$756 Flight Deals from Johannesburg to San Francisco

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Stops

Up to 1 stop
$1011
Up to 2 stops
$978

Airlines

Air France
$1373
American Airlines
$1282
British Airways
$1169
Brussels Airlines
$1004
Cathay Pacific
$1485
Delta Air Lines
$1447
Emirates
$1522
Kenya Airways
$1328
KLM
$1375
Lufthansa
$1002
Qatar Airways
$1482
Singapore Airlines
$1542
SWISS
$978
Turkish Airlines
$1036
United Airlines
$1037
Virgin Atlantic
$1011

Cabin Class

Economy
$978

Departure Airports

OR Tambo International Airport
$978

Arrival Airports

San Francisco International Airport
$978

Layover Airports

Amsterdam Airport Schiphol
$1852
Cape Town International Airport
$1014
Dubai International Airport
$1522
Frankfurt am Main Airport
$1004
Hamad International Airport
$1482
Hong Kong International Airport
$1485
Istanbul Airport
$1036
Jomo Kenyatta International Airport
$1328
London Heathrow Airport
$1011
Los Angeles International Airport
$1047
Montreal Trudeau Airport
$1893
Munich Airport
$978
New York John F Kennedy Airport
$1328
Paris Charles de Gaulle Airport
$1373
Singapore Changi Airport
$1542
Vancouver International Airport
$978
Zürich Airport
$978

Best Price. GUARANTEED.

Exclusively for Priceline Members
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BUNDLE & SAVE

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On average save $240 per traveler

