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Flight Deals from Portland to Mayagueez from $433

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Stops

  • Up to 2 stops
    $906

Airlines

  • JetBlue
    $906
  • United Airlines
    $1153

Cabin Class

  • Economy
    $906

Departure Airports

  • Portland International Airport
    $906

Arrival Airports

  • Eugenio Maria De Hostos Airport
    $906

Layover Airports

  • Chicago O Hare Airport
    $1153
  • Denver International Airport
    $1423
  • General Edward Lawrence Logan International Airport
    $906
  • George Bush Intercontinental Houston Airport
    $1315
  • Luis Munoz Marin International Airport
    $906
  • Newark Liberty Airport
    $1315
  • Washington Dulles Airport
    $1201

Best Price. GUARANTEED.

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On average save $240 per traveler
JetBlue Logo
JetBlue

08/01/25

PDX
16h 2m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
15h 39m
SJU
BOS

08/08/25

PDX
$906
JetBlue Logo
JetBlue

08/01/25

PDX
16h 2m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
17h 40m
SJU
BOS

08/08/25

PDX
$906
JetBlue Logo
JetBlue

08/01/25

PDX
16h 2m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
35h 15m
SJU
BOS

08/09/25

PDX
$906
JetBlue Logo
JetBlue

08/01/25

PDX
16h 2m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
32h 15m
SJU
BOS

08/09/25

PDX
$906
JetBlue Logo
JetBlue

08/01/25

PDX
13h 47m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
17h 40m
SJU
BOS

08/08/25

PDX
$966
JetBlue Logo
JetBlue

08/01/25

PDX
13h 47m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
35h 15m
SJU
BOS

08/09/25

PDX
$966
JetBlue Logo
JetBlue

08/01/25

PDX
13h 47m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
32h 15m
SJU
BOS

08/09/25

PDX
$966
JetBlue Logo
JetBlue

08/01/25

PDX
13h 47m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
15h 39m
SJU
BOS

08/08/25

PDX
$966
United Airlines Logo
United Airlines

08/01/25

PDX
13h 28m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
22h 42m
SJU
ORD

08/09/25

PDX
$1153
United Airlines Logo
United Airlines

08/01/25

PDX
13h 28m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
28h 14m
SJU
ORD

08/09/25

PDX
$1168
United Airlines Logo
United Airlines

08/01/25

PDX
13h 28m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
24h 43m
SJU
ORD

08/09/25

PDX
$1168
United Airlines Logo
United Airlines

08/01/25

PDX
13h 28m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
32h 52m
SJU
IAD

08/09/25

PDX
$1201
United Airlines Logo
United Airlines

08/01/25

PDX
13h 28m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
31h 45m
SJU
ORD

08/09/25

PDX
$1303
United Airlines Logo
United Airlines

08/01/25

PDX
13h 28m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
21h 47m
SJU
EWR

08/09/25

PDX
$1315
United Airlines Logo
United Airlines

08/01/25

PDX
13h 28m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
24h 56m
SJU
IAH

08/09/25

PDX
$1315
United Airlines Logo
United Airlines

08/01/25

PDX
13h 28m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
32h 19m
SJU
IAH

08/09/25

PDX
$1320
United Airlines Logo
United Airlines

08/01/25

PDX
13h 28m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
33h 35m
SJU
EWR

08/09/25

PDX
$1352
United Airlines Logo
United Airlines

08/01/25

PDX
32h 27m
DEN
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
22h 42m
SJU
ORD

08/09/25

PDX
$1423
United Airlines Logo
United Airlines

08/01/25

PDX
32h 27m
DEN
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
24h 43m
SJU
ORD

08/09/25

PDX
$1438
United Airlines Logo
United Airlines

08/01/25

PDX
32h 27m
DEN
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
28h 14m
SJU
ORD

