$216 Flight Deals from Syracuse to Panama City

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... and +100s more

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Stops

Up to 2 stops
$502

Airlines

American Airlines
$607
United Airlines
$502

Cabin Class

Economy
$502

Departure Airports

Syracuse Hancock International Airport
$502

Arrival Airports

Tocumen International Airport
$502

Layover Airports

Charlotte Douglas International Airport
$607
Chicago O Hare Airport
$546
George Bush Intercontinental Houston Airport
$502
Miami International Airport
$607
Newark Liberty Airport
$502
Philadelphia International Airport
$607
Reagan Washington National Airport
$607
Washington Dulles Airport
$502

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Exclusively for Priceline Members
Tired of searching? Book now!
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BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

United Airlines

09/13/25

6:00am

SYR

13h 37m

EWR

IAH

09/13/25

6:37pm

PTY

United Airlines

09/20/25

3:30pm

PTY

31h 18m

IAH

EWR

09/21/25

11:48pm

SYR

^$502

United Airlines

09/13/25

6:00am

SYR

13h 37m

EWR

IAH

09/13/25

6:37pm

PTY

United Airlines

09/20/25

9:45am

PTY

22h 59m

EWR

IAD

09/21/25

9:44am

SYR

^$502

United Airlines

09/13/25

6:00am

SYR

37h 37m

EWR

IAH

09/14/25

6:37pm

PTY

United Airlines

09/20/25

9:45am

PTY

22h 59m

EWR

IAD

09/21/25

9:44am

SYR

^$519

United Airlines

09/13/25

6:00am

SYR

33h 14m

EWR

IAH

09/14/25

2:14pm

PTY

United Airlines

09/20/25

9:45am

PTY

22h 59m

EWR

IAD

09/21/25

9:44am

SYR

^$519

United Airlines

09/13/25

6:00am

SYR

13h 37m

EWR

IAH

09/13/25

6:37pm

PTY

United Airlines

09/20/25

9:45am

PTY

23h 33m

EWR

ORD

09/21/25

10:18am

SYR

^$546

United Airlines

09/13/25

6:00am

SYR

13h 37m

EWR

IAH

09/13/25

6:37pm

PTY

United Airlines

09/20/25

9:45am

PTY

30h 1m

EWR

ORD

09/21/25

4:46pm

SYR

^$562

American Airlines

09/13/25

6:10am

SYR

9h 21m

PHL

MIA

09/13/25

2:31pm

PTY

American Airlines

09/20/25

3:31pm

PTY

24h 7m

MIA

CLT

09/21/25

4:38pm

SYR

^$607

American Airlines

09/13/25

6:10am

SYR

9h 21m

PHL

MIA

09/13/25

2:31pm

PTY

American Airlines

09/20/25

3:31pm

PTY

18h 37m

MIA

ORD

09/21/25

11:08am

SYR

^$607

American Airlines

09/13/25

6:10am

SYR

9h 21m

PHL

MIA

09/13/25

2:31pm

PTY

American Airlines

09/20/25

3:31pm

PTY

18h 29m

MIA

CLT

09/21/25

11:00am

SYR

^$607

American Airlines

09/13/25

6:10am

SYR

9h 21m

PHL

MIA

09/13/25

2:31pm

PTY

American Airlines

09/20/25

3:31pm

PTY

24h 38m

MIA

DCA

09/21/25

5:09pm

SYR

^$607

American Airlines

09/13/25

6:10am

SYR

9h 21m

PHL

MIA

09/13/25

2:31pm

PTY

American Airlines

09/20/25

3:31pm

PTY

19h

MIA

DCA

09/21/25

11:31am

SYR

^$607

American Airlines

09/13/25

4:40pm

SYR

22h 51m

ORD

MIA

09/14/25

2:31pm

PTY

American Airlines

09/20/25

3:31pm

PTY

18h 29m

MIA

CLT

09/21/25

11:00am

SYR

^$628

American Airlines

09/13/25

4:40pm

SYR

22h 51m

ORD

MIA

09/14/25

2:31pm

PTY

American Airlines

09/20/25

3:31pm

PTY

19h

MIA

DCA

09/21/25

11:31am

SYR

^$628

Top Deals on flights from Syracuse to Panama City

Syracuse, US (SYR) - Panama City, PA (PTY)

