background

Flight Deals from Santo Domingo to Detroit from $222

Bundle + Save

Bundle + Save

Top flight deals from leading airlines:

DL LogoUA LogoB6 LogoQR LogoSQ LogoNH LogoEK Logo

... and +100s more

Incredible Deals

Save up to 50% on select flights with Priceline

Bundle & Save

Save an average of $240 per person when bundling your flight and hotel together with Priceline

Best Price Guarantee

If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference

Help 24/7

We’re always here for you - reach us 24 hours a day, 7 days a week

Stops

  • Up to 1 stop
    $398
  • Up to 2 stops
    $700

Airlines

  • American Airlines
    $620
  • Delta Air Lines
    $601
  • Frontier Airlines
    $462
  • JetBlue
    $536
  • Spirit Airlines
    $398
  • United Airlines
    $621

Cabin Class

  • Economy
    $398

Departure Airports

  • Las Américas International Airport
    $398

Arrival Airports

  • Detroit Metropolitan Airport
    $398

Layover Airports

  • Charlotte Douglas International Airport
    $700
  • Cincinnati Northern Kentucky International Airport
    $1719
  • Fort Lauderdale Hollywood International Airport
    $398
  • Hartsfield Jackson Atlanta International Airport
    $462
  • Miami International Airport
    $620
  • New York John F Kennedy Airport
    $536
  • Newark Liberty Airport
    $621
  • Orlando International Airport
    $458
  • Reagan Washington National Airport
    $728

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

Phone Banner
Priceline Phone Deals
Book with an agent for great rates!
BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
Spirit Airlines Logo
Spirit Airlines