08/09/25

PDX
$1438
United Airlines Logo
United Airlines

08/01/25

PDX
30h 23m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
22h 42m
SJU
ORD

08/09/25

PDX
$1453
United Airlines Logo
United Airlines

08/01/25

PDX
24h 33m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
22h 42m
SJU
ORD

08/09/25

PDX
$1453
United Airlines Logo
United Airlines

08/01/25

PDX
24h 33m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
28h 14m
SJU
ORD

08/09/25

PDX
$1468
United Airlines Logo
United Airlines

08/01/25

PDX
30h 23m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
24h 43m
SJU
ORD

08/09/25

PDX
$1468
United Airlines Logo
United Airlines

08/01/25

PDX
24h 33m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
24h 43m
SJU
ORD

08/09/25

PDX
$1468
United Airlines Logo
United Airlines

08/01/25

PDX
27h 28m
EWR
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
22h 42m
SJU
ORD

08/09/25

PDX
$1559
United Airlines Logo
United Airlines

08/01/25

PDX
23h 50m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
22h 42m
SJU
ORD

08/09/25

PDX
$1654
United Airlines Logo
United Airlines

08/01/25

PDX
24h 33m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
21h 47m
SJU
EWR

08/09/25

PDX
$1655

Top Deals on flights from Portland to Mayagueez

Portland, US (PDX) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 1

PDX
16h 2m
BOS
SJU

Aug 2

MAZ

as low as

$433

Portland, US (PDX) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 1

PDX
13h 47m
BOS
SJU

Aug 2

MAZ

as low as

$493

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
13h 28m
ORD
SJU

Aug 2

MAZ

as low as

$562

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
14h 32m
ORD
SJU

Aug 2

MAZ

as low as

$562

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
14h 37m
EWR
SJU

Aug 2

MAZ

as low as

$562

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
14h 7m
IAD
SJU

Aug 2

MAZ

as low as

$642

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
23h 15m
ORD
SJU

Aug 2

MAZ

as low as

$746

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
27h 28m
EWR
SJU

Aug 2

MAZ

as low as

$776

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
32h 27m
DEN
SJU

Aug 2

MAZ

as low as

$798

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
30h 27m
ORD
SJU

Aug 2

MAZ

as low as

$806

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
24h 33m
IAH
SJU

Aug 2

MAZ

as low as

$862

Portland, US (PDX) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

PDX
30h 23m
IAH
SJU

Aug 2

MAZ

as low as

$862

Frequently Asked Questions

Are there convenient layover flights from Portland to Mayagueez?
Yes, there are convenient 2 stops flights from Portland to Mayagueez. JetBlue offers a flight for $906 with layovers at General Edward Lawrence Logan International Airport and Luis Munoz Marin International Airport. United Airlines offers a faster option at $1153 with layovers at Chicago O Hare Airport and Luis Munoz Marin International Airport.
What are the most convenient layover airports for my flight?
For your flight from Portland to Mayagueez, the most convenient layover airports are General Edward Lawrence Logan International Airport, Chicago O'Hare Airport, and Luis Munoz Marin International Airport.
What is the cheapest and fastest flight from Portland to Mayagueez?
The cheapest flight is with JetBlue at $906 with a total travel time of 16 hours 2 minutes. The fastest flight is with United Airlines at $1153 and takes 13 hours 28 minutes.
What are all possible destination arrival airports?
The possible destination arrival airport is Eugenio Maria De Hostos Airport. Layover airports include General Edward Lawrence Logan International Airport, Luis Munoz Marin International Airport, and Chicago O'Hare Airport.
What is the time difference between destination and arrival?
The time difference between Portland and Mayagueez is typically 4 hours, with Mayagueez being 4 hours ahead of Portland.
Is there a direct flight from Portland to Mayagueez?
There is no direct flight from Portland to Mayagueez. The cheapest option is a 2-stop flight with JetBlue for $906, and the fastest 2-stop flight is with United Airlines for $1153.
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