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Flight Deals from San Diego to Santiago from $235

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Stops

  • Up to 1 stop
    $494
  • Up to 2 stops
    $579

Airlines

  • American Airlines
    $579
  • JetBlue
    $494
  • United Airlines
    $601

Cabin Class

  • Economy
    $494

Departure Airports

  • Mc Clellan-Palomar Airport
    $579
  • San Diego International Airport
    $494

Arrival Airports

  • Cibao International Airport
    $494

Layover Airports

  • Charlotte Douglas International Airport
    $585
  • Chicago O Hare Airport
    $605
  • Dallas Fort Worth International Airport
    $579
  • Denver International Airport
    $605
  • George Bush Intercontinental Houston Airport
    $605
  • Luis Munoz Marin International Airport
    $592
  • Miami International Airport
    $579
  • New York John F Kennedy Airport
    $494
  • Newark Liberty Airport
    $601
  • Orlando International Airport
    $622
  • Phoenix Sky Harbor International Airport
    $579
  • San Francisco International Airport
    $605

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On average save $240 per traveler
JetBlue Logo
JetBlue

09/10/25

SAN
12h 7m
JFK

09/11/25

STI
JetBlue Logo
JetBlue

09/17/25

STI
17h 14m
JFK

09/17/25

SAN
$494
JetBlue Logo
JetBlue

09/10/25

SAN
14h 40m
JFK

09/11/25

STI
JetBlue Logo
JetBlue

09/17/25

STI
17h 14m
JFK

09/17/25

SAN
$494
JetBlue Logo
JetBlue

09/10/25

SAN
12h 7m
JFK

09/11/25

STI
JetBlue Logo
JetBlue

09/17/25

STI
16h 47m
JFK

09/18/25

SAN
$540
JetBlue Logo
JetBlue

09/10/25

SAN
14h 40m
JFK

09/11/25

STI
JetBlue Logo
JetBlue

09/17/25

STI
16h 47m
JFK

09/18/25

SAN
$540
American Airlines Logo
American Airlines

09/10/25

CLD
21h 2m
PHX
MIA

09/11/25

STI
American Airlines Logo
American Airlines

09/17/25

STI
11h 29m
MIA

09/17/25

SAN
$579
American Airlines Logo
American Airlines

09/10/25

CLD
21h 2m
PHX
MIA

09/11/25

STI
American Airlines Logo
American Airlines

09/17/25

STI
12h 7m
MIA
DFW

09/17/25

SAN
$579
American Airlines Logo
American Airlines

09/10/25

CLD
21h 2m
PHX
MIA

09/11/25

STI
American Airlines Logo
American Airlines

09/17/25

STI
23h 32m
MIA
DFW

09/18/25

SAN
$585
American Airlines Logo
American Airlines

09/10/25

CLD
21h 2m
PHX
MIA

09/11/25

STI
American Airlines Logo
American Airlines

09/17/25

STI
21h 55m
MIA
DFW

09/18/25

SAN
$585
American Airlines Logo
American Airlines

09/10/25

CLD
21h 2m
PHX
MIA

09/11/25

STI
American Airlines Logo
American Airlines

09/17/25

STI
24h 25m
MIA
CLT

09/18/25

SAN
$585
American Airlines Logo
American Airlines

09/10/25

CLD
21h 2m
PHX
MIA

09/11/25

STI
American Airlines Logo
American Airlines

09/17/25

STI
22h 58m
MIA
CLT

09/18/25

SAN
$585
JetBlue Logo
JetBlue

09/10/25

SAN
12h 7m
JFK

09/11/25

STI
JetBlue Logo
JetBlue

09/17/25

STI
32h 30m
SJU
JFK

09/18/25

SAN
$592
JetBlue Logo
JetBlue

09/10/25

SAN
14h 40m
JFK

09/11/25

STI
JetBlue Logo
JetBlue

09/17/25

STI
32h 30m
SJU
JFK

09/18/25

SAN
$592
United Airlines Logo
United Airlines

09/10/25

SAN
13h 56m
EWR

09/10/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 8m
EWR

09/17/25

SAN
$601
United Airlines Logo
United Airlines

09/10/25

SAN
12h 16m
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 8m
EWR

09/17/25

SAN
$601
United Airlines Logo
United Airlines

09/10/25

SAN
13h 32m
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 8m
EWR

09/17/25

SAN
$601
United Airlines Logo
United Airlines

09/10/25

SAN
14h 31m
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 8m
EWR

09/17/25

SAN
$601
United Airlines Logo
United Airlines

09/10/25

SAN
11h 17m
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
19h 14m
EWR
DEN

