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Flight Deals from Santa Ana to Chicago from $130

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Bundle + Save

Top flight deals from leading airlines:

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Up to 3 stops
    $313
  • Up to 2 stops
    $308
  • Up to 1 stop
    $412

Airlines

  • Alaska Airlines
    $378
  • American Airlines
    $422
  • Delta Air Lines
    $308
  • Frontier Airlines
    $344
  • Hahn Air
    $527
  • Southwest Airlines
    $468
  • United Airlines
    $412

Cabin Class

  • Economy
    $308

Departure Airports

  • John Wayne Airport-Orange County Airport
    $308
  • Los Angeles International Airport
    $527

Arrival Airports

  • Chicago Metropolitan Area
    $308
  • Chicago Midway Airport
    $527

Layover Airports

  • Bob Hope Airport
    $308
  • Chicago Midway Airport
    $371
  • Chicago O Hare Airport
    $308
  • Denver International Airport
    $443
  • Detroit Metropolitan Airport
    $313
  • George Bush Intercontinental Houston Airport
    $501
  • Harry Reid International Airport
    $344
  • Hartsfield Jackson Atlanta International Airport
    $308
  • John Wayne Airport-Orange County Airport
    $344
  • Los Angeles International Airport
    $398
  • Minneapolis-St Paul International/Wold-Chamberlain Airport
    $351
  • Oakland International Airport
    $468
  • Ontario International Airport
    $537
  • Phoenix Sky Harbor International Airport
    $344
  • Portland International Airport
    $378
  • Salt Lake City International Airport
    $308
  • San Francisco International Airport
    $443
  • Seattle Tacoma International Airport
    $348

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

Delta Air Lines Logo
Delta Air Lines

05/11/26

SNA
8h 58m
SLC
ORD

05/11/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/16/26

CHI
5h 52m
ATL
BUR

05/16/26

SNA
$308
Delta Air Lines Logo
Delta Air Lines

05/11/26

SNA
8h 58m
SLC
ORD

05/11/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/16/26

CHI
8h 1m
DTW
SLC
BUR

05/16/26

SNA
$313
Delta Air Lines Logo
Delta Air Lines

05/10/26

SNA
8h 15m
SLC
ORD

05/10/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/16/26

CHI
5h 52m
ATL
BUR

05/16/26

SNA
$318
Bundle + Save
Book a flight & hotel together for extra savings.
On average save $240 per traveler
Delta Air Lines Logo
Delta Air Lines

05/10/26

SNA
8h 15m
SLC
ORD

05/10/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/16/26

CHI
8h 1m
DTW
SLC
BUR

05/16/26

SNA
$323
Frontier Airlines Logo
Frontier Airlines

04/30/26

SNA
10h 12m
LAS
ORD

05/01/26

CHI
Frontier Airlines Logo
Frontier Airlines

05/04/26

CHI
5h 54m
PHX
SNA

05/04/26

SNA
$344
Delta Air Lines Logo
Delta Air Lines

05/08/26

SNA
9h 57m
SEA
ORD

05/08/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/13/26

CHI
4h 5m
SLC
BUR

05/13/26

SNA
$348
Delta Air Lines Logo
Delta Air Lines

04/21/26

SNA
7h 43m
SLC
ORD

04/21/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/09/26

CHI
7h 46m
MSP
SLC
BUR

05/09/26

SNA
$351
Delta Air Lines Logo
Delta Air Lines

05/08/26

SNA
9h 57m
SEA
ORD

05/08/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/13/26

CHI
7h 45m
DTW
SLC
BUR

05/13/26

SNA
$353
Delta Air Lines Logo
Delta Air Lines

05/05/26

SNA
7h 43m
SLC
ORD

05/05/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/09/26

CHI
7h 46m
MSP
SLC
BUR

05/09/26

SNA
$353
Frontier Airlines Logo
Frontier Airlines

05/01/26

SNA
10h 12m
LAS
ORD

05/02/26

CHI
Frontier Airlines Logo
Frontier Airlines

05/04/26

CHI
5h 54m
PHX
SNA

05/04/26

SNA
$365
Delta Air Lines Logo
Delta Air Lines

05/02/26

SNA
9h 17m
ATL
MDW

05/02/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/07/26

CHI
4h 5m
SLC
BUR

05/07/26

SNA
$371
Delta Air Lines Logo
Delta Air Lines

05/02/26

SNA
9h 17m
ATL
MDW

05/02/26

CHI
Delta Air Lines Logo
Delta Air Lines

05/08/26

CHI
8h 23m
DTW
SLC
BUR

05/08/26

SNA
$376
Alaska Airlines Logo
Alaska Airlines

05/04/26

SNA
10h 50m
SEA
ORD

05/05/26

CHI
Alaska Airlines Logo
Alaska Airlines

05/05/26

CHI
6h 6m
PDX
BUR

05/05/26

SNA
$378
Bundle + Save
Book a flight & hotel together for extra savings.
On average save $240 per traveler
Alaska Airlines Logo
Alaska Airlines

