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Flight Deals to Prague from $446

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Up to 1 stop
    $598
  • Up to 2 stops
    $639

Airlines

  • Aer Lingus
    $793
  • Air Canada
    $667
  • Air France
    $928
  • American Airlines
    $920
  • Austrian Airlines
    $699
  • British Airways
    $700
  • Brussels Airlines
    $757
  • Condor
    $1098
  • Icelandair
    $807
  • JetBlue
    $1123
  • KLM
    $998
  • LOT Polish Airlines
    $1003
  • Lufthansa
    $685
  • SAS Airlines
    $639
  • SWISS
    $694
  • TAP Portugal
    $895
  • Turkish Airlines
    $598

Cabin Class

  • Economy
    $598

Departure Airports

  • Detroit Metropolitan Airport
    $598

Arrival Airports

  • Václav Havel Airport Prague
    $598

Layover Airports

  • Amsterdam Airport Schiphol
    $998
  • Belgrade Nikola Tesla Airport
    $1123
  • Brussels Airport
    $709
  • Charlotte Douglas International Airport
    $876
  • Chicago O Hare Airport
    $689
  • Copenhagen Kastrup Airport
    $639
  • Dublin Airport
    $793
  • Frankfurt am Main Airport
    $667
  • General Edward Lawrence Logan International Airport
    $639
  • Helsinki Vantaa Airport
    $1129
  • Humberto Delgado Airport (Lisbon Portela Airport)
    $895
  • Istanbul Airport
    $598
  • London Heathrow Airport
    $700
  • Montreal Trudeau Airport
    $667
  • Munich Airport
    $693
  • New York John F Kennedy Airport
    $807
  • Newark Liberty Airport
    $693
  • Paris Charles de Gaulle Airport
    $928
  • Philadelphia International Airport
    $700
  • Reykjavik Keflavik Airport
    $807
  • Toronto Pearson Airport
    $674
  • Vienna International Airport
    $699
  • Warsaw Chopin Airport
    $1003
  • Washington Dulles Airport
    $707
  • Zürich Airport
    $667

Best Price. GUARANTEED.

Exclusively for Priceline Members
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BUNDLE & SAVE

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On average save $240 per traveler
Turkish Airlines Logo
Turkish Airlines

10/21/25

DTW
21h 25m
IST

10/22/25

PRG
Turkish Airlines Logo
Turkish Airlines

10/28/25

PRG
28h 25m
IST

10/29/25

DTW
$598
Free cancellation within 83 hours of booking
Turkish Airlines Logo
Turkish Airlines

10/15/25

DTW
21h 25m
IST

10/16/25

PRG
Turkish Airlines Logo
Turkish Airlines

10/22/25

PRG
27h 40m
IST

10/23/25

DTW
$598
Free cancellation within 83 hours of booking
SAS Airlines Logo
SAS Airlines

