
Flight Deals from Lyon to San Francisco from $498
Top flight deals from leading airlines:







... and +100s more
Save up to 50% on select flights with Priceline
Save an average of $240 per person when bundling your flight and hotel together with Priceline
If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference
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Stops
- Up to 1 stop$518
- Up to 2 stops$734
Airlines
- Austrian Airlines$814
- British Airways$729
- Brussels Airlines$1046
- IBERIA$893
- Lufthansa$730
- TAP Portugal$518
- Turkish Airlines$1009
Cabin Class
- Economy$518
Departure Airports
- Lyon Saint-Exupéry Airport$518
Arrival Airports
- San Francisco International Airport$518
Layover Airports
- Adolfo Suárez Madrid–Barajas Airport$919
- Barcelona International Airport$894
- Brussels Airport$1046
- Chicago O Hare Airport$735
- Dallas Fort Worth International Airport$899
- Frankfurt am Main Airport$730
- Humberto Delgado Airport (Lisbon Portela Airport)$518
- Istanbul Airport$1009
- London Heathrow Airport$729
- Los Angeles International Airport$734
- Montreal Trudeau Airport$735
- Munich Airport$730
- New York John F Kennedy Airport$741
- Newark Liberty Airport$737
- Toronto Pearson Airport$804
- Vienna International Airport$814
- Washington Dulles Airport$770
Best Price. GUARANTEED.
Exclusively for Priceline Members
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Top Deals on flights from Lyon to San Francisco
Lyon, FR (LYS) - San Francisco, US (SFO)

Oct 1
Oct 2
as low as
$498
Lyon, FR (LYS) - San Francisco, US (SFO)

Sep 10
Sep 11
as low as
$606
Lyon, FR (LYS) - San Francisco, US (SFO)

Sep 12
Sep 12
as low as
$741
Lyon, FR (LYS) - San Francisco, US (SFO)

Sep 11
Sep 11
as low as
$757
Lyon, FR (LYS) - San Francisco, US (SFO)

Jan 3
Jan 4
as low as
$868
Lyon, FR (LYS) - San Francisco, US (SFO)

Sep 11
Sep 11
as low as
$900
Lyon, FR (LYS) - San Francisco, US (SFO)

Sep 11
Sep 11
as low as
$969
Lyon, FR (LYS) - San Francisco, US (SFO)

Sep 11
Sep 12
as low as
$1010
Lyon, FR (LYS) - San Francisco, US (SFO)

Sep 10
Sep 11
as low as
$1025
Lyon, FR (LYS) - San Francisco, US (SFO)

Oct 1
Oct 1
as low as
$1026
Lyon, FR (LYS) - San Francisco, US (SFO)

Sep 11
Sep 12
as low as
$1026
Lyon, FR (LYS) - San Francisco, US (SFO)

Sep 11
Sep 11
as low as
$1149
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