07/23/25

SDQ
13h 33m
FLL

07/24/25

DTW
Spirit Airlines Logo
Spirit Airlines

07/30/25

DTW
16h 24m
FLL

07/31/25

SDQ
$398
Spirit Airlines Logo
Spirit Airlines

07/03/25

SDQ
12h 56m
MCO

07/03/25

DTW
Spirit Airlines Logo
Spirit Airlines

08/21/25

DTW
9h 32m
FLL

08/21/25

SDQ
$458
Frontier Airlines Logo
Frontier Airlines

06/30/25

SDQ
9h 34m
ATL

06/30/25

DTW
Frontier Airlines Logo
Frontier Airlines

07/12/25

DTW
21h 39m
MCO

07/13/25

SDQ
$462
JetBlue Logo
JetBlue

07/23/25

SDQ
14h 54m
JFK

07/23/25

DTW
JetBlue Logo
JetBlue

07/30/25

DTW
15h 40m
JFK

07/30/25

SDQ
$536
Spirit Airlines Logo
Spirit Airlines

06/28/25

SDQ
17h 25m
FLL

06/29/25

DTW
Spirit Airlines Logo
Spirit Airlines

07/20/25

DTW
16h 24m
FLL

07/21/25

SDQ
$542
Frontier Airlines Logo
Frontier Airlines

07/23/25

SDQ
9h 37m
ATL

07/23/25

DTW
Frontier Airlines Logo
Frontier Airlines

07/30/25

DTW
21h 28m
MCO

07/31/25

SDQ
$585
Delta Air Lines Logo
Delta Air Lines

07/03/25

SDQ
9h 6m
JFK

07/03/25

DTW
Delta Air Lines Logo
Delta Air Lines

08/21/25

DTW
15h 37m
ATL

08/22/25

SDQ
$601
JetBlue Logo
JetBlue

07/03/25

SDQ
26h 55m
JFK

07/04/25

DTW
JetBlue Logo
JetBlue

08/21/25

DTW
15h 40m
JFK

08/21/25

SDQ
$604
American Airlines Logo
American Airlines

07/23/25

SDQ
27h 55m
MIA

07/24/25

DTW
American Airlines Logo
American Airlines

07/30/25

DTW
12h 5m
MIA

07/30/25

SDQ
$620
United Airlines Logo
United Airlines

08/12/25

SDQ
17h 27m
EWR

08/12/25

DTW
United Airlines Logo
United Airlines

09/10/25

DTW
12h 25m
EWR

09/11/25

SDQ
$621
United Airlines Logo
United Airlines

07/03/25

SDQ
17h 28m
EWR

07/04/25

DTW
United Airlines Logo
United Airlines

08/21/25

DTW
7h
EWR

08/21/25

SDQ
$633
American Airlines Logo
American Airlines

07/03/25

SDQ
15h 54m
MIA
CLT

07/04/25

DTW
American Airlines Logo
American Airlines

08/21/25

DTW
12h 24m
CLT
MIA

08/21/25

SDQ
$700
American Airlines Logo
American Airlines

07/03/25

SDQ
18h 40m
MIA
CLT

07/04/25

DTW
American Airlines Logo
American Airlines

08/21/25

DTW
9h 20m
MIA

08/21/25

SDQ
$700
American Airlines Logo
American Airlines

07/03/25

SDQ
27h 45m
MIA

07/04/25

DTW
American Airlines Logo
American Airlines

08/21/25

DTW
14h 25m
MIA

08/21/25

SDQ
$711
American Airlines Logo
American Airlines

08/12/25

SDQ
16h 30m
MIA

08/12/25

DTW
American Airlines Logo
American Airlines

09/10/25

DTW
7h 29m
MIA

09/10/25

SDQ
$724
American Airlines Logo
American Airlines

08/12/25

SDQ
16h 30m
MIA

08/12/25

DTW
American Airlines Logo
American Airlines

09/10/25

DTW
14h 30m
CLT
MIA

09/10/25

SDQ
$728
American Airlines Logo
American Airlines

08/12/25

SDQ
14h 44m
MIA
CLT

08/13/25

DTW
American Airlines Logo
American Airlines

09/10/25

DTW
14h 30m
DCA
MIA

09/10/25

SDQ
$728
American Airlines Logo
American Airlines

07/23/25

SDQ
27h 55m
MIA

07/24/25

DTW
American Airlines Logo
American Airlines

07/30/25

DTW
8h 41m
DCA
MIA

07/30/25

SDQ
$741
Delta Air Lines Logo
Delta Air Lines

06/30/25

SDQ
13h 46m
JFK

07/01/25

DTW
Delta Air Lines Logo
Delta Air Lines

07/12/25

DTW
17h 57m
JFK

07/13/25

SDQ
$921
Delta Air Lines Logo
Delta Air Lines

06/28/25

SDQ
13h 15m
JFK

06/28/25

DTW
Delta Air Lines Logo
Delta Air Lines

07/19/25

DTW
14h 55m
JFK

07/20/25

SDQ
$942
Delta Air Lines Logo
Delta Air Lines

06/27/25

SDQ
15h 57m
JFK

06/27/25

DTW
Delta Air Lines Logo
Delta Air Lines

07/18/25

DTW
14h 55m
JFK

07/19/25

SDQ
$1179
Delta Air Lines Logo
Delta Air Lines

06/27/25

SDQ
13h 46m
JFK

06/28/25

DTW
Delta Air Lines Logo
Delta Air Lines

07/18/25

DTW
21h 35m
CVG
JFK

07/19/25

SDQ
$1719

Top Deals on flights from Santo Domingo to Detroit

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

Spirit Airlines Logo
Spirit Airlines

Jul 24

SDQ
13h 33m
FLL

Jul 25

DTW

as low as

$222

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

Spirit Airlines Logo
Spirit Airlines

Jul 24

SDQ
28h 53m
FLL

Jul 25

DTW

as low as

$230

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

Spirit Airlines Logo
Spirit Airlines

Jul 24

SDQ
23h 28m
FLL

Jul 25

DTW

as low as

$230

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

Frontier Airlines Logo
Frontier Airlines

Jul 24

SDQ
20h 57m
MCO

Jul 25

DTW

as low as

$260

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 24

SDQ
10h
EWR

Jul 24

DTW

as low as

$300

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 24

SDQ
17h 25m
EWR

Jul 24

DTW

as low as

$300

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 24

SDQ
7h 50m
EWR

Jul 24

DTW

as low as

$300

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Jul 24

SDQ
16h 15m
MIA

Jul 24

DTW

as low as

$315

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Jul 24

SDQ
11h 44m
MIA
CLT

Jul 24

DTW

as low as

$319

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Jul 24

SDQ
15h 56m
MIA
CLT

Jul 25

DTW

as low as

$319

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

JetBlue Logo
JetBlue

Jul 24

SDQ
24h 54m
JFK

Jul 25

DTW

as low as

$321

Santo Domingo, DO (SDQ) - Detroit, US (DTT)

JetBlue Logo
JetBlue

Jul 24

SDQ
26h 29m
JFK

Jul 25

DTW

as low as

$321

Frequently Asked Questions

Is there a direct flight from Santo Domingo to Detroit?
There is no direct flight from Santo Domingo to Detroit. The available flights have one or two stops with airlines such as Spirit Airlines, Delta Air Lines, American Airlines, Frontier Airlines, and JetBlue.
Are there convenient layover flights from Santo Domingo to Detroit?
Yes, there are convenient layover flights available. Airlines include Spirit Airlines at $398, Frontier Airlines at $462, JetBlue at $536, Delta Air Lines at $601, and American Airlines at $620 for 1 stop flights. A 2 stop option is American Airlines at $700.
What are the most convenient layover airports for the flight?
For your flight from Santo Domingo to Detroit, convenient layover airports include Fort Lauderdale Hollywood International Airport, Hartsfield Jackson Atlanta International Airport, New York John F Kennedy Airport, and Miami International Airport.
What is the cheapest and fastest flight from Santo Domingo to Detroit?
The cheapest flight is with Spirit Airlines for $398, taking 13 hours 33 minutes. The fastest option is with Delta Air Lines for $601, taking 9 hours 6 minutes.
What are all possible destination arrival airports?
Possible destination arrival airports include: Detroit Metropolitan Airport, Fort Lauderdale-Hollywood International Airport, New York John F. Kennedy Airport, Hartsfield-Jackson Atlanta International Airport, and Miami International Airport.
What is the time difference between destination and arrival?
The time difference between Santo Domingo and Detroit is typically one hour, with Detroit being one hour behind Santo Domingo.
Priceline Phone Deals

Book with an agent for great rates!
Call now!

1 (888) 775-6158