SWISS

11/06/25

8:15pm

JNB

20h 15m

ZRH

11/07/25

4:30pm

SFO

SWISS

11/22/25

6:53pm

SFO

60h 12m

YVR

MUC

11/25/25

7:05am

JNB

^$978

Lufthansa

11/06/25

10:10am

JNB

33h 25m

MUC

11/07/25

7:35pm

SFO

Lufthansa

11/22/25

6:53pm

SFO

60h 12m

YVR

MUC

11/25/25

7:05am

JNB

^$1002

Brussels Airlines

11/06/25

7:45pm

JNB

16h 55m

FRA

11/07/25

12:40pm

SFO

Brussels Airlines

11/22/25

6:53pm

SFO

60h 12m

YVR

MUC

11/25/25

7:05am

JNB

^$1004

Virgin Atlantic

11/20/25

9:30pm

JNB

17h 10m

LHR

11/21/25

2:40pm

SFO

Virgin Atlantic

11/26/25

4:30pm

SFO

40h 10m

LHR

11/28/25

8:40am

JNB

^$1011

Lufthansa

11/06/25

12:20pm

JNB

24h 20m

CPT

FRA

11/07/25

12:40pm

SFO

Lufthansa

11/22/25

6:53pm

SFO

60h 12m

YVR

MUC

11/25/25

7:05am

JNB

^$1014

Virgin Atlantic

11/06/25

9:30pm

JNB

17h 10m

LHR

11/07/25

2:40pm

SFO

Virgin Atlantic

11/22/25

4:30pm

SFO

40h 10m

LHR

11/24/25

8:40am

JNB

^$1021

Turkish Airlines

11/20/25

7:10pm

JNB

21h 35m

IST

11/21/25

4:45pm

SFO

Turkish Airlines

11/26/25

6:50pm

SFO

40h

IST

11/28/25

10:50am

JNB

^$1036

United Airlines

11/06/25

7:45pm

JNB

24h 25m

FRA

11/07/25

8:10pm

SFO

United Airlines

11/22/25

9:40pm

SFO

59h 50m

MUC

FRA

11/25/25

9:30am

JNB

^$1037

United Airlines

11/06/25

7:45pm

JNB

21h 53m

FRA

LAX

11/07/25

5:38pm

SFO

United Airlines

11/22/25

9:40pm

SFO

59h 50m

MUC

FRA

11/25/25

9:30am

JNB

^$1047

British Airways

11/06/25

10:00pm

JNB

17h

LHR

11/07/25

3:00pm

SFO

British Airways

11/22/25

8:40pm

SFO

34h 55m

LHR

11/24/25

7:35am

JNB

^$1169

SWISS

11/06/25

8:15pm

JNB

17h 5m

ZRH

LHR

11/07/25

1:20pm

SFO

SWISS

11/22/25

5:25pm

SFO

41h 5m

LHR

ZRH

11/24/25

10:30am

JNB

^$1189

British Airways

11/20/25

10:00pm

JNB

17h

LHR

11/21/25

3:00pm

SFO

British Airways

11/26/25

11:12am

SFO

47h 13m

LAX

LHR

11/28/25

10:25am

JNB

^$1208

Brussels Airlines

11/06/25

7:45pm

JNB

16h 55m

FRA

11/07/25

12:40pm

SFO

Brussels Airlines

11/22/25

7:25pm

SFO

39h 5m

ZRH

11/24/25

10:30am

JNB

^$1229

American Airlines

11/06/25

10:00pm

JNB

20h 45m

LHR

11/07/25

6:45pm

SFO

American Airlines

11/22/25

8:40pm

SFO

37h 45m

LHR

11/24/25

10:25am

JNB

^$1282

Kenya Airways

11/06/25

5:00pm

JNB

20h 8m

NBO

JFK

11/07/25

1:08pm

SFO

Kenya Airways

11/22/25

1:29pm

SFO

50h 21m

JFK

NBO

11/24/25

3:50pm

JNB

^$1328

Turkish Airlines

11/06/25

7:10pm

JNB

21h 35m

IST

11/07/25

4:45pm

SFO

Turkish Airlines

11/22/25

1:10pm

SFO

45h 40m

IST

11/24/25

10:50am

JNB

^$1334

Air France

11/06/25

7:40pm

JNB

17h 55m

CDG

11/07/25

1:35pm

SFO

Air France

11/22/25

3:50pm

SFO

44h

CDG

11/24/25

11:50am

JNB

^$1373

KLM

11/06/25

7:40pm

JNB

17h 55m

CDG

11/07/25

1:35pm

SFO

KLM

11/22/25

3:50pm

SFO

44h

CDG

11/24/25

11:50am

JNB

^$1375

Delta Air Lines

11/20/25

9:30pm

JNB

17h 10m

LHR

11/21/25

2:40pm

SFO

Delta Air Lines

11/26/25

6:58pm

SFO

64h 52m

LAX

CDG

11/29/25

11:50am

JNB

^$1447

Qatar Airways

11/20/25

1:45pm

JNB

22h 55m

DOH

11/21/25

12:40pm

SFO

Qatar Airways

11/26/25

3:00pm

SFO

41h 40m

DOH

11/28/25

8:40am

JNB

^$1482

Cathay Pacific

11/06/25

11:05am

JNB

22h 40m

HKG

11/07/25

9:45am

SFO

Cathay Pacific

11/22/25

11:25am

SFO

44h 15m

HKG

11/24/25

7:40am

JNB

^$1485

Qatar Airways

11/06/25

1:45pm

JNB

22h 55m

DOH

11/07/25

12:40pm

SFO

Qatar Airways

11/22/25

3:00pm

SFO

48h 35m

DOH

11/24/25

3:35pm

JNB

^$1500

Emirates

11/20/25

10:25am

JNB

26h 25m

DXB

11/21/25

12:50pm

SFO

Emirates

11/26/25

3:40pm

SFO

42h 45m

DXB

11/28/25

10:25am

JNB

^$1522

Singapore Airlines

11/06/25

1:40pm

JNB

18h 10m

SIN

11/07/25

7:50am

SFO

Singapore Airlines

11/22/25

9:40am

SFO

44h 30m

SIN

11/24/25

6:10am

JNB

^$1542

Delta Air Lines

11/20/25

9:30pm

JNB

17h 10m

LHR

11/21/25

2:40pm

SFO

Delta Air Lines

11/26/25

4:30pm

SFO

40h 10m

LHR

11/28/25

8:40am

JNB

^$1551

Emirates

11/06/25

6:50pm

JNB

18h

DXB

11/07/25

12:50pm

SFO

Emirates

11/22/25

3:40pm

SFO

37h 55m

DXB

11/24/25

5:35am

JNB

^$1603

Kenya Airways

11/06/25

5:00pm

JNB

21h 27m

NBO

JFK

11/07/25

2:27pm

SFO

Kenya Airways

11/22/25

2:20pm

SFO

49h 30m

JFK

NBO

11/24/25

3:50pm

JNB

^$1625

Air France

11/20/25

7:40pm

JNB

16h 10m

CDG

AMS

