$212 Flight Deals from Pittsburgh to Santiago

Top flight deals from leading airlines:

... and +100s more

Incredible Deals

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Stops

Up to 1 stop
$448
Up to 2 stops
$480

Airlines

American Airlines
$538
JetBlue
$448
United Airlines
$553

Cabin Class

Economy
$448

Departure Airports

Pittsburgh International Airport
$448

Arrival Airports

Cibao International Airport
$448

Layover Airports

Charlotte Douglas International Airport
$542
Chicago O Hare Airport
$542
General Edward Lawrence Logan International Airport
$480
George Bush Intercontinental Houston Airport
$557
Miami International Airport
$538
New York John F Kennedy Airport
$448
Newark Liberty Airport
$553
Reagan Washington National Airport
$542
Washington Dulles Airport
$557

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

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BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

JetBlue

09/13/25

6:05pm

PIT

14h 40m

JFK

09/14/25

8:45am

STI

JetBlue

09/20/25

5:15am

STI

11h 55m

JFK

09/20/25

5:10pm

PIT

^$448

JetBlue

09/13/25

6:00am

PIT

12h 4m

JFK

09/13/25

6:04pm

STI

JetBlue

09/20/25

3:20am

STI

13h 50m

JFK

09/20/25

5:10pm

PIT

^$448

JetBlue

09/13/25

6:00am

PIT

8h 20m

JFK

09/13/25

2:20pm

STI

JetBlue

09/20/25

5:15am

STI

11h 55m

JFK

09/20/25

5:10pm

PIT

^$448

JetBlue

09/13/25

6:00am

PIT

12h 4m

JFK

09/13/25

6:04pm

STI

JetBlue

09/20/25

5:15am

STI

11h 55m

JFK

09/20/25

5:10pm

PIT

^$448

JetBlue

09/13/25

6:00am

PIT

8h 20m

JFK

09/13/25

2:20pm

STI

JetBlue

09/20/25

3:20am

STI

13h 50m

JFK

09/20/25

5:10pm

PIT

^$448

JetBlue

09/13/25

6:00am

PIT

12h 4m

JFK

09/13/25

6:04pm

STI

JetBlue

09/20/25

5:15am

STI

9h 34m

JFK

BOS

09/20/25

2:49pm

PIT

^$480

JetBlue

09/13/25

6:00am

PIT

8h 20m

JFK

09/13/25

2:20pm

STI

JetBlue

09/20/25

3:20am

STI

11h 29m

JFK

BOS

09/20/25

2:49pm

PIT

^$480

JetBlue

09/13/25

6:00am

PIT

8h 20m

JFK

09/13/25

2:20pm

STI

JetBlue

09/20/25

5:15am

STI

13h 32m

JFK

BOS

09/20/25

6:47pm

PIT

^$480

JetBlue

09/13/25

6:00am

PIT

12h 4m

JFK

09/13/25

6:04pm

STI

JetBlue

09/20/25

3:20am

STI

15h 27m

JFK

BOS

09/20/25

6:47pm

PIT

^$480

JetBlue

09/13/25

7:00am

PIT

11h 4m

BOS

JFK

09/13/25

6:04pm

STI

JetBlue

09/20/25

3:20am

STI

13h 50m

JFK

09/20/25

5:10pm

PIT

^$480

American Airlines

09/13/25

6:10am

PIT

6h 17m

MIA

09/13/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

9h 19m

MIA

09/20/25

10:48pm

PIT

^$538

American Airlines

09/13/25

6:10am

PIT

6h 17m

MIA

09/13/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

22h

MIA

ORD

09/21/25

11:29am

PIT

^$542

American Airlines

09/13/25

6:47pm

PIT

17h 40m

CLT

MIA

09/14/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

20h 15m

MIA

DCA

09/21/25

9:44am

PIT

^$542

American Airlines

09/13/25

5:23pm

PIT

19h 4m

ORD

MIA

