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Flight Deals from Syracuse to Santo Domingo from $204

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Stops

  • Up to 1 stop
    $432
  • Up to 2 stops
    $464

Airlines

  • American Airlines
    $557
  • JetBlue
    $432
  • United Airlines
    $532

Cabin Class

  • Economy
    $432

Departure Airports

  • Syracuse Hancock International Airport
    $432

Arrival Airports

  • Las Américas International Airport
    $432

Layover Airports

  • Charlotte Douglas International Airport
    $557
  • Chicago O Hare Airport
    $536
  • Fort Lauderdale Hollywood International Airport
    $464
  • General Edward Lawrence Logan International Airport
    $484
  • Luis Munoz Marin International Airport
    $489
  • Miami International Airport
    $557
  • New York John F Kennedy Airport
    $432
  • Newark Liberty Airport
    $532
  • Orlando International Airport
    $432
  • Philadelphia International Airport
    $557
  • Reagan Washington National Airport
    $557
  • Washington Dulles Airport
    $536

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Exclusively for Priceline Members
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BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
JetBlue Logo
JetBlue

09/13/25

SYR
7h 54m
MCO

09/13/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
8h 53m
JFK

09/20/25

SYR
$432
JetBlue Logo
JetBlue

09/13/25

SYR
7h 54m
MCO

09/13/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
15h 46m
JFK

09/20/25

SYR
$433
JetBlue Logo
JetBlue

09/13/25

SYR
16h 52m
JFK

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
8h 53m
JFK

09/20/25

SYR
$433
JetBlue Logo
JetBlue

09/13/25

SYR
16h 52m
JFK

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
15h 46m
JFK

09/20/25

SYR
$434
JetBlue Logo
JetBlue

09/13/25

SYR
7h 54m
MCO

09/13/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
18h 21m
JFK

09/20/25

SYR
$441
JetBlue Logo
JetBlue

09/13/25

SYR
7h 54m
MCO

09/13/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
11h 6m
JFK

09/20/25

SYR
$443
JetBlue Logo
JetBlue

09/13/25

SYR
30h 9m
JFK
FLL

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
8h 53m
JFK

09/20/25

SYR
$464
JetBlue Logo
JetBlue

09/13/25

SYR
30h 9m
JFK
FLL

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
15h 46m
JFK

09/20/25

SYR
$465
JetBlue Logo
JetBlue

09/13/25

SYR
20h 5m
BOS
JFK

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
8h 53m
JFK

09/20/25

SYR
$484
JetBlue Logo
JetBlue

09/13/25

SYR
18h 7m
BOS
JFK

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
8h 53m
JFK

09/20/25

SYR
$484
JetBlue Logo
JetBlue

09/13/25

SYR
18h 7m
BOS
JFK

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
15h 46m
JFK

09/20/25

SYR
$485
JetBlue Logo
JetBlue

09/13/25

SYR
20h 5m
BOS
JFK

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
15h 46m
JFK

09/20/25

SYR
$485
JetBlue Logo
JetBlue

09/13/25

SYR
7h 54m
MCO

09/13/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
14h 11m
SJU
JFK

09/20/25

SYR
$489
JetBlue Logo
JetBlue

09/13/25

SYR
16h 52m
JFK

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
14h 11m
SJU
JFK

09/20/25

SYR
$490
JetBlue Logo
JetBlue

09/13/25

SYR
28h 7m
JFK

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
14h 11m
SJU
JFK

09/20/25

SYR
$499
JetBlue Logo
JetBlue

09/13/25

SYR
18h 50m
JFK

09/14/25

SDQ
JetBlue Logo
JetBlue

09/20/25

SDQ
14h 11m
SJU
JFK

09/20/25

SYR
$499
United Airlines Logo
United Airlines

09/13/25

SYR
8h 10m
EWR

09/13/25

SDQ
United Airlines Logo
United Airlines

09/20/25

SDQ
17h 14m
EWR

09/20/25

SYR
$532
United Airlines Logo
United Airlines

09/13/25

SYR
8h 10m
EWR

09/13/25

SDQ
United Airlines Logo
United Airlines

09/20/25

SDQ
7h 39m
EWR

09/20/25

SYR
$532
United Airlines Logo
United Airlines

09/13/25

SYR
16h 7m
IAD
EWR

09/14/25

SDQ
United Airlines Logo
United Airlines

09/20/25

SDQ
15h 20m
EWR
ORD

09/20/25

SYR
$536
United Airlines Logo
United Airlines

09/13/25

SYR
19h 30m
ORD
EWR

09/14/25

SDQ
United Airlines Logo
United Airlines

09/20/25

SDQ
7h 39m
EWR

09/20/25

SYR
$536
United Airlines Logo
United Airlines

09/13/25

SYR
16h 7m
IAD
EWR

09/14/25

SDQ
United Airlines Logo
United Airlines

09/20/25

SDQ
11h 1m
EWR
ORD

09/20/25

SYR
$536
United Airlines Logo
United Airlines

09/13/25

SYR
18h 22m
IAD
EWR

09/14/25

SDQ
United Airlines Logo
United Airlines

09/20/25

SDQ
18h 24m
EWR
IAD

09/21/25

SYR
$536
American Airlines Logo
American Airlines

09/13/25

SYR
12h 30m
PHL
MIA

09/13/25

SDQ
American Airlines Logo
American Airlines

09/20/25

SDQ
18h 48m
MIA
ORD

09/21/25

SYR
$557
American Airlines Logo
American Airlines