11/21/25

11:50am

SFO

Air France

11/26/25

4:30pm

SFO

40h 10m

LHR

11/28/25

8:40am

JNB

^$1852

KLM

11/20/25

7:40pm

JNB

17h 55m

CDG

11/21/25

1:35pm

SFO

KLM

11/26/25

8:55am

SFO

50h 55m

LAX

CDG

11/28/25

11:50am

JNB

^$1883

Brussels Airlines

11/06/25

7:45pm

JNB

16h 55m

FRA

11/07/25

12:40pm

SFO

Brussels Airlines

11/22/25

8:25am

SFO

49h 5m

YUL

FRA

11/24/25

9:30am

JNB

^$1893

Top Deals on flights from Johannesburg to San Francisco

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Turkish Airlines

Oct 2

5:50pm

JNB

16h 45m

IST

Oct 3

10:35am

SFO

as low as

^$756

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Jan 18

8:20pm

JNB

41h 19m

DOH

JFK

Jan 20

1:39pm

SFO

as low as

^$776

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Etihad Airways

Sep 8

9:50am

JNB

35h 53m

AUH

BOS

Sep 9

9:43pm

SFO

as low as

^$839

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Singapore Airlines

Sep 8

7:50pm

JNB

37h 50m

SIN

Sep 10

9:40am

SFO

as low as

^$841

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Qatar Airways

Sep 24

1:55pm

JNB

23h 40m

DOH

Sep 25

1:35pm

SFO

as low as

^$846

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Kenya Airways

Oct 2

5:00pm

JNB

28h 3m

NBO

JFK

Oct 3

9:03pm

SFO

as low as

^$890

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Cathay Pacific

Jan 18

11:05am

JNB

22h 25m

HKG

Jan 19

9:30am

SFO

as low as

^$917

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Qatar Airways

Sep 8

1:55pm

JNB

29h 7m

DOH

LAX

Sep 9

7:02pm

SFO

as low as

^$922

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Emirates

Oct 2

7:10pm

JNB

18h 50m

DXB

Oct 3

2:00pm

SFO

as low as

^$936

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Delta Air Lines

Sep 30

8:30pm

JNB

17h 45m

LHR

Oct 1

2:15pm

SFO

as low as

^$944

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Virgin Atlantic

Sep 30

8:30pm

JNB

17h 45m

LHR

Oct 1

2:15pm

SFO

as low as

^$964

Johannesburg, ZA (JNB) - San Francisco, US (SFO)

Delta Air Lines

Sep 30

11:15pm

JNB

20h 33m

AMS

LAX

Oct 1

7:48pm

SFO

as low as

^$965

Frequently Asked Questions

Is there a direct flight from Johannesburg to San Francisco?

There is no direct flight from Johannesburg to San Francisco. The options available include one-stop flights with SWISS for $978, Lufthansa for $1002, Brussels Airlines for $1004, Virgin Atlantic for $1011, and Turkish Airlines for $1036.

Are there convenient layover flights from Johannesburg to San Francisco?

Yes, convenient 1 stop flights from Johannesburg to San Francisco include SWISS at $978, Lufthansa at $1002, Brussels Airlines at $1004, Virgin Atlantic at $1011, and Turkish Airlines at $1036. Additionally, 2 stop flights are available with Lufthansa at $1014, United Airlines at $1047, SWISS at $1189, Kenya Airways at $1328, and British Airways at $1331.

What are the most convenient layover airports for my flight?

The most convenient layover airports for your flight are Zürich Airport (SWISS), Munich Airport (Lufthansa), Frankfurt am Main Airport (Brussels Airlines), London Heathrow Airport (Virgin Atlantic), and Istanbul Airport (Turkish Airlines).

What is the cheapest and fastest flight from Johannesburg to San Francisco?

The cheapest flight is with SWISS for $978, 20h 15m. The fastest is with Air France for $1852, 16h 10m with layovers at Paris and Amsterdam.

What are all possible destination arrival airports?

Possible destination arrival airports include San Francisco International Airport, Zürich Airport, Munich Airport, Frankfurt am Main Airport, London Heathrow Airport, Istanbul Airport, Cape Town International Airport, Jomo Kenyatta International Airport, and Los Angeles International Airport.

What is the time difference between destination and arrival?

The time difference between Johannesburg and San Francisco is 10 hours, with Johannesburg ahead. Please consider this when planning your travel schedule.

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Flight Deals from Johannesburg to San Francisco from $756

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Arrival Airports

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Top Deals on flights from Johannesburg to San Francisco

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