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
13h 56m
EWR

09/10/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 41m
EWR
IAH

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
13h 32m
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
19h 14m
EWR
DEN

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
13h 42m
ORD
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 41m
EWR
IAH

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
13h 46m
SFO
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
19h 14m
EWR
DEN

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
12h 16m
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
22h 28m
EWR
ORD

09/18/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
13h 46m
SFO
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 41m
EWR
IAH

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
13h 46m
DEN
EWR

09/10/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 41m
EWR
IAH

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
14h 36m
SFO
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 8m
EWR

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
14h 31m
IAH
EWR

09/10/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 8m
EWR

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
16h 51m
SFO
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
18h 8m
EWR

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
13h 42m
ORD
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
19h 14m
EWR
DEN

09/17/25

SAN
$605
United Airlines Logo
United Airlines

09/10/25

SAN
11h 17m
EWR

09/11/25

STI
United Airlines Logo
United Airlines

09/17/25

STI
22h 28m
EWR
ORD

09/18/25

SAN
$605
JetBlue Logo
JetBlue

09/10/25

SAN
14h 40m
JFK

09/11/25

STI
JetBlue Logo
JetBlue

09/17/25

STI
25h 51m
MCO
JFK

09/18/25

SAN
$622

Top Deals on flights from San Diego to Santiago

San Diego, US (SAN) - Santiago, DO (STI)

JetBlue Logo
JetBlue

Sep 10

SAN
12h 7m
JFK

Sep 11

STI

as low as

$235

San Diego, US (SAN) - Santiago, DO (STI)

JetBlue Logo
JetBlue

Sep 10

SAN
14h 40m
JFK

Sep 11

STI

as low as

$235

San Diego, US (SAN) - Santiago, DO (STI)

American Airlines Logo
American Airlines

Sep 10

CLD
21h 2m
PHX
MIA

Sep 11

STI

as low as

$278

San Diego, US (SAN) - Santiago, DO (STI)

American Airlines Logo
American Airlines

Sep 10

SAN
20h 25m
CLT
MIA

Sep 11

STI

as low as

$282

San Diego, US (SAN) - Santiago, DO (STI)

American Airlines Logo
American Airlines

Sep 10

SAN
10h 55m
CLT
MIA

Sep 11

STI

as low as

$282

San Diego, US (SAN) - Santiago, DO (STI)

American Airlines Logo
American Airlines

Sep 10

SAN
20h 49m
DFW
MIA

Sep 11

STI

as low as

$282

San Diego, US (SAN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Sep 10

SAN
14h 36m
SFO
EWR

Sep 11

STI

as low as

$289

San Diego, US (SAN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Sep 10

SAN
14h 31m
IAH
EWR

Sep 10

STI

as low as

$289

San Diego, US (SAN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Sep 10

SAN
17h 40m
DEN
EWR

Sep 11

STI

as low as

$289

San Diego, US (SAN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Sep 10

SAN
15h 25m
DEN
EWR

Sep 11

STI

as low as

$289

San Diego, US (SAN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Sep 10

SAN
22h 16m
ORD
EWR

Sep 11

STI

as low as

$289

San Diego, US (SAN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Sep 10

SAN
13h 42m
ORD
EWR

Sep 11

STI

as low as

$289

Frequently Asked Questions

What are all possible destination arrival airports?
The possible destination arrival airport is Cibao International Airport. Layover airports for flights include New York John F Kennedy Airport, Miami International Airport, Newark Liberty Airport, and San Francisco International Airport.
What is the time difference between destination and arrival?
The time difference between San Diego and Santiago is typically 3 hours, with Santiago being ahead of San Diego.
Is there a direct flight from San Diego to Santiago?
There is no direct flight from San Diego to Santiago. The available flights include 1 stop with JetBlue at $494, American Airlines at $626, and United Airlines at $601, each with layovers.
Are there convenient layover flights from San Diego to Santiago?
Yes, convenient 1 stop flights include JetBlue at $494 (12h 7m, layover at New York JFK), United Airlines at $601 (14h 31m, layover at Newark), and American Airlines at $626 (10h 42m, layover at Miami).
What are the most convenient layover airports for my flight?
The most convenient layover airports are New York John F Kennedy, Miami International, and Newark Liberty, which are well-connected for your flight from San Diego to Santiago.
What are the cheapest and fastest flights from San Diego to Santiago?
The cheapest flight is with JetBlue for $494, 12h 7m. The fastest flight is with American Airlines for $626, 10h 42m. Airlines include JetBlue, United Airlines, and American Airlines.
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