background

Flight Deals from Santo Domingo to San Jose from $288

Bundle + Save

Bundle + Save

Top flight deals from leading airlines:

UA LogoB6 LogoAM LogoCM LogoQR LogoSQ LogoNH Logo

... and +100s more

Incredible Deals

Save up to 50% on select flights with Priceline

Bundle & Save

Save an average of $240 per person when bundling your flight and hotel together with Priceline

Best Price Guarantee

If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference

Help 24/7

We’re always here for you - reach us 24 hours a day, 7 days a week

Stops

  • Up to 1 stop
    $534
  • Up to 2 stops
    $740

Airlines

  • American Airlines
    $740
  • COPA Airlines
    $588
  • JetBlue
    $534
  • United Airlines
    $674

Cabin Class

  • Economy
    $534

Departure Airports

  • Las Américas International Airport
    $534

Arrival Airports

  • Norman Y. Mineta San Jose International Airport
    $740
  • San Francisco International Airport
    $534

Layover Airports

  • Dallas Fort Worth International Airport
    $740
  • Fort Lauderdale Hollywood International Airport
    $534
  • Miami International Airport
    $740
  • New York John F Kennedy Airport
    $534
  • Newark Liberty Airport
    $674
  • Phoenix Sky Harbor International Airport
    $740
  • Tocumen International Airport
    $588

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

Phone Banner
Priceline Phone Deals
Book with an agent for great rates!
BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
JetBlue Logo
JetBlue

