
Flight Deals from Panama City to Knoxville from $340
Top flight deals from leading airlines:







... and +100s more
Save up to 50% on select flights with Priceline
Save an average of $240 per person when bundling your flight and hotel together with Priceline
If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference
We’re always here for you - reach us 24 hours a day, 7 days a week
Stops
- Up to 1 stop$533
- Up to 2 stops$729
Airlines
- American Airlines$725
- COPA Airlines$2042
- United Airlines$533
Cabin Class
- Economy$533
Departure Airports
- Tocumen International Airport$533
Arrival Airports
- McGhee Tyson Airport$533
Layover Airports
- Charlotte Douglas International Airport$729
- George Bush Intercontinental Houston Airport$533
- Miami International Airport$725
- Philadelphia International Airport$849
- Reagan Washington National Airport$729
- Washington Dulles Airport$2042
Best Price. GUARANTEED.
Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

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Top Deals on flights from Panama City to Knoxville
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 2
as low as
$340
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 1
as low as
$400
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 1
as low as
$400
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 1
as low as
$441
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 2
as low as
$447
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 1
as low as
$589
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 1
as low as
$589
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 2
as low as
$618
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 2
as low as
$618
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 2
as low as
$1119
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 2
as low as
$1119
Panama City, PA (PTY) - Knoxville, US (TYS)

Aug 1
Aug 1
as low as
$1119
Flights to Knoxville
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