04/30/26

SNA
10h 50m
SEA
ORD

05/01/26

CHI
Alaska Airlines Logo
Alaska Airlines

05/12/26

CHI
6h 6m
PDX
BUR

05/12/26

SNA
$387
Alaska Airlines Logo
Alaska Airlines

05/06/26

SNA
11h 38m
SEA
ORD

05/06/26

CHI
Alaska Airlines Logo
Alaska Airlines

05/13/26

CHI
6h 34m
SEA
LAX

05/13/26

SNA
$398
Alaska Airlines Logo
Alaska Airlines

05/05/26

SNA
13h 7m
SEA
ORD

05/05/26

CHI
Alaska Airlines Logo
Alaska Airlines

05/08/26

CHI
7h 43m
SEA
LAX

05/08/26

SNA
$398
United Airlines Logo
United Airlines

05/10/26

SNA
6h 5m
ORD

05/10/26

CHI
United Airlines Logo
United Airlines

05/16/26

CHI
2h 40m
LAX

05/16/26

SNA
$412
American Airlines Logo
American Airlines

05/10/26

SNA
6h 12m
ORD

05/10/26

CHI
American Airlines Logo
American Airlines

05/16/26

CHI
2h 39m
LAX

05/16/26

SNA
$422
United Airlines Logo
United Airlines

05/08/26

SNA
6h 5m
ORD

05/08/26

CHI
United Airlines Logo
United Airlines

05/10/26

CHI
5h 41m
SFO
BUR

05/10/26

SNA
$443
United Airlines Logo
United Airlines

05/06/26

SNA
6h 5m
ORD

05/06/26

CHI
United Airlines Logo
United Airlines

05/09/26

CHI
5h 39m
BUR

05/09/26

SNA
$443
United Airlines Logo
United Airlines

05/04/26

SNA
6h 5m
ORD

05/04/26

CHI
United Airlines Logo
United Airlines

05/09/26

CHI
4h 52m
DEN
BUR

05/09/26

SNA
$443
American Airlines Logo
American Airlines

04/29/26

SNA
6h 17m
ORD

04/29/26

CHI
American Airlines Logo
American Airlines

05/02/26

CHI
4h 1m
PHX
BUR

05/02/26

SNA
$451
United Airlines Logo
United Airlines

04/22/26

SNA
6h 5m
ORD

04/22/26

CHI
United Airlines Logo
United Airlines

05/05/26

CHI
6h 2m
DEN
BUR

05/05/26

SNA
$466
Bundle + Save
Book a flight & hotel together for extra savings.
On average save $240 per traveler
United Airlines Logo
United Airlines