09/16/25

SDQ
15h 12m
JFK

09/17/25

SFO
JetBlue Logo
JetBlue

09/23/25

SFO
11h 4m
FLL

09/24/25

SDQ
$534
JetBlue Logo
JetBlue

09/16/25

SDQ
12h 56m
JFK

09/17/25

SFO
JetBlue Logo
JetBlue

09/23/25

SFO
11h 4m
FLL

09/24/25

SDQ
$534
JetBlue Logo
JetBlue

09/16/25

SDQ
15h 12m
JFK

09/17/25

SFO
JetBlue Logo
JetBlue

09/23/25

SFO
23h 49m
FLL

09/24/25

SDQ
$546
JetBlue Logo
JetBlue

09/16/25

SDQ
12h 56m
JFK

09/17/25

SFO
JetBlue Logo
JetBlue

09/23/25

SFO
23h 49m
FLL

09/24/25

SDQ
$546
JetBlue Logo
JetBlue

09/16/25

SDQ
15h 12m
JFK

09/17/25

SFO
JetBlue Logo
JetBlue

09/23/25

SFO
14h 25m
JFK

09/24/25

SDQ
$553
JetBlue Logo
JetBlue

09/16/25

SDQ
12h 56m
JFK

09/17/25

SFO
JetBlue Logo
JetBlue

09/23/25

SFO
15h 20m
JFK

09/24/25

SDQ
$553
JetBlue Logo
JetBlue

09/16/25

SDQ
12h 56m
JFK

09/17/25

SFO
JetBlue Logo
JetBlue

09/23/25

SFO
13h 16m
JFK

09/23/25

SDQ
$553
JetBlue Logo
JetBlue

09/16/25

SDQ
11h 36m
FLL

09/16/25

SFO
JetBlue Logo
JetBlue

09/23/25

SFO
11h 4m
FLL

09/24/25

SDQ
$560
JetBlue Logo
JetBlue

09/16/25

SDQ
18h 19m
JFK

09/17/25

SFO
JetBlue Logo
JetBlue

09/23/25

SFO
11h 4m
FLL

09/24/25

SDQ
$567
COPA Airlines Logo
COPA Airlines

09/16/25

SDQ
14h 29m
PTY

09/16/25

SFO
COPA Airlines Logo
COPA Airlines

09/23/25

SFO
17h 56m
PTY

09/23/25

SDQ
$588
COPA Airlines Logo
COPA Airlines

09/16/25

SDQ
12h 16m
PTY

09/16/25

SFO
COPA Airlines Logo
COPA Airlines

09/23/25

SFO
17h 56m
PTY

09/23/25

SDQ
$588
COPA Airlines Logo
COPA Airlines

09/16/25

SDQ
17h 26m
PTY

09/16/25

SFO
COPA Airlines Logo
COPA Airlines

09/23/25

SFO
11h 47m
PTY

09/23/25

SDQ
$588
COPA Airlines Logo
COPA Airlines

09/16/25

SDQ
21h
PTY

09/16/25

SFO
COPA Airlines Logo
COPA Airlines

09/23/25

SFO
11h 47m
PTY

09/23/25

SDQ
$588
COPA Airlines Logo
COPA Airlines

09/16/25

SDQ
17h 26m
PTY

09/16/25

SFO
COPA Airlines Logo
COPA Airlines

09/23/25

SFO
17h 56m
PTY

09/23/25

SDQ
$588
COPA Airlines Logo
COPA Airlines

09/16/25

SDQ
14h 29m
PTY

09/16/25

SFO
COPA Airlines Logo
COPA Airlines

09/23/25

SFO
11h 47m
PTY

09/23/25

SDQ
$588
COPA Airlines Logo
COPA Airlines

09/16/25

SDQ
21h
PTY

09/16/25

SFO
COPA Airlines Logo
COPA Airlines

09/23/25

SFO
17h 56m
PTY

09/23/25

SDQ
$588
United Airlines Logo
United Airlines

09/16/25

SDQ
14h 56m
EWR

09/16/25

SFO
United Airlines Logo
United Airlines

09/23/25

SFO
11h
EWR

09/24/25

SDQ
$674
United Airlines Logo
United Airlines

09/16/25

SDQ
14h 56m
EWR

09/16/25

SFO
United Airlines Logo
United Airlines

09/23/25

SFO
15h 45m
EWR

09/24/25

SDQ
$674
United Airlines Logo
United Airlines

09/16/25

SDQ
14h 56m
EWR

09/16/25

SFO
United Airlines Logo
United Airlines

09/23/25

SFO
11h 40m
EWR

09/24/25

SDQ
$674
United Airlines Logo
United Airlines

09/16/25

SDQ
14h 56m
EWR

09/16/25

SFO
United Airlines Logo
United Airlines

09/23/25

SFO
11h 45m
EWR

09/24/25

SDQ
$674
United Airlines Logo
United Airlines

09/16/25

SDQ
11h 56m
EWR

09/16/25

SFO
United Airlines Logo
United Airlines

09/23/25

SFO
13h 55m
EWR

09/24/25

SDQ
$674
United Airlines Logo
United Airlines

09/16/25

SDQ
13h 39m
EWR

09/16/25

SFO
United Airlines Logo
United Airlines

09/23/25

SFO
12h 25m
EWR

09/24/25

SDQ
$674
United Airlines Logo
United Airlines

09/16/25

SDQ
13h 21m
EWR

09/16/25

SFO
United Airlines Logo
United Airlines

09/23/25

SFO
12h 25m
EWR

09/24/25

SDQ
$674
American Airlines Logo
American Airlines

09/16/25

SDQ
17h 8m
MIA
DFW

09/16/25

SJC
American Airlines Logo
American Airlines

09/23/25

SJC
19h 30m
PHX
MIA

09/24/25

SDQ
$740
American Airlines Logo
American Airlines

09/16/25

SDQ
17h 8m
MIA
DFW

09/16/25

SJC
American Airlines Logo
American Airlines

09/23/25

SJC
11h 30m
PHX
MIA

09/23/25

SDQ
$740
American Airlines Logo
American Airlines

09/16/25

SDQ
12h 41m
MIA
DFW

09/16/25

SJC
American Airlines Logo
American Airlines

09/23/25

SJC
21h 50m
PHX
MIA

09/24/25

