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Flight Deals from San Antonio to Medellin from $139

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Stops

  • Up to 1 stop
    $565
  • Up to 2 stops
    $650

Airlines

  • Aeromexico
    $613
  • American Airlines
    $646
  • LATAM Airlines Group
    $916
  • United Airlines
    $565

Cabin Class

  • Economy
    $565

Departure Airports

  • San Antonio International Airport
    $565

Arrival Airports

  • Jose Maria Córdova International Airport
    $565

Layover Airports

  • Dallas Fort Worth International Airport
    $650
  • El Dorado International Airport
    $916
  • George Bush Intercontinental Houston Airport
    $565
  • Hartsfield Jackson Atlanta International Airport
    $916
  • Licenciado Benito Juarez International Airport
    $613
  • Miami International Airport
    $646

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United Airlines Logo
United Airlines

11/25/25

SAT
12h 20m
IAH

11/25/25

MDE
United Airlines Logo
United Airlines

12/13/25

MDE
9h 15m
IAH

12/13/25

SAT
$565
Aeromexico Logo
Aeromexico

11/25/25

SAT
11h 43m
MEX

11/26/25

MDE
Aeromexico Logo
Aeromexico

12/13/25

MDE
9h 14m
MEX

12/13/25

SAT
$613
American Airlines Logo
American Airlines

11/01/25

SAT
7h 20m
MIA

11/01/25

MDE
American Airlines Logo
American Airlines

11/15/25

MDE
14h 32m
MIA

11/15/25

SAT
$646
American Airlines Logo
American Airlines

11/01/25

SAT
10h 23m
DFW
MIA

11/01/25

MDE
American Airlines Logo
American Airlines

11/15/25

MDE
12h 11m
MIA
DFW

11/15/25

SAT
$650
American Airlines Logo
American Airlines

11/01/25

SAT
10h 23m
DFW
MIA

11/01/25

MDE
American Airlines Logo
American Airlines

11/15/25

MDE
14h 32m
MIA

11/15/25

SAT
$650
American Airlines Logo
American Airlines

11/25/25

SAT
17h 24m
MIA

11/25/25

MDE
American Airlines Logo
American Airlines

12/13/25

MDE
9h 9m
MIA

12/13/25

SAT
$669
LATAM Airlines Group Logo
LATAM Airlines Group

11/01/25

SAT
10h 45m
ATL
BOG

11/01/25

MDE
LATAM Airlines Group Logo
LATAM Airlines Group

11/15/25

MDE
19h 15m
BOG
ATL

11/16/25

SAT
$916
LATAM Airlines Group Logo
LATAM Airlines Group

11/01/25

SAT
12h 30m
ATL
BOG

11/01/25

MDE
LATAM Airlines Group Logo
LATAM Airlines Group

11/15/25

MDE
19h 15m
BOG
ATL

11/16/25

SAT
$1045
LATAM Airlines Group Logo
LATAM Airlines Group

11/01/25

SAT
6h 51m
IAH

11/01/25

MDE
LATAM Airlines Group Logo
LATAM Airlines Group

11/15/25

MDE
11h 5m
BOG
ATL

11/15/25

SAT
$1721

Top Deals on flights from San Antonio to Medellin

San Antonio, US (SAT) - Medellin, CO (MDE)

 Logo

Sep 15

SAT
18h 15m
FLL

Sep 16

MDE

as low as

$139

San Antonio, US (SAT) - Medellin, CO (MDE)

 Logo

Sep 28

SAT
18h 15m
FLL

Sep 29

MDE

as low as

$139

San Antonio, US (SAT) - Medellin, CO (MDE)

 Logo

Sep 12

SAT
18h 15m
FLL

Sep 13

MDE

as low as

$139

San Antonio, US (SAT) - Medellin, CO (MDE)

 Logo

Oct 3

SAT
18h 15m
FLL

Oct 4

MDE

as low as

$139

San Antonio, US (SAT) - Medellin, CO (MDE)

United Airlines Logo
United Airlines

Sep 15

SAT
13h 55m
IAH

Sep 15

MDE

as low as

$260

San Antonio, US (SAT) - Medellin, CO (MDE)

American Airlines Logo
American Airlines

Sep 15

SAT
13h 15m
DFW
MIA

Sep 15

MDE

as low as

$299

San Antonio, US (SAT) - Medellin, CO (MDE)

American Airlines Logo
American Airlines

Sep 15

SAT
7h 28m
MIA

Sep 15

MDE

as low as

$299

San Antonio, US (SAT) - Medellin, CO (MDE)

 Logo

Sep 15

SAT
11h 40m
IAH
SAL

Sep 16

MDE

as low as

$316

San Antonio, US (SAT) - Medellin, CO (MDE)

 Logo

Sep 15

SAT
15h 53m
ATL
BOG

Sep 15

MDE

as low as

$583

San Antonio, US (SAT) - Medellin, CO (MDE)

LATAM Airlines Group Logo
LATAM Airlines Group

Sep 15

SAT
12h 11m
ATL
BOG

Sep 15

MDE

as low as

$684

San Antonio, US (SAT) - Medellin, CO (MDE)

United Airlines Logo
United Airlines

Sep 15

SAT
11h 6m
IAH
PTY

Sep 15

MDE

as low as

$754

San Antonio, US (SAT) - Medellin, CO (MDE)

 Logo

Sep 15

SAT
21h 45m
IAH
PTY

Sep 16

MDE

as low as

$808

Frequently Asked Questions

What is the cheapest and fastest flight from San Antonio to Medellin?
The cheapest flight is with United Airlines at $565, taking 12 hours 20 minutes. The fastest flight is with LATAM Airlines Group at $1721, taking 6 hours 51 minutes.
What are all possible destination arrival airports?
The destination arrival airport is Jose Maria Córdova International Airport.
What is the time difference between destination and arrival?
The time difference between San Antonio and Medellin is typically one hour, with Medellin in the Colombia Time Zone, which does not observe Daylight Saving Time.
Is there a direct flight from San Antonio to Medellin?
There is no direct flight from San Antonio to Medellin. The available options include 1 stop flights with United Airlines at $565, Aeromexico at $613, American Airlines at $646, and LATAM Airlines Group at $1721.
Are there convenient layover flights from San Antonio to Medellin?
Yes, convenient 1 stop flights are available from San Antonio to Medellin with United Airlines at $565, Aeromexico at $613, American Airlines at $646, and LATAM Airlines Group at $1721. Additionally, 2 stops flights are offered by American Airlines at $650 and LATAM Airlines Group at $916.
What are the most convenient layover airports for my flight?
For your flight from San Antonio to Medellin, the most convenient layover airports are George Bush Intercontinental Houston (United, LATAM), Licenciado Benito Juarez International (Aeromexico), and Miami International (American Airlines).
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