Mexico — flights from Louisville to Mexico

Flight Deals from Louisville to Mexico from $207

Bundle + Save
Incredible Deals

Save up to 50% on select flights with Priceline

Bundle & Save

Save an average of $240 per person when bundling your flight and hotel together with Priceline

Best Price Guarantee

If a VIP member finds a better price elsewhere, we’ll refund up to 200% of the difference

Help 24/7

We’re always here for you — reach us 24 hours a day, 7 days a week

Good to Know

Cheapest fares and when to fly, by destination city — select a row for the details.

DestinationCheapest RTCheapest OWGood Deal PriceBest Time to FlyBest Day to FlyWhen to Book
$485$207$580AfternoonTuesday5 weeks
$491$258$531MiddayTuesday5 weeks
$651$450$737MiddayTuesday5 weeks
$649$297$688MiddayTuesday5 weeks
$667$552$772MorningTuesday5 weeks
$679$440$720MiddayTuesday5 weeks
$597$395$724EveningTuesday5 weeks
Methodology: learn how we calculate these figures

The best day to fly and how far ahead to book shown in this table are built from the prices Priceline customers actually paid for flights to this destination over the past 12 months or more.

Where a route has too few bookings to fill a figure, we borrow the shape from a group of routes with similar price behavior and fit it to the fares booked on that route.

Because past fares don’t reflect today’s market, we then adjust the historical prices for current conditions such as inflation and fuel costs, using the round-trip fares found in recent searches.

The cheapest round-trip and one-way fares, the good-deal price and the best time of day to fly come directly from the fares found in recent searches, not from historical bookings.

Southwest AirlinesSouthwest Airlinesfound Oct 7
11/04/26
2:05 pm
SDFLouisville Muhammad Ali International Airport
20h 10mMDWChicago Midway AirportMCIKansas City International Airport
11/05/26
10:15 am
CUNCancún International Airport
11/11/26
6:00 pm
CUNCancún International Airport
16h 5mMDWChicago Midway Airport
11/12/26
10:05 am
SDFLouisville Muhammad Ali International Airport
$485
Southwest AirlinesSouthwest Airlinesfound Oct 12
11/10/26
6:50 am
SDFLouisville Muhammad Ali International Airport
8h 20mDENDenver International Airport
11/10/26
1:10 pm
SJDLos Cabos International Airport
11/17/26
2:45 pm
SJDLos Cabos International Airport
17h 45mHOUWilliam P Hobby AirportMDWChicago Midway Airport
11/18/26
10:30 am
SDFLouisville Muhammad Ali International Airport
$491
American AirlinesAmerican Airlinesfound Oct 6
11/03/26
4:35 pm
SDFLouisville Muhammad Ali International Airport
6h 20mCLTCharlotte Douglas International Airport
11/03/26
9:55 pm
MEXLicenciado Benito Juarez International Airport
11/10/26
11:00 am
MEXLicenciado Benito Juarez International Airport
6h 26mDFWDallas Fort Worth International Airport
11/10/26
6:26 pm
SDFLouisville Muhammad Ali International Airport
$651
American AirlinesAmerican Airlinesfound Oct 19
11/13/26
6:01 am
SDFLouisville Muhammad Ali International Airport
6h 23mDFWDallas Fort Worth International Airport
11/13/26
11:24 am
PVRLicenciado Gustavo Díaz Ordaz International Airport
11/20/26
4:55 pm
PVRLicenciado Gustavo Díaz Ordaz International Airport
6h 20mDFWDallas Fort Worth International Airport
11/21/26
12:15 am
SDFLouisville Muhammad Ali International Airport
$649
Flight plus hotel
BUNDLE + SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

