Flight Deals from San Diego to Mayagueez from $381
Top flight deals from leading airlines:
... and +100s more
Save up to 50% on select flights with Priceline
Save an average of $240 per person when bundling your flight and hotel together with Priceline
If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference
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Stops
- Up to 2 stops$772
Airlines
- JetBlue$772
- United Airlines$1426
Cabin Class
- Economy$772
Departure Airports
- San Diego International Airport$772
Arrival Airports
- Eugenio Maria De Hostos Airport$772
Layover Airports
- Chicago O Hare Airport$1549
- General Edward Lawrence Logan International Airport$772
- George Bush Intercontinental Houston Airport$1540
- Luis Munoz Marin International Airport$772
- New York John F Kennedy Airport$772
- Newark Liberty Airport$1426
- Washington Dulles Airport$1426
Best Price. GUARANTEED.
Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.
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07/29/25
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Top Deals on flights from San Diego to Mayagueez
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$381
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$391
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$471
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$481
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$488
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$778
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$778
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$778
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$908
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$908
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$928
San Diego, US (SAN) - Mayagueez, PR (MAZ)
Jul 28
Jul 29
as low as
$928
Flights to Mayagueez
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