10/21/25

DTW
19h 55m
BOS
CPH

10/22/25

PRG
SAS Airlines Logo
SAS Airlines

10/28/25

PRG
11h 39m
CPH
BOS

10/28/25

DTW
$639
Free cancellation within 83 hours of booking
Air Canada Logo
Air Canada

09/30/25

DTW
23h 10m
YUL
ZRH

10/01/25

PRG
Air Canada Logo
Air Canada

10/22/25

PRG
15h 29m
FRA
YUL

10/22/25

DTW
$667
Free cancellation within 83 hours of booking
Air Canada Logo
Air Canada

09/29/25

DTW
23h 10m
YUL
ZRH

09/30/25

PRG
Air Canada Logo
Air Canada

10/07/25

PRG
15h 29m
FRA
YUL

10/07/25

DTW
$667
Free cancellation within 83 hours of booking
Air Canada Logo
Air Canada

10/03/25

DTW
23h 10m
YUL
ZRH

10/04/25

PRG
Air Canada Logo
Air Canada

10/10/25

PRG
9h 37m
FRA
YYZ

10/10/25

DTW
$674
Free cancellation within 83 hours of booking
Lufthansa Logo
Lufthansa

10/15/25

DTW
17h 40m
FRA

10/16/25

PRG
Lufthansa Logo
Lufthansa

10/22/25

PRG
9h 37m
FRA
YYZ

10/22/25

DTW
$685
Free cancellation within 83 hours of booking
Lufthansa Logo
Lufthansa

10/15/25

DTW
19h 30m
ORD
FRA

10/16/25

PRG
Lufthansa Logo
Lufthansa

10/22/25

PRG
9h 37m
FRA
YYZ

10/22/25

DTW
$689
Free cancellation within 83 hours of booking
Lufthansa Logo
Lufthansa

10/07/25

DTW
20h 20m
EWR
MUC

10/08/25

PRG
Lufthansa Logo
Lufthansa

10/14/25

PRG
8h 10m
FRA

10/14/25

DTW
$693
Free cancellation within 83 hours of booking
SWISS Logo
SWISS

10/15/25

DTW
23h 55m
ORD
ZRH

10/16/25

PRG
SWISS Logo
SWISS

10/21/25

PRG
10h 26m
ZRH
ORD

10/21/25

DTW
$694
Free cancellation within 83 hours of booking
SWISS Logo
SWISS

10/07/25

DTW
23h 55m
ORD
ZRH

10/08/25

PRG
SWISS Logo
SWISS

10/14/25

PRG
10h 26m
ZRH
ORD

10/14/25

DTW
$694
Free cancellation within 83 hours of booking
Austrian Airlines Logo
Austrian Airlines

10/21/25

DTW
20h 25m
ORD
VIE

10/22/25

PRG
Austrian Airlines Logo
Austrian Airlines

10/28/25

PRG
7h 35m
FRA

10/28/25

DTW
$699
Free cancellation within 83 hours of booking
British Airways Logo
British Airways

10/15/25

DTW
36h 27m
ORD
LHR

10/17/25

PRG
British Airways Logo
British Airways

10/22/25

PRG
13h 42m
LHR
ORD

10/22/25

DTW
$700
Free cancellation within 83 hours of booking
British Airways Logo
British Airways

10/07/25

DTW
26h 42m
ORD
LHR

10/08/25

PRG
British Airways Logo
British Airways

10/14/25

PRG
13h 47m
LHR
PHL

10/14/25

DTW
$700
Free cancellation within 83 hours of booking
Lufthansa Logo
Lufthansa

10/04/25

DTW
19h 10m
IAD
FRA

10/05/25

PRG
Lufthansa Logo
Lufthansa

10/13/25

PRG
8h 10m
FRA

10/13/25

DTW
$707
Free cancellation within 83 hours of booking
Lufthansa Logo
Lufthansa

09/30/25

DTW
19h 10m
IAD
FRA

10/01/25

PRG
Lufthansa Logo
Lufthansa

10/17/25

PRG
8h 10m
FRA

10/17/25

DTW
$707
Free cancellation within 83 hours of booking
Lufthansa Logo
Lufthansa

10/21/25

DTW
18h 45m
ORD
MUC

10/22/25

PRG
Lufthansa Logo
Lufthansa

10/28/25

PRG
16h 47m
BRU
ORD

10/28/25

DTW
$709
Free cancellation within 83 hours of booking
Brussels Airlines Logo
Brussels Airlines

10/15/25

DTW
25h 35m
YYZ
BRU

10/16/25

PRG
Brussels Airlines Logo
Brussels Airlines

10/22/25

PRG
8h 10m
FRA

10/22/25

DTW
$757
Free cancellation within 83 hours of booking
Aer Lingus Logo
Aer Lingus

10/07/25

DTW
24h
BOS
DUB

10/08/25

PRG
Aer Lingus Logo
Aer Lingus

10/14/25

PRG
11h 1m
DUB
PHL

10/14/25

DTW
$793
Free cancellation within 83 hours of booking
Icelandair Logo
Icelandair

09/30/25

DTW
16h 35m
KEF

10/01/25

PRG
Icelandair Logo
Icelandair

10/17/25

PRG
20h 25m
KEF
BOS

10/18/25

DTW
$807
Free cancellation within 83 hours of booking
Icelandair Logo
Icelandair

10/16/25

DTW
16h 35m
KEF

10/17/25

PRG
Icelandair Logo
Icelandair

10/22/25

PRG
9h 35m
KEF
JFK

10/22/25

DTW
$807
Free cancellation within 83 hours of booking
British Airways Logo
British Airways

10/15/25

DTW
23h 52m
ORD
LHR

10/16/25

PRG
British Airways Logo
British Airways

10/22/25

PRG
11h 24m
LHR
CLT

10/22/25

DTW
$876
Free cancellation within 83 hours of booking
TAP Portugal Logo
TAP Portugal

