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Flight Deals from Santo Domingo to Puerto Rico from $254

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Top Deals on flights from Santo Domingo to San Juan

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

JetBlue Logo
JetBlue

Apr 10

SDQ
1h
Direct

Apr 10

SJU
JetBlue Logo
JetBlue

Apr 13

SJU
1h 5m
Direct

Apr 13

SDQ

as low as

$254

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

JetBlue Logo
JetBlue

Apr 17

SDQ
57m
Direct

Apr 17

SJU
JetBlue Logo
JetBlue

Apr 20

SJU
1h 1m
Direct

Apr 20

SDQ

as low as

$254

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

Hahn Air Logo
Hahn Air

Apr 22

SDQ
1h 9m
Direct

Apr 22

SJU
Hahn Air Logo
Hahn Air

Apr 22

SJU
1h 9m
Direct

Apr 22

SDQ

as low as

$306

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

Flexflight Logo
Flexflight

Apr 22

SDQ
1h 9m
Direct

Apr 22

SJU
Flexflight Logo
Flexflight

Apr 22

SJU
1h 9m
Direct

Apr 22

SDQ

as low as

$312

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

Flexflight Logo
Flexflight

Apr 25

SDQ
1h 9m
Direct

Apr 25

SJU
Flexflight Logo
Flexflight

Apr 27

SJU
1h 9m
Direct

Apr 27

SDQ

as low as

$321

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

Hahn Air Logo
Hahn Air

Apr 25

SDQ
1h 9m
Direct

Apr 25

SJU
Hahn Air Logo
Hahn Air

Apr 27

SJU
1h 9m
Direct

Apr 27

SDQ

as low as

$339

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

COPA Airlines Logo
COPA Airlines

Apr 24

SDQ
9h 46m
PTY

Apr 24

SJU
COPA Airlines Logo
COPA Airlines

Apr 27

SJU
20h 53m
PTY

Apr 28

SDQ

as low as

$420

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

COPA Airlines Logo
COPA Airlines

Apr 2

SDQ
10h 7m
PTY

Apr 2

SJU
COPA Airlines Logo
COPA Airlines

Apr 9

SJU
28h 35m
PTY

Apr 10

SDQ

as low as

$431

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

American Airlines Logo
American Airlines

Apr 25

SDQ
11h 12m
MIA

Apr 25

SJU
American Airlines Logo
American Airlines

Apr 27

SJU
11h 10m
MIA

Apr 27

SDQ

as low as

$776

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

American Airlines Logo
American Airlines

Apr 24

SDQ
16h 58m
MIA

Apr 25

SJU
American Airlines Logo
American Airlines

Apr 27

SJU
17h 7m
MIA

Apr 27

SDQ

as low as

$776

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

interCaribbean Airways Logo
interCaribbean Airways

Apr 22

SDQ
19h 35m
EIS

Apr 23

SJU
interCaribbean Airways Logo
interCaribbean Airways

Apr 23

SJU
23h 40m
EIS

Apr 24

SDQ

as low as

$927

Santo Domingo, DO (SDQ) - San Juan, PR (SJU)

interCaribbean Airways Logo
interCaribbean Airways

Apr 15

SDQ
22h 10m
EIS

Apr 16

SJU
interCaribbean Airways Logo
interCaribbean Airways

Apr 20

SJU
19h 35m
EIS

Apr 21

SDQ

as low as

$933

Top Deals on flights from Santo Domingo to Aguadilla

Santo Domingo, DO (SDQ) - Aguadilla, PR (BQN)

United Airlines Logo
United Airlines

Apr 19

SDQ
17h 9m
EWR

Apr 19

BQN
United Airlines Logo
United Airlines

May 3

BQN
11h 40m
EWR

May 3

SDQ

as low as

$1003

Santo Domingo, DO (SDQ) - Aguadilla, PR (BQN)

