Airlines

05/02/25

ONT
32h 28m
IAH
PTY

05/03/25

VVI
United Airlines Logo
United Airlines

05/24/25

VVI
14h 1m
BOG
IAH

05/24/25

ONT
$697
Free cancellation within 83 hours of booking
TACA Logo
TACA

05/02/25

LAX
35h
GUA
BOG

05/04/25

VVI
TACA Logo
TACA

05/24/25

VVI
33h 5m
BOG
GUA

05/25/25

LAX
$850
Free cancellation within 83 hours of booking
Gol Transportes Aéreos Logo
Gol Transportes Aéreos

05/04/25

LAX
29h 18m
IAH
GRU

05/05/25

VVI
Gol Transportes Aéreos Logo
Gol Transportes Aéreos

05/06/25

VVI
20h 51m
PTY
IAH

05/06/25

LAX
$999
Free cancellation within 83 hours of booking
AVIANCA Logo
AVIANCA

05/02/25

LAX
25h 20m
SAL
BOG

05/03/25

VVI
AVIANCA Logo
AVIANCA

05/24/25

VVI
19h 35m
BOG
SAL

05/24/25

LAX
$1033
Free cancellation within 83 hours of booking
COPA Airlines Logo
COPA Airlines

05/02/25

LAX
26h 44m
PTY
EZE

05/03/25

VVI
COPA Airlines Logo
COPA Airlines

05/24/25

VVI
19h 35m
BOG
SAL

05/24/25

LAX
$1064
Free cancellation within 83 hours of booking
Boliviana de Aviacion - BoA Logo
Boliviana de Aviacion - BoA

05/02/25

LAX
26h 44m
PTY
EZE

05/03/25

VVI
Boliviana de Aviacion - BoA Logo
Boliviana de Aviacion - BoA

05/24/25

VVI
20h 15m
BOG
SAL

05/24/25

LAX
$1068
Free cancellation within 83 hours of booking
LATAM Airlines Group Logo
LATAM Airlines Group

05/05/25

LAX
36h 20m
SCL
LIM

05/07/25

VVI
LATAM Airlines Group Logo
LATAM Airlines Group

05/07/25

VVI
22h 33m
SCL

05/08/25

LAX
$1086
Free cancellation within 83 hours of booking
COPA Airlines Logo
COPA Airlines

05/02/25

LAX
25h 24m
PTY

05/03/25

VVI
COPA Airlines Logo
COPA Airlines

05/24/25

VVI
34h 30m
PTY
SFO

05/25/25

LAX
$1161
Free cancellation within 83 hours of booking
United Airlines Logo
United Airlines

05/07/25

LAX
20h 3m
PTY

05/07/25

VVI
United Airlines Logo
United Airlines

05/11/25

VVI
15h 50m
PTY

05/11/25

LAX
$1178
Free cancellation within 83 hours of booking
LATAM Airlines Group Logo
LATAM Airlines Group

05/05/25

LAX
38h 20m
ATL
LIM

05/07/25

VVI
LATAM Airlines Group Logo
LATAM Airlines Group

05/12/25

VVI
18h 9m
LIM
ATL

05/12/25

LAX
$1272
Free cancellation within 83 hours of booking
LATAM Airlines Group Logo
LATAM Airlines Group

05/07/25

LAX
33h 50m
MEX
LIM

05/09/25

VVI
LATAM Airlines Group Logo
LATAM Airlines Group

05/11/25

VVI
13h 35m
LIM

05/11/25

LAX
$1285
Free cancellation within 83 hours of booking
LATAM Airlines Group Logo
LATAM Airlines Group

05/04/25

LAX
31h 10m
LIM

05/06/25

VVI
LATAM Airlines Group Logo
LATAM Airlines Group

05/06/25

VVI
20h 55m
LPB
LIM

05/07/25

LAX
$1393
Free cancellation within 83 hours of booking
Gol Transportes Aéreos Logo
Gol Transportes Aéreos