American AirlinesAmerican Airlinesfound Oct 12
11/10/26
6:01 am
SDFLouisville Muhammad Ali International Airport
5h 56mDFWDallas Fort Worth International Airport
11/10/26
10:57 am
BJXDel Bajío International Airport
11/17/26
6:05 am
BJXDel Bajío International Airport
8h 25mDFWDallas Fort Worth International Airport
11/17/26
3:30 pm
SDFLouisville Muhammad Ali International Airport
$667
American AirlinesAmerican Airlinesfound Oct 12
11/10/26
6:01 am
SDFLouisville Muhammad Ali International Airport
6h 40mDFWDallas Fort Worth International Airport
11/10/26
11:41 am
GDLDon Miguel Hidalgo Y Costilla International Airport
11/17/26
12:55 pm
GDLDon Miguel Hidalgo Y Costilla International Airport
7h 4mDFWDallas Fort Worth International Airport
11/17/26
8:59 pm
SDFLouisville Muhammad Ali International Airport
$679
American AirlinesAmerican Airlinesfound Oct 12
11/10/26
7:10 am
SDFLouisville Muhammad Ali International Airport
7h 15mDFWDallas Fort Worth International Airport
11/10/26
2:25 pm
CZMCozumel International Airport
11/17/26
3:18 pm
CZMCozumel International Airport
8h 16mDFWDallas Fort Worth International Airport
11/17/26
11:34 pm
SDFLouisville Muhammad Ali International Airport
$597
Southwest AirlinesSouthwest Airlinesfound Oct 7
11/04/26
2:05 pm
SDFLouisville Muhammad Ali International Airport
20h 10mMDWChicago Midway AirportMCIKansas City International Airport
11/05/26
10:15 am
CUNCancún International Airport
11/11/26
5:35 pm
CUNCancún International Airport
17h 35mHOUWilliam P Hobby AirportTPATampa International Airport
11/12/26
11:10 am
SDFLouisville Muhammad Ali International Airport
$485
Southwest AirlinesSouthwest Airlinesfound Oct 7
11/04/26
2:05 pm
SDFLouisville Muhammad Ali International Airport
20h 10mMDWChicago Midway AirportMCIKansas City International Airport
11/05/26
10:15 am
CUNCancún International Airport
11/11/26
5:05 pm
CUNCancún International Airport
18h 5mAUSAustin Bergstrom International AirportTPATampa International Airport
11/12/26
11:10 am
SDFLouisville Muhammad Ali International Airport
$485
Southwest AirlinesSouthwest Airlinesfound Oct 7
11/04/26
2:05 pm
SDFLouisville Muhammad Ali International Airport
20h 10mMDWChicago Midway AirportMCIKansas City International Airport
11/05/26
10:15 am
CUNCancún International Airport
11/11/26
3:30 pm
CUNCancún International Airport
20h 0mMCIKansas City International AirportMCOOrlando International Airport
11/12/26
11:30 am
SDFLouisville Muhammad Ali International Airport
$485

Best Mexico Hotel + Flight Packages

Best Mexico Hotel + Flight + Car Packages

When is the cheapest time to fly?

Cheapest in late January at about $596

Fares from Louisville to Mexico are lowest in late January, around $596, and September is the cheapest month overall, averaging $616. They peak in late December at about $781, $185 more than the low. The yearly average is $660.

JanFebMarAprMayJunJulAugSepOctNovDec$0$100$200$300$400$500$600$700$800$900
Show the data
When is the cheapest time to fly?
MonthAverage fareEarly monthLate month
January$619$643$596
February$622$607$638
March$693$681$703
April$652$670$634
May$654$630$676
June$710$702$717
July$699$710$689
August$641$659$624
September$616$615$617
October$627$631$623
November$653$639$666
December$737$690$781

How far in advance should I book?

Cheapest about 5 weeks out at $627

Book about 5 weeks before departure for the best fares from Louisville to Mexico, around $627. Booking in the final days before the flight costs about $750, $123 more. Booking six months ahead runs about $976.

1w2w1mo2mo3mo4mo5mo$0$200$400$600$800$1000
Show the data
How far in advance should I book? (selected points, lowest and highest included)
Days before departureAverage fare
180 days$976
172 days$973
164 days$960
156 days$934
148 days$910
140 days$888
132 days$866
124 days$844
116 days$820
108 days$794
100 days$770
92 days$745
84 days$721
76 days$695
68 days$673
2mo$653
52 days$640
44 days$631
38 days$627
36 days$627
28 days$631
20 days$651
12 days$693
4 days$734
0 days$750

What's the cheapest day of the week to fly?

Tuesday is the cheapest day of the week to fly from Louisville to Mexico. At $750 it is 6% cheaper than the average day. Friday is the most expensive day, 5% above average.