United Airlines Logo
United Airlines

Apr 19

SDQ
17h 9m
EWR

Apr 19

BQN
United Airlines Logo
United Airlines

May 3

BQN
13h 55m
EWR

May 3

SDQ

as low as

$1003

Santo Domingo, DO (SDQ) - Aguadilla, PR (BQN)

United Airlines Logo
United Airlines

Apr 19

SDQ
17h 9m
EWR

Apr 19

BQN
United Airlines Logo
United Airlines

May 3

BQN
22h 31m
EWR

May 3

SDQ

as low as

$1049

Santo Domingo, DO (SDQ) - Aguadilla, PR (BQN)

United Airlines Logo
United Airlines

Apr 19

SDQ
9h 59m
EWR

Apr 19

BQN
United Airlines Logo
United Airlines

May 3

BQN
13h 55m
EWR

May 3

SDQ

as low as

$1112

Santo Domingo, DO (SDQ) - Aguadilla, PR (BQN)

United Airlines Logo
United Airlines

Apr 19

SDQ
9h 59m
EWR

Apr 19

BQN
United Airlines Logo
United Airlines

May 3

BQN
11h 40m
EWR

May 3

SDQ

as low as

$1112

Santo Domingo, DO (SDQ) - Aguadilla, PR (BQN)

United Airlines Logo
United Airlines

Apr 19

SDQ
9h 59m
EWR

Apr 19

BQN
United Airlines Logo
United Airlines

May 3

BQN
22h 31m
EWR

May 3

SDQ

as low as

$1159

Santo Domingo, DO (SDQ) - Aguadilla, PR (BQN)

United Airlines Logo
United Airlines

Apr 19

SDQ
9h 59m
EWR

Apr 19

BQN
United Airlines Logo
United Airlines

May 3

BQN
13h 3m
EWR
MIA

May 3

SDQ

as low as

$9710

Santo Domingo, DO (SDQ) - Aguadilla, PR (BQN)

United Airlines Logo
United Airlines

Apr 19

SDQ
17h 9m
EWR

Apr 19

BQN
United Airlines Logo
United Airlines

May 3

BQN
13h 3m
EWR
MIA

May 3

SDQ

as low as

$9710

Top Deals on flights from Santo Domingo to Ponce

Santo Domingo, DO (SDQ) - Ponce, PR (PSE)

AVIANCA Logo
AVIANCA

Apr 9

SDQ
24h 14m
BOG
MCO

Apr 10

PSE
JetBlue Logo
JetBlue

Apr 23

PSE
27h 11m
MCO
BOG

Apr 24

SDQ

as low as

$1142

Santo Domingo, DO (SDQ) - Ponce, PR (PSE)