SDQ
$740
American Airlines Logo
American Airlines

09/16/25

SDQ
23h 19m
MIA
DFW

09/17/25

SJC
American Airlines Logo
American Airlines

09/23/25

SJC
11h 30m
PHX
MIA

09/23/25

SDQ
$740
American Airlines Logo
American Airlines

09/16/25

SDQ
14h 35m
MIA
PHX

09/16/25

SJC
American Airlines Logo
American Airlines

09/23/25

SJC
11h 30m
PHX
MIA

09/23/25

SDQ
$740
American Airlines Logo
American Airlines

09/16/25

SDQ
14h 35m
MIA
PHX

09/16/25

SJC
American Airlines Logo
American Airlines

09/23/25

SJC
19h 30m
PHX
MIA

09/24/25

SDQ
$740
American Airlines Logo
American Airlines

09/16/25

SDQ
14h 35m
MIA
PHX

09/16/25

SJC
American Airlines Logo
American Airlines

09/23/25

SJC
21h 50m
PHX
MIA

09/24/25

SDQ
$740

Top Deals on flights from Santo Domingo to San Jose

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

JetBlue Logo
JetBlue

Sep 16

SDQ
12h 56m
JFK

Sep 17

SFO

as low as

$288

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

JetBlue Logo
JetBlue

Sep 16

SDQ
15h 12m
JFK

Sep 17

SFO

as low as

$288

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

COPA Airlines Logo
COPA Airlines

Sep 16

SDQ
12h 16m
PTY

Sep 16

SFO

as low as

$303

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

COPA Airlines Logo
COPA Airlines

Sep 16

SDQ
14h 29m
PTY

Sep 16

SFO

as low as

$303

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

JetBlue Logo
JetBlue

Sep 16

SDQ
11h 36m
FLL

Sep 16

SFO

as low as

$316

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

COPA Airlines Logo
COPA Airlines

Sep 16

SDQ
32h 8m
PTY

Sep 17

SFO

as low as

$327

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

JetBlue Logo
JetBlue

Sep 16

SDQ
19h 49m
JFK

Sep 17

SFO

as low as

$334

Santo Domingo, DO (SDQ) - San Jose, US (SJC)

American Airlines Logo
American Airlines

Sep 16

SDQ
12h 41m
MIA
DFW

Sep 16

SJC

as low as

$396

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

United Airlines Logo
United Airlines

Sep 16

SDQ
14h 56m
EWR

Sep 16

SFO

as low as

$418

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

United Airlines Logo
United Airlines

Sep 16

SDQ
11h 56m
EWR

Sep 16

SFO

as low as

$418

Santo Domingo, DO (SDQ) - San Francisco, US (SFO)

United Airlines Logo
United Airlines

Sep 16

SDQ
22h 2m
EWR

Sep 17

SFO

as low as

$418

Santo Domingo, DO (SDQ) - San Jose, US (SJC)

American Airlines Logo
American Airlines

Sep 16

SDQ
22h 44m
MIA
PHX

Sep 17

SJC

as low as

$420

Frequently Asked Questions

What is the cheapest and fastest flight from Santo Domingo to San Jose?
The cheapest flight is with JetBlue at $534, taking 12 hours 56 minutes. The fastest flight is with American Airlines at $769, taking 11 hours 19 minutes.
What are all possible destination arrival airports?
Possible destination arrival airports include San Francisco International Airport and Norman Y. Mineta San Jose International Airport.
What is the time difference between destination and arrival?
The time difference between Santo Domingo and San Jose can vary depending on the date, but it is generally one hour earlier in San Jose.
Is there a direct flight from Santo Domingo to San Jose?
There is no direct flight from Santo Domingo to San Jose.
Are there convenient layover flights from Santo Domingo to San Jose?
Yes, there are convenient layover flights. Airlines with options include JetBlue at $534, COPA Airlines at $588, United Airlines at $674, American Airlines at $769, and Aeromexico at $821. For 2 stops, American Airlines offers a flight at $740.
What are the most convenient layover airports for the flight?
For your flight from Santo Domingo to San Jose, the most convenient layover airports are New York John F Kennedy, Miami International, Tocumen International, Newark Liberty, and Licenciado Benito Juarez.
Priceline Phone Deals

Book with an agent for great rates!
Call now!

1 (888) 775-6158