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Flight Deals from Puerto Rico to Santiago from $257

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Top Deals on flights from San Juan to Santiago

San Juan, PR (SJU) - Santiago, DO (STI)

JetBlue Logo
JetBlue

Apr 23

SJU
1h 15m
Direct

Apr 23

STI
JetBlue Logo
JetBlue

Apr 26

STI
1h 11m
Direct

Apr 26

SJU

as low as

$257

San Juan, PR (SJU) - Santiago, DO (STI)

JetBlue Logo
JetBlue

Apr 13

SJU
1h 13m
Direct

Apr 13

STI
JetBlue Logo
JetBlue

Apr 17

STI
1h 11m
Direct

Apr 17

SJU

as low as

$257

San Juan, PR (SJU) - Santiago, DO (STI)

JetBlue Logo
JetBlue

Apr 19

SJU
1h 15m
Direct

Apr 19

STI
JetBlue Logo
JetBlue

Apr 22

STI
1h 11m
Direct

Apr 22

SJU

as low as

$257

San Juan, PR (SJU) - Santiago, DO (STI)

American Airlines Logo
American Airlines

May 1

SJU
6h 38m
MIA

May 1

STI
American Airlines Logo
American Airlines

May 4

STI
21h 21m
MIA

May 5

SJU

as low as

$720

San Juan, PR (SJU) - Santiago, DO (STI)

American Airlines Logo
American Airlines

Apr 27

SJU
6h 38m
MIA

Apr 27

STI
American Airlines Logo
American Airlines

May 4

STI
21h 21m
MIA

May 5

SJU

as low as

$720

San Juan, PR (SJU) - Santiago, DO (STI)

American Airlines Logo
American Airlines

Apr 17

SJU
6h 38m
MIA

Apr 17

STI
American Airlines Logo
American Airlines

Apr 19

STI
7h 52m
MIA

Apr 19

SJU

as low as

$759

San Juan, PR (SJU) - Santiago, DO (STI)

Hahn Air Logo
Hahn Air

Apr 2

SJU
9h 23m
PTY

Apr 2

STI
Hahn Air Logo
Hahn Air

Apr 16

STI
24h 10m
PTY

Apr 17

SJU

as low as

$816

San Juan, PR (SJU) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 19

SJU
14h 12m
EWR

Apr 19

STI
United Airlines Logo
United Airlines

Apr 22

STI
9h 43m
EWR

Apr 22

SJU

as low as

$877

San Juan, PR (SJU) - Santiago, DO (STI)

United Airlines Logo
United Airlines

May 1

SJU
14h 12m
EWR

May 1

STI
United Airlines Logo
United Airlines

May 4

STI
9h 43m
EWR

May 4

SJU

as low as

$926

San Juan, PR (SJU) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 7

SJU
9h 27m
EWR

Apr 7

STI
United Airlines Logo
United Airlines

Apr 16

STI
9h 43m
EWR

Apr 16

SJU

as low as

$931

San Juan, PR (SJU) - Santiago, DO (STI)

American Airlines Logo
American Airlines

Apr 30

SJU
21h 41m
PHL
MIA

May 1

STI
American Airlines Logo
American Airlines

May 6

STI
28h 38m
MIA

May 7

SJU

as low as

$4340

San Juan, PR (SJU) - Santiago, DO (STI)

American Airlines Logo
American Airlines

Apr 30

SJU
21h 41m
PHL
MIA

May 1

STI
American Airlines Logo
American Airlines

May 6

STI
21h 16m
MIA
CLT

May 7

SJU

as low as

$4522

Top Deals on flights from Aguadilla to Santiago

Aguadilla, PR (BQN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 26

BQN
14h 57m
EWR

Apr 26

STI
United Airlines Logo
United Airlines

May 3

STI
17h 9m
EWR

May 3

BQN

as low as

$1143

Aguadilla, PR (BQN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 26

BQN
12h 42m
EWR

Apr 26

STI
United Airlines Logo
United Airlines

May 3

STI
17h 9m
EWR

May 3

BQN

as low as

$1143

Aguadilla, PR (BQN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 26

BQN
22h 37m
EWR

Apr 26

STI
United Airlines Logo
United Airlines

May 3

STI
17h 9m
EWR

May 3

BQN

as low as

$1190

Aguadilla, PR (BQN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 26

BQN
12h 42m
EWR

Apr 26

STI
United Airlines Logo
United Airlines

May 3

STI
30h 46m
EWR

May 4

BQN

as low as

$1242

Aguadilla, PR (BQN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 26

BQN
14h 57m
EWR

Apr 26

STI
United Airlines Logo
United Airlines

May 3

STI
30h 46m
EWR

May 4

BQN

as low as

$1242

Aguadilla, PR (BQN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 26

BQN
22h 37m
EWR

Apr 26

STI
United Airlines Logo
United Airlines

May 3

STI
30h 46m
EWR

May 4

BQN

as low as

$1289

Aguadilla, PR (BQN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 26

BQN
12h 42m
EWR

Apr 26

STI
American Airlines Logo
American Airlines

May 3

STI
33h 37m
MIA
EWR

May 4

BQN

as low as

$7811

Aguadilla, PR (BQN) - Santiago, DO (STI)