09/13/25

SYR
8h 17m
CLT
MIA

09/13/25

SDQ
American Airlines Logo
American Airlines

09/20/25

SDQ
18h 48m
MIA
ORD

09/21/25

SYR
$557
American Airlines Logo
American Airlines

09/13/25

SYR
13h 27m
CLT
MIA

09/13/25

SDQ
American Airlines Logo
American Airlines

09/20/25

SDQ
18h 48m
MIA
ORD

09/21/25

SYR
$557
American Airlines Logo
American Airlines

09/13/25

SYR
9h 10m
PHL
MIA

09/13/25

SDQ
American Airlines Logo
American Airlines

09/20/25

SDQ
18h 48m
MIA
ORD

09/21/25

SYR
$557
American Airlines Logo
American Airlines

09/13/25

SYR
14h 58m
DCA
MIA

09/13/25

SDQ
American Airlines Logo
American Airlines

09/20/25

SDQ
18h 48m
MIA
ORD

09/21/25

SYR
$557
American Airlines Logo
American Airlines

09/13/25

SYR
9h 48m
DCA
MIA

09/13/25

SDQ
American Airlines Logo
American Airlines

09/20/25

SDQ
18h 48m
MIA
ORD

09/21/25

SYR
$557
American Airlines Logo
American Airlines

09/13/25

SYR
14h 20m
PHL
MIA

09/13/25

SDQ
American Airlines Logo
American Airlines

09/20/25

SDQ
18h 48m
MIA
ORD

09/21/25

SYR
$557
American Airlines Logo
American Airlines

09/13/25

SYR
9h 10m
PHL
MIA

09/13/25

SDQ
American Airlines Logo
American Airlines

09/20/25

SDQ
10h 9m
MIA
DCA

09/20/25

SYR
$597

Top Deals on flights from Syracuse to Santo Domingo

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

JetBlue Logo
JetBlue

Sep 13

SYR
7h 54m
MCO

Sep 13

SDQ

as low as

$204

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

JetBlue Logo
JetBlue

Sep 13

SYR
28h 7m
JFK

Sep 14

SDQ

as low as

$219

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

JetBlue Logo
JetBlue

Sep 13

SYR
16h 52m
JFK

Sep 14

SDQ

as low as

$224

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

JetBlue Logo
JetBlue

Sep 13

SYR
30h 9m
JFK
FLL

Sep 14

SDQ

as low as

$242

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

United Airlines Logo
United Airlines

Sep 13

SYR
18h 12m
ORD
EWR

Sep 14

SDQ

as low as

$254

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

United Airlines Logo
United Airlines

Sep 13

SYR
8h 10m
EWR

Sep 13

SDQ

as low as

$254

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

United Airlines Logo
United Airlines

Sep 13

SYR
19h 30m
ORD
EWR

Sep 14

SDQ

as low as

$254

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

United Airlines Logo
United Airlines

Sep 13

SYR
16h 7m
IAD
EWR

Sep 14

SDQ

as low as

$254

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

JetBlue Logo
JetBlue

Sep 13

SYR
24h 19m
MCO

Sep 14

SDQ

as low as

$254

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

United Airlines Logo
United Airlines

Sep 13

SYR
18h 22m
IAD
EWR

Sep 14

SDQ

as low as

$260

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

JetBlue Logo
JetBlue

Sep 13

SYR
27h 4m
BOS

Sep 14

SDQ

as low as

$264

Syracuse, US (SYR) - Santo Domingo, DO (SDQ)

American Airlines Logo
American Airlines

Sep 13

SYR
14h 58m
DCA
MIA

Sep 13

SDQ

as low as

$265

Frequently Asked Questions

What are all possible destination arrival airports?
The possible arrival airports are Las Américas International Airport, Orlando International Airport, New York John F Kennedy Airport, Newark Liberty Airport, Fort Lauderdale Hollywood International Airport, Washington Dulles Airport, Philadelphia International Airport, and Miami International Airport.
What is the time difference between destination and arrival?
The time difference between Syracuse, NY, and Santo Domingo, Dominican Republic, is typically one hour, with Santo Domingo being one hour ahead of Syracuse.
Is there a direct flight from Syracuse to Santo Domingo?
There is no direct flight from Syracuse to Santo Domingo. The available options include 1 stop flights with JetBlue starting at $432, and United Airlines at $532.
Are there convenient layover flights from Syracuse to Santo Domingo?
Yes, there are convenient layover flights from Syracuse to Santo Domingo. JetBlue offers a 1 stop flight for $432 (7h 54m) via Orlando. United Airlines has a 1 stop flight for $532 (8h 10m) via Newark. Two stop options include JetBlue for $464 and United for $536.
What are the most convenient layover airports for the flight?
The most convenient layover airports for your flight from Syracuse to Santo Domingo include Orlando International Airport, New York John F Kennedy Airport, Newark Liberty Airport, Fort Lauderdale Hollywood International Airport, and Washington Dulles Airport.
What is the cheapest and fastest flight from Syracuse to Santo Domingo?
The cheapest flight is with JetBlue for $432, taking 7 hours 54 minutes. The fastest option is also with JetBlue for $443, taking 6 hours 9 minutes.
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