09/14/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

9h 34m

MIA

CLT

09/20/25

11:03pm

PIT

^$542

American Airlines

09/13/25

6:10am

PIT

6h 17m

MIA

09/13/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

20h 15m

MIA

DCA

09/21/25

9:44am

PIT

^$542

American Airlines

09/13/25

6:10am

PIT

6h 17m

MIA

09/13/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

22h 47m

MIA

ORD

09/21/25

12:16pm

PIT

^$542

American Airlines

09/13/25

3:06pm

PIT

21h 21m

CLT

MIA

09/14/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

20h 15m

MIA

DCA

09/21/25

9:44am

PIT

^$542

American Airlines

09/13/25

6:10am

PIT

6h 17m

MIA

09/13/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

20h 9m

MIA

CLT

09/21/25

9:38am

PIT

^$542

American Airlines

09/13/25

5:23pm

PIT

19h 4m

ORD

MIA

09/14/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

9h 19m

MIA

09/20/25

10:48pm

PIT

^$542

American Airlines

09/13/25

6:47pm

PIT

17h 40m

CLT

MIA

09/14/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

9h 19m

MIA

09/20/25

10:48pm

PIT

^$542

American Airlines

09/13/25

6:47pm

PIT

17h 40m

CLT

MIA

09/14/25

12:27pm

STI

American Airlines

09/20/25

1:29pm

STI

9h 34m

MIA

CLT

09/20/25

11:03pm

PIT

^$542

United Airlines

09/13/25

11:58am

PIT

11h 48m

EWR

09/13/25

11:46pm

STI

United Airlines

09/20/25

6:00am

STI

9h 27m

EWR

09/20/25

3:27pm

PIT

^$553

United Airlines

09/13/25

11:28am

PIT

12h 18m

EWR

09/13/25

11:46pm

STI

United Airlines

09/20/25

6:00am

STI

14h 54m

EWR

09/20/25

8:54pm

PIT

^$553

United Airlines

09/13/25

11:28am

PIT

12h 18m

EWR

09/13/25

11:46pm

STI

United Airlines

09/20/25

6:00am

STI

9h 27m

EWR

09/20/25

3:27pm

PIT

^$553

United Airlines

09/13/25

11:58am

PIT

11h 48m

EWR

09/13/25

11:46pm

STI

United Airlines

09/20/25

6:00am

STI

14h 54m

EWR

09/20/25

8:54pm

PIT

^$553

United Airlines

09/13/25

6:15am

PIT

8h 57m

IAD

EWR

09/13/25

3:12pm

STI

United Airlines

09/20/25

6:00am

STI

9h 27m

EWR

09/20/25

3:27pm

PIT

^$557

United Airlines

09/13/25

6:10am

PIT

17h 36m

IAH

EWR

09/13/25

11:46pm

STI

United Airlines

09/20/25

6:00am

STI

9h 27m

EWR

09/20/25

3:27pm

PIT

^$557

United Airlines

09/13/25

6:10am

PIT

17h 36m

IAH

EWR

09/13/25

11:46pm

STI

United Airlines

09/20/25

6:00am

STI

10h 55m

EWR

ORD

09/20/25

4:55pm

PIT

^$557

United Airlines

09/13/25

8:10pm

PIT

16h 47m

IAD

EWR

09/14/25

12:57pm

STI

United Airlines

09/20/25

6:00am

STI

9h 27m

EWR

09/20/25

3:27pm

PIT

^$557

United Airlines

09/13/25

6:15am

PIT

8h 57m

IAD

EWR

09/13/25

3:12pm

STI

United Airlines

09/20/25

6:00am

STI

14h 54m

EWR

09/20/25

8:54pm

PIT

^$557

Top Deals on flights from Pittsburgh to Santiago

Pittsburgh, US (PIT) - Santiago, DO (STI)

JetBlue

Sep 13

6:05pm

PIT

14h 40m

JFK

Sep 14

8:45am

STI

as low as

^$212

Pittsburgh, US (PIT) - Santiago, DO (STI)