AVIANCA Logo
AVIANCA

Apr 9

SDQ
30h 19m
BOG
MCO

Apr 10

PSE
JetBlue Logo
JetBlue

Apr 23

PSE
27h 11m
MCO
BOG

Apr 24

SDQ

as low as

$1142

Top Deals on flights from Santo Domingo to Culebra

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
6h 35m
SJU

Apr 27

CPX
JetBlue Logo
JetBlue

May 4

CPX
21h 56m
SJU

May 5

SDQ

as low as

$615

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
9h 58m
SJU

Apr 28

CPX
JetBlue Logo
JetBlue

May 4

CPX
21h 56m
SJU

May 5

SDQ

as low as

$615

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
5h 5m
SJU

Apr 27

CPX
JetBlue Logo
JetBlue

May 4

CPX
21h 56m
SJU

May 5

SDQ

as low as

$615

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
12h 3m
SJU

Apr 28

CPX
JetBlue Logo
JetBlue

May 4

CPX
21h 56m
SJU

May 5

SDQ

as low as

$615

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
5h 5m
SJU

Apr 27

CPX
JetBlue Logo
JetBlue

May 4

CPX
21h 56m
SJU

May 5

SDQ

as low as

$633

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
9h 58m
SJU

Apr 28

CPX
JetBlue Logo
JetBlue

May 4

CPX
21h 56m
SJU

May 5

SDQ

as low as

$633

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
12h 3m
SJU

Apr 28

CPX
JetBlue Logo
JetBlue

May 4

CPX
21h 56m
SJU

May 5

SDQ

as low as

$633

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
6h 35m
SJU

Apr 27

CPX
JetBlue Logo
JetBlue

May 4

CPX
21h 56m
SJU

May 5

SDQ

as low as

$633

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
9h 58m
SJU

Apr 28

CPX
Cape Air Logo
Cape Air

May 4

CPX
5h 53m
SJU

May 4

SDQ

as low as

$667

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

JetBlue Logo
JetBlue

Apr 27

SDQ
5h 5m
SJU

Apr 27

CPX
Cape Air Logo
Cape Air

May 4

CPX
4h 23m
SJU

May 4

SDQ

as low as

$667

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

interCaribbean Airways Logo
interCaribbean Airways

Apr 27

SDQ
26h 8m
EIS
SJU

Apr 28

CPX
Cape Air Logo
Cape Air

May 4

CPX
24h
SJU
EIS

May 5

SDQ

as low as

$1251

Santo Domingo, DO (SDQ) - Culebra, PR (CPX)

interCaribbean Airways Logo
interCaribbean Airways

Apr 27

SDQ
26h 8m
EIS
SJU

Apr 28

CPX
Cape Air Logo
Cape Air

May 4

CPX
22h 2m
SJU
EIS

May 5

SDQ

as low as

$1251

Top Deals on flights from Santo Domingo to Mayagueez

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
6h 33m
SJU

Apr 27

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
15h 50m
SJU

May 5

SDQ

as low as

$497

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
9h 5m
SJU

Apr 27

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
4h 20m
SJU

May 4

SDQ

as low as

$573

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
11h 35m
SJU

Apr 28

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
4h 20m
SJU

May 4

SDQ

as low as

$573

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
14h 37m
SJU

Apr 28

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
4h 20m
SJU

May 4

SDQ

as low as

$573

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
6h 33m
SJU

Apr 27

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
10h 49m
SJU

May 4

SDQ

as low as

$573

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
6h 33m
SJU

Apr 27

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
7h 37m
SJU

May 4

SDQ

as low as

$573

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
9h 5m
SJU

Apr 27

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
7h 37m
SJU

May 4

SDQ

as low as

$573

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
6h 33m
SJU

Apr 27

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
4h 20m
SJU

May 4

SDQ

as low as

$573

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
11h 35m
SJU

Apr 28

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
7h 37m
SJU

May 4

SDQ

as low as

$573

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
11h 35m
SJU

Apr 28

MAZ
JetBlue Logo
JetBlue

May 4

MAZ
4h 20m
SJU

May 4

SDQ

as low as

$601

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Apr 27

SDQ
9h 5m
SJU

Apr 27

MAZ
JetBlue Logo
JetBlue

May 4

MAZ
4h 20m
SJU

May 4

SDQ

as low as

$601

Santo Domingo, DO (SDQ) - Mayagueez, PR (MAZ)

interCaribbean Airways Logo
interCaribbean Airways

Apr 27

SDQ
19h 37m
EIS
SJU

Apr 28

MAZ
Cape Air Logo
Cape Air

May 4

MAZ
23h 46m
SJU
EIS

May 5

SDQ

as low as

$1140

Good to Know

Essential information to help you plan your flight from Santo Domingo to Puerto Rico

Cheapest Flight

$254

The lowest price we found in the last two weeks, departing Apr 10 and returning Apr 13

Airline B61h ‧ economy

Fastest Flights

$254

The fastest flight that we found in the last two weeks, departing Apr 17 and returning Apr 20

Airline B657m ‧ economy

Cheapest Flight Round-trip

$254

Cheapest price found in the last 14 days, departing Apr 10 and returning Apr 13

Airline B61h ‧ economy

Cheapest Layover airport

$927

The cheapest layover airport to San Juan is currently $927

Airline JY1 stop ‧ 19h 35m ‧ economy

Best Arrival airport

$254

The best arrival airport to San Juan is currently $254

Airline B657m ‧ economy

Best Departure airport

$254

The best departure airport to San Juan is currently $254

Airline B657m ‧ economy

Cheapest Airline

$254

The cheapest airline to San Juan is currently $254

Airline B657m ‧ economy

Frequently Asked Questions

Which cities in Puerto Rico can I fly to from Santo Domingo?