05/02/26

SNA
6h 5m
ORD

05/02/26

CHI
United Airlines Logo
United Airlines

05/06/26

CHI
5h 16m
SFO
BUR

05/06/26

SNA
$466
Southwest Airlines Logo
Southwest Airlines

04/26/26

SNA
8h 55m
OAK
MDW

04/27/26

CHI
Southwest Airlines Logo
Southwest Airlines

05/04/26

CHI
4h 10m
DEN
BUR

05/04/26

SNA
$468
Southwest Airlines Logo
Southwest Airlines

04/26/26

SNA
7h 50m
PHX
MDW

04/27/26

CHI
Southwest Airlines Logo
Southwest Airlines

05/04/26

CHI
2h 25m
LAX

05/04/26

SNA
$472
United Airlines Logo
United Airlines

04/21/26

SNA
9h 16m
IAH
ORD

04/22/26

CHI
United Airlines Logo
United Airlines

05/02/26

CHI
4h 52m
DEN
BUR

05/02/26

SNA
$501
Southwest Airlines Logo
Southwest Airlines

04/26/26

SNA
6h 55m
OAK

04/27/26

MDW
Southwest Airlines Logo
Southwest Airlines

05/04/26

MDW
4h 25m
Direct

05/04/26

LAX
$527
Hahn Air Logo
Hahn Air

04/26/26

SNA
8h 55m
OAK
MDW

04/27/26

CHI
Hahn Air Logo
Hahn Air

05/04/26

CHI
2h 25m
LAX

05/04/26

SNA
$527
Alaska Airlines Logo
Alaska Airlines

05/11/26

SNA
6h 12m
ORD

05/11/26

CHI
Alaska Airlines Logo
Alaska Airlines

05/11/26

CHI
6h 7m
SEA
ONT

05/11/26

SNA
$537

Top Deals on flights from Santa Ana to Chicago

Santa Ana, US (SNA) - Chicago, US (CHI)

Frontier Airlines Logo
Frontier Airlines

May 9

SNA
10h 38m
DEN
ORD

May 9

CHI

as low as

$130

Santa Ana, US (SNA) - Chicago, US (CHI)

American Airlines Logo
American Airlines

May 5

SNA
4h 17m
Direct

May 5

ORD

as low as

$130

Santa Ana, US (SNA) - Chicago, US (CHI)

American Airlines Logo
American Airlines

May 5

SNA
9h 6m
DFW
ORD

May 5

CHI

as low as

$140

Santa Ana, US (SNA) - Chicago, US (CHI)

Alaska Airlines Logo
Alaska Airlines

May 20

SNA
10h 58m
SEA
ORD

May 20

CHI

as low as

$154

Santa Ana, US (SNA) - Chicago, US (CHI)

Alaska Airlines Logo
Alaska Airlines

May 12

SNA
10h 58m
PDX
ORD

May 13

CHI

as low as

$174

Santa Ana, US (SNA) - Chicago, US (CHI)

Frontier Airlines Logo
Frontier Airlines

Apr 30

SNA
10h 12m
LAS
ORD

May 1

CHI

as low as

$184

Santa Ana, US (SNA) - Chicago, US (CHI)

 Logo

Jun 6

SNA
15h 21m
LAS
IAH

Jun 7

ORD

as low as

$191

Santa Ana, US (SNA) - Chicago, US (CHI)

Southwest Airlines Logo
Southwest Airlines

Apr 28

SNA
5h 40m
PHX

Apr 28

ORD

as low as

$232

Santa Ana, US (SNA) - Chicago, US (CHI)

Hawaiian Airlines Logo
Hawaiian Airlines

Apr 21

SNA
11h 52m
SEA
ORD

Apr 21

CHI

as low as

$234

Santa Ana, US (SNA) - Chicago, US (CHI)

United Airlines Logo
United Airlines

May 11

SNA
6h 5m
ORD

May 11

CHI

as low as

$248

Santa Ana, US (SNA) - Chicago, US (CHI)

Delta Air Lines Logo
Delta Air Lines

May 14

SNA
9h 57m
SEA
ORD

May 14

CHI

as low as

$261

Santa Ana, US (SNA) - Chicago, US (CHI)

Delta Air Lines Logo
Delta Air Lines

May 10

SNA
8h 15m
SLC
ORD

May 10

CHI

as low as

$292

Good to Know

Essential information to help you plan your flight from Santa Ana to Chicago

Cheapest Flight

$130

The lowest price we found in the last two weeks, departing May 9 and returning May 9

Airline F92 stops ‧ 10h 38m ‧ economy

Fastest Flights

$130

The fastest flight that we found in the last two weeks, departing May 5 and returning May 5

Airline AA4h 17m ‧ economy

Cheapest Flight Round-trip

$308

Cheapest price found in the last 14 days, departing May 11 and returning May 16

Airline DL2 stops ‧ 8h 58m ‧ economy

Cheapest Flight One-way

$130

Cheapest price found in the last 14 days, departing May 9

Airline F92 stops ‧ 10h 38m ‧ economy

Cheapest Layover airport

$232

The cheapest layover airport to Chicago is currently $232

Airline WN1 stop ‧ 5h 40m ‧ economy

Best Arrival airport

$130

The best arrival airport to Chicago is currently $130

Airline AA4h 17m ‧ economy

Best Departure airport

$130

The best departure airport to Chicago is currently $130

Airline AA4h 17m ‧ economy

Cheapest Airline

$130

The cheapest airline to Chicago is currently $130

Airline AA4h 17m ‧ economy

Flights to Chicago