United Airlines

Sep 13

6:00am

SYR

13h 37m

EWR

IAH

Sep 13

6:37pm

PTY

as low as

^$216

Syracuse, US (SYR) - Panama City, PA (PTY)

United Airlines

Sep 13

6:00am

SYR

33h 14m

EWR

IAH

Sep 14

2:14pm

PTY

as low as

^$239

Syracuse, US (SYR) - Panama City, PA (PTY)

United Airlines

Sep 13

7:48pm

SYR

19h 2m

IAD

EWR

Sep 14

1:50pm

PTY

as low as

^$265

Syracuse, US (SYR) - Panama City, PA (PTY)

American Airlines

Sep 13

6:10am

SYR

9h 21m

PHL

MIA

Sep 13

2:31pm

PTY

as low as

^$268

Syracuse, US (SYR) - Panama City, PA (PTY)

American Airlines

Sep 13

4:40pm

SYR

22h 51m

ORD

MIA

Sep 14

2:31pm

PTY

as low as

^$295

Syracuse, US (SYR) - Panama City, PA (PTY)

American Airlines

Sep 13

8:00am

SYR

31h 31m

PHL

MIA

Sep 14

2:31pm

PTY

as low as

^$299

Syracuse, US (SYR) - Panama City, PA (PTY)

American Airlines

Sep 13

5:32am

SYR

9h 59m

DCA

MIA

Sep 13

2:31pm

PTY

as low as

^$312

Syracuse, US (SYR) - Panama City, PA (PTY)

American Airlines

Sep 13

6:47pm

SYR

20h 44m

CLT

MIA

Sep 14

2:31pm

PTY

as low as

^$318

Syracuse, US (SYR) - Panama City, PA (PTY)

American Airlines

Sep 13

12:01pm

SYR

27h 30m

DCA

MIA

Sep 14

2:31pm

PTY

as low as

^$339

Syracuse, US (SYR) - Panama City, PA (PTY)

American Airlines

Sep 13

1:43pm

SYR

25h 48m

CLT

MIA

Sep 14

2:31pm

PTY

as low as

^$339

Syracuse, US (SYR) - Panama City, PA (PTY)

United Airlines

Sep 13

6:00am

SYR

8h 50m

EWR

Sep 13

1:50pm

PTY

as low as

^$391

Syracuse, US (SYR) - Panama City, PA (PTY)

United Airlines

Sep 13

11:33am

SYR

27h 17m

EWR

Sep 14

1:50pm

PTY

as low as

^$495

Frequently Asked Questions

What is the time difference between destination and arrival?

The time difference between Syracuse, NY, and Panama City is typically 1 hour, with Panama ahead. Ensure to check the specific date as daylight savings may affect the calculation.

Is there a direct flight from Syracuse to Panama City?

There is no direct flight from Syracuse to Panama City. The cheapest available flight is with United Airlines for $502, and the fastest is with American Airlines for $607, both requiring 2 stops.

Are there convenient layover flights from Syracuse to Panama City?

Yes, there are convenient 2 stop flights from Syracuse to Panama City. United Airlines offers a flight for $502 with layovers at Newark and Houston. American Airlines has a flight for $607 with layovers at Philadelphia and Miami.

What are the most convenient layover airports for my flight?

The most convenient layover airports for your flight from Syracuse to Panama City are Newark Liberty Airport, George Bush Intercontinental Airport, Philadelphia International Airport, and Miami International Airport.

What is the cheapest and fastest flight from Syracuse to Panama City?

The cheapest flight is $502 with United Airlines, taking 13 hours 37 minutes. The fastest is $607 with American Airlines, at 9 hours 21 minutes.

What are all possible destination arrival airports?

The possible destination arrival airport is Tocumen International Airport, with layover airports being Newark Liberty Airport, George Bush Intercontinental Houston Airport, Philadelphia International Airport, and Miami International Airport.

Flights to Panama City

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Flight Deals from Syracuse to Panama City from $216

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights from Syracuse to Panama City

Frequently Asked Questions

Flights to Panama City