$805Sun$774Mon$750Tue$767Wed$820Thu$833Fri$824Sat
Show the data
What's the cheapest day of the week to fly?
DayAverage fare
Sun$805
Mon$774
Tue$750
Wed$767
Thu$820
Fri$833
Sat$824

When is the best time of day to fly?

Midday (12pm - 2pm) is the cheapest time of day to fly from Louisville to Mexico. At $685 it is 10% cheaper than the average time. Morning (5am - 12pm) is the most expensive time, 9% above average.

$827Morning$685Midday$775Afternoon$751Evening
Show the data
When is the best time of day to fly?
Time of dayAverage fare
Morning$827
Midday$685
Afternoon$775
Evening$751

What do round-trip flights from Louisville to Mexico cost?

Share of fares in each price range, adjusted to current prices.

1%$0to $30017%$300to $60040%$600to $90021%$900to $1,20013%$1,200to $1,5004%$1,500to $1,8004%$1,800and up
Show the data
What do round-trip flights from Louisville to Mexico cost?
Price rangeShare of fares
$0 to $3001%
$300 to $60017%
$600 to $90040%
$900 to $1,20021%
$1,200 to $1,50013%
$1,500 to $1,8004%
$1,800 and up4%
Methodology: learn how we calculate these charts

The charts “When is the cheapest time to fly?”, “How far in advance should I book?”, “What's the cheapest day of the week to fly?” and “What do round-trip flights from Louisville to Mexico cost?” are built from the prices Priceline customers actually paid for flights on this route over the past 12 months or more.

Where a route has too few bookings to fill every point in a chart, we borrow the shape of the curve from a group of routes with similar price behavior and fit it to the fares booked on this route.

Because past fares don’t reflect today’s market, we then adjust the historical prices for current conditions such as inflation and fuel costs, using the round-trip fares found in recent searches on this route.

The chart “When is the best time of day to fly?” is calculated directly from the fares found in recent searches, not from historical bookings.

Frequently Asked Questions

Everything you need to know about flying from Louisville to Mexico.

When is the cheapest time to fly from Louisville to Mexico?

The cheapest months to fly from Louisville to Cancun are September (7% below the yearly average), January, and February, with the half-month low falling in late January. The priciest months are December (12% above average) and June, with the highest half-month prices in late December.
Methodology
These seasonal fares look at the busiest city-to-city routes between the two places (up to four, chosen by scheduled flights) and at the seasonal fare curve Priceline's own archive provides for each route. Months are ranked by how far each month's average fare sits above or below that route's yearly average, taking the middle value across the routes, so one expensive route cannot dominate.

How far in advance should I book flights from Louisville to Mexico?

The best time to book flights from Louisville to Mexico is about 5 weeks before departure, based on fares between Louisville and Cancún. Booking very early, around 25 weeks out, tends to be the priciest.
Methodology
This booking-window guidance looks at the busiest city-to-city routes between the two places (up to four, chosen by scheduled flights) and at the booking-window fare curve Priceline's own archive provides for each route. The best time to book is the middle value of those routes' cheapest lead times.

What are the most popular cities to visit in Mexico?

From Louisville, Mexico's top gateways are Mexico City for culture and food, Cancun for Caribbean beaches, and Guadalajara or Monterrey for business and regional travel. From Cancun, short flights reach Tulum, Cozumel and Merida.

When is the best time of year to visit Mexico?

For Mexico, November to April offers dry, mild weather in cities like Mexico City, Cancun and Guadalajara, with lower humidity than summer. Summer brings heat and rain in many areas, and coastal resorts are busiest during U.S. school holidays.

How do I get to Muhammad Ali Intl Airport from the city center?

From downtown Louisville, the fastest way to reach Muhammad Ali International Airport is by taxi or rideshare, which typically takes 15 to 20 minutes depending on traffic. The TARC public bus system offers affordable service via route 2, with a stop at the airport and a journey of about 7 miles from the city center. Many local hotels also provide shuttle services, and parking is available near the terminal in a garage, surface lot, or credit card lot for those driving themselves. Rideshare and taxis are the most popular and efficient options, while the bus is the budget-friendly choice.
References