JetBlue

Sep 13

6:00am

PIT

12h 4m

JFK

Sep 13

6:04pm

STI

as low as

^$215

Pittsburgh, US (PIT) - Santiago, DO (STI)

American Airlines

Sep 13

6:47pm

PIT

17h 40m

CLT

MIA

Sep 14

12:27pm

STI

as low as

^$257

Pittsburgh, US (PIT) - Santiago, DO (STI)

American Airlines

Sep 13

5:23pm

PIT

19h 4m

ORD

MIA

Sep 14

12:27pm

STI

as low as

^$257

Pittsburgh, US (PIT) - Santiago, DO (STI)

American Airlines

Sep 13

6:10am

PIT

6h 17m

MIA

Sep 13

12:27pm

STI

as low as

^$257

Pittsburgh, US (PIT) - Santiago, DO (STI)

JetBlue

Sep 13

7:00am

PIT

14h 27m

BOS

JFK

Sep 13

9:27pm

STI

as low as

^$259

Pittsburgh, US (PIT) - Santiago, DO (STI)

JetBlue

Sep 13

7:00am

PIT

11h 4m

BOS

JFK

Sep 13

6:04pm

STI

as low as

^$259

Pittsburgh, US (PIT) - Santiago, DO (STI)

United Airlines

Sep 13

8:46am

PIT

15h

ORD

EWR

Sep 13

11:46pm

STI

as low as

^$264

Pittsburgh, US (PIT) - Santiago, DO (STI)

United Airlines

Sep 13

6:15am

PIT

8h 57m

IAD

EWR

Sep 13

3:12pm

STI

as low as

^$264

Pittsburgh, US (PIT) - Santiago, DO (STI)

United Airlines

Sep 13

6:10am

PIT

17h 36m

IAH

EWR

Sep 13

11:46pm

STI

as low as

^$264

Pittsburgh, US (PIT) - Santiago, DO (STI)

United Airlines

Sep 13

8:10pm

PIT

16h 47m

IAD

EWR

Sep 14

12:57pm

STI

as low as

^$264

Pittsburgh, US (PIT) - Santiago, DO (STI)

American Airlines

Sep 13

10:03am

PIT

26h 24m

PHL

MIA

Sep 14

12:27pm

STI

as low as

^$287

Frequently Asked Questions

Are there convenient layover flights from Pittsburgh to Santiago?

Yes, there are convenient layover flights. JetBlue offers a 1 stop flight for $448 with a layover in New York. American Airlines provides a 1 stop flight for $538, with a layover in Miami. United Airlines has a 1 stop flight for $553, with a layover in Newark.

What are the most convenient layover airports for the flight?

The most convenient layover airports for your flight are New York John F Kennedy Airport, Miami International Airport, Newark Liberty Airport, Charlotte Douglas International Airport, and Chicago O'Hare Airport.

What are the cheapest and fastest flight options from Pittsburgh to Santiago?

The cheapest flight is with JetBlue for $448, taking 8 hours 20 minutes. The fastest flight is with American Airlines for $538, taking 6 hours 17 minutes.

What are all possible destination arrival airports?

The possible destination arrival airport is Cibao International Airport. Layover airports include New York John F Kennedy Airport, Miami International Airport, General Edward Lawrence Logan International Airport, Charlotte Douglas International Airport, Chicago O Hare Airport, and Newark Liberty Airport.

What is the time difference between Pittsburgh and Santiago?

The time difference between Pittsburgh and Santiago is typically 1 hour, with Santiago being ahead. Please verify current local times as daylight saving changes may apply.

Is there a direct flight from origin to destination?

There is no direct flight from Pittsburgh to Santiago. The available flights include 1 stop with JetBlue at $448 and American Airlines at $538. There are also 2 stops flights available. Please let me know if you need more information.

Flights to Santiago

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Call now!

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Flight Deals from Pittsburgh to Santiago from $212

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights from Pittsburgh to Santiago

Frequently Asked Questions

Flights to Santiago