United Airlines Logo
United Airlines

Apr 26

BQN
14h 57m
EWR

Apr 26

STI
American Airlines Logo
American Airlines

May 3

STI
33h 37m
MIA
EWR

May 4

BQN

as low as

$7811

Top Deals on flights from Culebra to Santiago

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
4h 42m
SJU

Apr 23

STI
JetBlue Logo
JetBlue

May 7

STI
15h 43m
SJU

May 8

CPX

as low as

$515

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
24h 9m
SJU

Apr 24

STI
JetBlue Logo
JetBlue

May 7

STI
15h 43m
SJU

May 8

CPX

as low as

$515

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
4h 42m
SJU

Apr 23

STI
JetBlue Logo
JetBlue

May 7

STI
17h 48m
SJU

May 8

CPX

as low as

$515

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
18h 57m
SJU
FLL

Apr 24

STI
JetBlue Logo
JetBlue

May 7

STI
15h 43m
SJU

May 8

CPX

as low as

$656

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
18h 57m
SJU
FLL

Apr 24

STI
JetBlue Logo
JetBlue

May 7

STI
17h 48m
SJU

May 8

CPX

as low as

$656

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
16h 17m
SJU
MCO

Apr 24

STI
JetBlue Logo
JetBlue

May 7

STI
15h 43m
SJU

May 8

CPX

as low as

$662

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
16h 17m
SJU
MCO

Apr 24

STI
JetBlue Logo
JetBlue

May 7

STI
17h 48m
SJU

May 8

CPX

as low as

$662

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
18h 57m
SJU
FLL

Apr 24

STI
JetBlue Logo
JetBlue

May 7

STI
17h 48m
SJU

May 8

CPX

as low as

$701

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
24h 9m
SJU

Apr 24

STI
JetBlue Logo
JetBlue

May 7

STI
18h 28m
BOS
SJU

May 8

CPX

as low as

$754

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
4h 42m
SJU

Apr 23

STI
JetBlue Logo
JetBlue

May 7

STI
18h 28m
BOS
SJU

May 8

CPX

as low as

$754

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
22h 39m
SJU

Apr 24

STI
JetBlue Logo
JetBlue

May 7

STI
18h 28m
BOS
SJU

May 8

CPX

as low as

$794

Culebra, PR (CPX) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 23

CPX
16h 17m
SJU
MCO

Apr 24

STI
JetBlue Logo
JetBlue

May 7

STI
18h 28m
BOS
SJU

May 8

CPX

as low as

$900

Top Deals on flights from Mayagueez to Santiago

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
5h 5m
SJU

Apr 27

STI
JetBlue Logo
JetBlue

May 4

STI
20h 22m
SJU

May 5

MAZ

as low as

$505

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
7h 37m
SJU

Apr 27

STI
JetBlue Logo
JetBlue

May 4

STI
17h 20m
SJU

May 5

MAZ

as low as

$505

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
5h 5m
SJU

Apr 27

STI
JetBlue Logo
JetBlue

May 4

STI
17h 20m
SJU

May 5

MAZ

as low as

$505

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
7h 37m
SJU

Apr 27

STI
JetBlue Logo
JetBlue

May 4

STI
20h 22m
SJU

May 5

MAZ

as low as

$505

Mayagueez, PR (MAZ) - Santiago, DO (STI)

JetBlue Logo
JetBlue

Apr 27

MAZ
5h 5m
SJU

Apr 27

STI
JetBlue Logo
JetBlue

May 4

STI
23h 49m
SJU

May 5

MAZ

as low as

$529

Mayagueez, PR (MAZ) - Santiago, DO (STI)

JetBlue Logo
JetBlue

Apr 27

MAZ
5h 5m
SJU

Apr 27

STI
JetBlue Logo
JetBlue

May 4

STI
20h 22m
SJU

May 5

MAZ

as low as

$529

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
39h 27m
SJU
FLL

Apr 29

STI
JetBlue Logo
JetBlue

May 4

STI
17h 20m
SJU

May 5

MAZ

as low as

$600

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
39h 27m
SJU
FLL

Apr 29

STI
JetBlue Logo
JetBlue

May 4

STI
20h 22m
SJU

May 5

MAZ

as low as

$600

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
14h 44m
SJU
MCO

Apr 28

STI
JetBlue Logo
JetBlue

May 4

STI
17h 20m
SJU

May 5

MAZ

as low as

$613

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
14h 44m
SJU
MCO

Apr 28

STI
JetBlue Logo
JetBlue

May 4

STI
20h 22m
SJU

May 5

MAZ

as low as

$613

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
33h 31m
SJU
BOS

Apr 29

STI
JetBlue Logo
JetBlue

May 4

STI
20h 22m
SJU

May 5

MAZ

as low as

$830

Mayagueez, PR (MAZ) - Santiago, DO (STI)

Cape Air Logo
Cape Air

Apr 27

MAZ
33h 31m
SJU
BOS

Apr 29

STI
JetBlue Logo
JetBlue

May 4

STI
17h 20m
SJU

May 5

MAZ

as low as

$830

Good to Know

Essential information to help you plan your flight from Puerto Rico to Santiago

Cheapest Flight

$257

The lowest price we found in the last two weeks, departing Apr 23 and returning Apr 26

Airline B61h 15m ‧ economy

Fastest Flights

$257

The fastest flight that we found in the last two weeks, departing Apr 13 and returning Apr 17

Airline B61h 13m ‧ economy

Cheapest Flight Round-trip

$257

Cheapest price found in the last 14 days, departing Apr 23 and returning Apr 26

Airline B61h 15m ‧ economy

Cheapest Layover airport

$505

The cheapest layover airport to Santiago is currently $505

Airline B61 stop ‧ 7h 37m ‧ economy

Best Arrival airport

$257

The best arrival airport to Santiago is currently $257

Airline B61h 15m ‧ economy

Best Departure airport

$257

The best departure airport to Santiago is currently $257

Airline B61h 15m ‧ economy

Cheapest Airline

$257

The cheapest airline to Santiago is currently $257

Airline B61h 15m ‧ economy

Flights to Santiago