From Santo Domingo you can fly directly to San Juan, the main gateway in Puerto Rico, with additional options to other cities like Ponce and Aguadilla via connecting flights. San Juan's Luis Muñoz Marín Airport is the primary hub for international travelers, ideal for exploring the island's beaches, historic sites, and resorts.

How long is the flight from Santo Domingo to Puerto Rico?

Flights from Santo Domingo to Puerto Rico are usually non-stop and take about 1 hour 15 minutes to 1 hour 30 minutes. One-stop flights are uncommon and generally take around 2 to 4 hours including layovers.

Are there direct flights from Santo Domingo to Puerto Rico?

Yes, there are direct flights from Santo Domingo to Puerto Rico. Airlines like JetBlue and Puerto Rican Airlines operate non-stop flights between Santo Domingo's Las Américas Airport and San Juan's Luis Muñoz Marín Airport, with flight times around one hour.

Which airlines fly from Santo Domingo to Puerto Rico?

Santo Domingo to Puerto Rico mainly by JetBlue and American Airlines with direct flights; some options via regional carriers.

When is the cheapest time to fly from Santo Domingo to Puerto Rico?

Flights from Santo Domingo to Puerto Rico are typically more affordable in the late fall and early winter months, avoiding peak summer and holiday periods. Booking midweek flights and choosing morning or late evening departures can also help save money.

How far in advance should I book flights from Santo Domingo to Puerto Rico?

For Santo Domingo to Puerto Rico, booking 2 to 4 weeks ahead generally secures good prices and availability, especially outside peak seasons.

What are the most popular cities to visit in Puerto Rico?

In Puerto Rico, San Juan is the main gateway with its historic Old San Juan and vibrant culture. Other popular destinations include Ponce for its art and architecture, Rincón for surfing and beaches, and El Yunque National Forest for nature lovers.

Do I need a visa to travel from Santo Domingo to Puerto Rico?

U.S. citizens traveling from Santo Domingo to Puerto Rico do not need a visa for short visits, as Puerto Rico is a U.S. territory. No electronic travel authorization is required for U.S. citizens, but always verify current entry rules before traveling as policies can change.

Which airports in Puerto Rico are best to fly into from Santo Domingo?

Puerto Rico's main international airport is Luis Muñoz Marín Airport in San Juan, which offers the most flight options from Santo Domingo and is ideal for accessing resorts and urban attractions. Rafael Hernández Airport in Aguadilla is smaller and better for regional travel to the northwest coast.

What is the baggage allowance on flights from Santo Domingo to Puerto Rico?

Baggage allowances from Santo Domingo to Puerto Rico vary by airline and fare. Basic economy fares often do not include checked bags, while standard economy usually includes one checked bag and a carry-on. Premium cabins include more baggage and additional amenities.

What cabin and seat options are typical from Santo Domingo to Puerto Rico?

Flights from Santo Domingo to Puerto Rico typically offer Economy and Business class with lie-flat seats on some carriers, while Premium Economy and First class are uncommon.

Are overnight flights available from Santo Domingo to Puerto Rico?

Yes. Flights from Santo Domingo to Puerto Rico often depart in the evening and arrive early the next morning, offering a quick overnight option for travelers wanting to maximize their time.

When is the best time of year to visit Puerto Rico?

The best times to visit Puerto Rico are from April to June and September to November, when the weather is warm and pleasant, and tourist crowds are lighter compared to the busy summer months.