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Flight Deals from Medellin to Detroit from $394

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Bundle + Save

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Up to 1 stop
    $684
  • Up to 2 stops
    $688

Airlines

  • American Airlines
    $831
  • COPA Airlines
    $949
  • United Airlines
    $684

Cabin Class

  • Economy
    $684

Departure Airports

  • Jose Maria Córdova International Airport
    $684

Arrival Airports

  • Detroit Metropolitan Airport
    $684

Layover Airports

  • Charlotte Douglas International Airport
    $831
  • Chicago O Hare Airport
    $688
  • Dallas Fort Worth International Airport
    $831
  • George Bush Intercontinental Houston Airport
    $684
  • Miami International Airport
    $831
  • New York LaGuardia Airport
    $831
  • Philadelphia International Airport
    $831
  • Reagan Washington National Airport
    $831
  • Tocumen International Airport
    $949

Best Price. GUARANTEED.

Exclusively for Priceline Members
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We'll refund the difference if you find a lower price.

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BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
United Airlines Logo
United Airlines

07/25/25

MDE
13h 14m
IAH

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
13h 50m
IAH

08/01/25

MDE
$684
United Airlines Logo
United Airlines

07/25/25

MDE
13h 12m
IAH
ORD

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
13h 50m
IAH

08/01/25

MDE
$688
United Airlines Logo
United Airlines

07/25/25

MDE
13h 14m
IAH

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
16h 10m
ORD
IAH

08/01/25

MDE
$688
United Airlines Logo
United Airlines

07/25/25

MDE
13h 14m
IAH

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
22h 28m
ORD
IAH

08/02/25

MDE
$688
United Airlines Logo
United Airlines

07/25/25

MDE
13h 12m
IAH
ORD

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
16h 10m
ORD
IAH

08/01/25

MDE
$688
United Airlines Logo
United Airlines

07/25/25

MDE
13h 12m
IAH
ORD

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
22h 28m
ORD
IAH

08/02/25

MDE
$688
United Airlines Logo
United Airlines

07/25/25

MDE
13h 14m
IAH

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
21h 22m
IAH

08/02/25

MDE
$695
United Airlines Logo
United Airlines

07/25/25

MDE
22h 44m
IAH

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
13h 50m
IAH

08/01/25

MDE
$695
United Airlines Logo
United Airlines

07/25/25

MDE
12h 15m
IAH

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
13h 50m
IAH

08/01/25

MDE
$737
United Airlines Logo
United Airlines

07/25/25

MDE
14h 48m
IAH

07/25/25

DTW
United Airlines Logo
United Airlines

08/01/25

DTW
13h 50m
IAH

08/01/25

MDE
$737
American Airlines Logo
American Airlines

07/25/25

MDE
16h 55m
MIA
DFW

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
13h 43m
LGA
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
13h 32m
MIA
PHL

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
11h 5m
CLT
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
11h 44m
MIA
CLT

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
11h 36m
DCA
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
11h 44m
MIA
CLT

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
13h 9m
CLT
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
16h 55m
MIA
DFW

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
11h 36m
DCA
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
10h 44m
MIA
PHL

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
14h
CLT
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
13h 32m
MIA
PHL

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
13h 43m
LGA
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
10h 44m
MIA
PHL

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
11h 36m
DCA
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
13h 33m
MIA
CLT

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
11h 36m
DCA
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
10h 44m
MIA
PHL

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
13h 43m
LGA
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
16h 55m
MIA
DFW

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
11h 5m
CLT
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
16h 59m
MIA
CLT

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
14h
CLT
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
16h 55m
MIA
DFW

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
14h
CLT
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
11h 44m
MIA
CLT

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
13h 43m
LGA
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
16h 55m
MIA
DFW

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
13h 9m
CLT
MIA

08/01/25

MDE
$831
American Airlines Logo
American Airlines

07/25/25

MDE
13h 32m
MIA
PHL

07/25/25

DTW
American Airlines Logo
American Airlines

08/01/25

DTW
11h 36m
DCA
MIA

08/01/25

MDE
$831
COPA Airlines Logo
COPA Airlines

07/25/25

MDE
15h 58m
PTY
ORD

07/25/25

DTW
COPA Airlines Logo
COPA Airlines

08/01/25

DTW
33h 10m
ORD
PTY

08/02/25

MDE
$949
COPA Airlines Logo
COPA Airlines

07/25/25

MDE
28h 16m
PTY
ORD

07/26/25

DTW
COPA Airlines Logo
COPA Airlines

08/01/25

DTW
33h 10m
ORD
PTY

08/02/25

MDE
$1013
COPA Airlines Logo
COPA Airlines

07/25/25

MDE
27h 15m
PTY
ORD

07/26/25

DTW
COPA Airlines Logo
COPA Airlines

08/01/25

DTW
33h 10m
ORD
PTY

08/02/25

MDE
$1013
COPA Airlines Logo
COPA Airlines

07/25/25

MDE
15h 58m
PTY
ORD

07/25/25

DTW
COPA Airlines Logo
COPA Airlines

08/01/25

DTW
24h 27m
ORD
PTY

08/02/25

MDE
$1221

Top Deals on flights from Medellin to Detroit

Medellin, CO (MDE) - Detroit, US (DTT)

COPA Airlines Logo
COPA Airlines

Jul 25

MDE
28h 35m
PTY
ORD

Jul 26

DTW

as low as

$394

Medellin, CO (MDE) - Detroit, US (DTT)

COPA Airlines Logo
COPA Airlines

Jul 25

MDE
29h 36m
PTY
ORD

Jul 26

DTW

as low as

$394

Medellin, CO (MDE) - Detroit, US (DTT)

COPA Airlines Logo
COPA Airlines

Jul 25

MDE
32h 20m
PTY
ORD

Jul 26

DTW

as low as

$394

Medellin, CO (MDE) - Detroit, US (DTT)

COPA Airlines Logo
COPA Airlines

Jul 25

MDE
34h 19m
PTY
ORD

Jul 26

DTW

as low as

$394

Medellin, CO (MDE) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 25

MDE
14h 48m
IAH

Jul 25

DTW

as low as

$498

Medellin, CO (MDE) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 25

MDE
13h 14m
IAH

Jul 25

DTW

as low as

$498

Medellin, CO (MDE) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 25

MDE
12h 15m
IAH

Jul 25

DTW

as low as

$498

Medellin, CO (MDE) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 25

MDE
13h 12m
IAH
ORD

Jul 25

DTW

as low as

$502

Medellin, CO (MDE) - Detroit, US (DTT)

United Airlines Logo
United Airlines

Jul 25

MDE
22h 44m
IAH

Jul 25

DTW

as low as

$511

Medellin, CO (MDE) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Jul 25

MDE
16h 15m
MIA

Jul 25

DTW

as low as

$588

Medellin, CO (MDE) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Jul 25

MDE
10h 44m
MIA
PHL

Jul 25

DTW

as low as

$593

Medellin, CO (MDE) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Jul 25

MDE
11h 44m
MIA
CLT

Jul 25

DTW

as low as

$593

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