10/15/25

DTW
25h
BOS
LIS

10/16/25

PRG
TAP Portugal Logo
TAP Portugal

10/22/25

PRG
30h 22m
LIS
BOS

10/23/25

DTW
$895
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

10/01/25

DTW
24h 43m
CLT
LHR

10/02/25

PRG
American Airlines Logo
American Airlines

11/01/25

PRG
12h 47m
LHR
PHL

11/01/25

DTW
$920
Free cancellation within 83 hours of booking
Air France Logo
Air France

10/04/25

DTW
24h 25m
CDG

10/05/25

PRG
Air France Logo
Air France

10/10/25

PRG
22h 40m
CDG

10/11/25

DTW
$928
Free cancellation within 83 hours of booking
KLM Logo
KLM

09/30/25

DTW
20h 20m
CDG
AMS

10/01/25

PRG
KLM Logo
KLM

10/22/25

PRG
13h 5m
AMS
CDG

10/22/25

DTW
$998
Free cancellation within 83 hours of booking
LOT Polish Airlines Logo
LOT Polish Airlines

10/15/25

DTW
30h 5m
JFK
WAW

10/16/25

PRG
LOT Polish Airlines Logo
LOT Polish Airlines

10/21/25

PRG
16h 25m
WAW
JFK

10/21/25

DTW
$1003
Free cancellation within 83 hours of booking
Condor Logo
Condor

10/07/25

DTW
23h 35m
BOS
FRA

10/08/25

PRG
Condor Logo
Condor

10/14/25

PRG
11h 12m
FRA
BOS

10/14/25

DTW
$1098
Free cancellation within 83 hours of booking
JetBlue Logo
JetBlue

10/18/25

DTW
31h 50m
JFK
BEG

10/19/25

PRG
JetBlue Logo
JetBlue

10/24/25

PRG
14h 20m
BEG
JFK

10/24/25

DTW
$1123
Free cancellation within 83 hours of booking
Icelandair Logo
Icelandair

10/07/25

DTW
16h 35m
KEF

10/08/25

PRG
Icelandair Logo
Icelandair

10/14/25

PRG
11h 10m
HEL
KEF

10/14/25

DTW
$1129
Free cancellation within 83 hours of booking

Top Deals on flights to Prague

, () - Prague, CZ (PRG)

American Airlines Logo
American Airlines

Sep 3

LAX
24h 40m
LHR

Sep 4

PRG

as low as

$446

, () - Prague, CZ (PRG)

American Airlines Logo
American Airlines

Sep 3

LAX
29h 26m
PHX
LHR

Sep 4

PRG

as low as

$450

, () - Prague, CZ (PRG)

IBERIA Logo
IBERIA

Sep 3

LAX
30h
LHR

Sep 4

PRG

as low as

$451

, () - Prague, CZ (PRG)

IBERIA Logo
IBERIA

Oct 12

LAX
38h 20m
BCN

Oct 14

PRG

as low as

$457

, () - Prague, CZ (PRG)

 Logo

Sep 3

LAX
42h 30m
BCN

Sep 5

PRG

as low as

$459

, () - Prague, CZ (PRG)

British Airways Logo
British Airways

Jul 22

LAX
23h 20m
LHR

Jul 23

PRG

as low as

$461

, () - Prague, CZ (PRG)

Finnair Logo
Finnair

Sep 3

LAX
27h
LHR

Sep 4

PRG

as low as

$472

, () - Prague, CZ (PRG)

Aer Lingus Logo
Aer Lingus

Aug 12

LAX
29h 5m
ORD
DUB

Aug 13

PRG

as low as

$485

, () - Prague, CZ (PRG)

 Logo

Sep 3

LAX
24h
JFK

Sep 4

PRG

as low as

$487

, () - Prague, CZ (PRG)

SAS Airlines Logo
SAS Airlines

Sep 28

LAX
24h 35m
CPH

Sep 29

PRG

as low as

$487

, () - Prague, CZ (PRG)

Air Canada Logo
Air Canada

Aug 11

LAX
38h 15m
YYZ

Aug 13

PRG

as low as

$489

, () - Prague, CZ (PRG)

Air Canada Logo
Air Canada

Aug 8

LAX
61h 40m
YUL
YYZ

Aug 11

PRG

as low as

$489

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