05/05/25

LAX
23h 59m
PTY

05/06/25

VVI
Gol Transportes Aéreos Logo
Gol Transportes Aéreos

05/12/25

VVI
25h 35m
GRU
EWR

05/13/25

LAX
$1494
Free cancellation within 83 hours of booking
Gol Transportes Aéreos Logo
Gol Transportes Aéreos

05/05/25

ONT
29h 58m
DEN
PTY

05/06/25

VVI
Gol Transportes Aéreos Logo
Gol Transportes Aéreos

05/12/25

VVI
25h 35m
GRU
EWR

05/13/25

ONT
$1496
Free cancellation within 83 hours of booking
LATAM Airlines Group Logo
LATAM Airlines Group

05/07/25

LAX
38h 12m
ATL
LIM

05/09/25

VVI
LATAM Airlines Group Logo
LATAM Airlines Group

05/11/25

VVI
28h 40m
LIM
JFK

05/12/25

LAX
$1596
Free cancellation within 83 hours of booking
Alaska Airlines Logo
Alaska Airlines

05/05/25

LAX
28h 25m
GUA
PTY

05/06/25

VVI
Alaska Airlines Logo
Alaska Airlines

05/12/25

VVI
24h 38m
PTY

05/13/25

LAX
$1870
Free cancellation within 83 hours of booking
Gol Transportes Aéreos Logo
Gol Transportes Aéreos

05/07/25

LAX
22h 45m
DFW
GRU

05/08/25

VVI
Gol Transportes Aéreos Logo
Gol Transportes Aéreos

05/11/25

VVI
21h 44m
GRU
MIA

05/12/25

LAX
$1876
Free cancellation within 83 hours of booking
Alaska Airlines Logo
Alaska Airlines

05/02/25

LAX
28h 58m
SJO
PTY

05/03/25

VVI
Alaska Airlines Logo
Alaska Airlines

05/24/25

VVI
18h 14m
PTY
SJO

05/25/25

LAX
$2328
Free cancellation within 83 hours of booking

Top Deals on flights to Santa Cruz

Dallas, US (DFW) - Santa Cruz, BO (SRZ)

AVIANCA Logo
AVIANCA

Jun 15

DFW
16h 35m
BOG
LPB

Jun 16

VVI

as low as

$578

Dallas, US (DFW) - Santa Cruz, BO (SRZ)

AVIANCA Logo
AVIANCA

May 31

DFW
36h
SAL
BOG

Jun 2

VVI

as low as

$843

Dallas, US (DFW) - Santa Cruz, BO (SRZ)

Gol Transportes Aéreos Logo
Gol Transportes Aéreos

May 19

DFW
26h 6m
MIA
GRU

May 20

VVI

as low as

$889

Dallas, US (DFW) - Santa Cruz, BO (SRZ)

Gol Transportes Aéreos Logo
Gol Transportes Aéreos

May 17

DFW
15h 49m
GRU

May 18

VVI

as low as

$933

Dallas, US (DFW) - Santa Cruz, BO (SRZ)

 Logo

Jun 16

DFW
26h 13m
YYZ
PTY

Jun 17

VVI

as low as

$970

Dallas, US (DFW) - Santa Cruz, BO (SRZ)

LATAM Airlines Group Logo
LATAM Airlines Group

May 29

DFW
22h 25m
LAX
LIM

May 30

VVI

as low as

$983

Dallas, US (DFW) - Santa Cruz, BO (SRZ)

 Logo

May 31

DFW
27h 31m
LHR
MAD

Jun 2

VVI

as low as

$2129

Dallas, US (DFW) - Santa Cruz, BO (SRZ)

United Airlines Logo
United Airlines

May 29

DFW
30h 18m
IAH
BOG

May 31

VVI

as low as

$2402

Dallas, US (DFW) - Santa Cruz, BO (SRZ)

Boliviana de Aviacion - BoA Logo
Boliviana de Aviacion - BoA

May 19

DFW
29h 43m
SJU
MIA

May 21

VVI

as low as

$2710

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