
Flight Deals from Houston to Santiago from $137
Top flight deals from leading airlines:







... and +100s more
Save up to 50% on select flights with Priceline
Save an average of $240 per person when bundling your flight and hotel together with Priceline
If a VIP member finds a better price elsewhere, we'll refund up to 200% of the difference
We’re always here for you - reach us 24 hours a day, 7 days a week
Stops
- Up to 1 stop$310
- Up to 2 stops$611
Airlines
- American Airlines$611
- JetBlue$643
- Spirit Airlines$310
- United Airlines$621
Cabin Class
- Economy$310
Departure Airports
- George Bush Intercontinental Houston Airport$310
- William P Hobby Airport$611
Arrival Airports
- Cibao International Airport$310
Layover Airports
- Charlotte Douglas International Airport$611
- Dallas Fort Worth International Airport$611
- Fort Lauderdale Hollywood International Airport$310
- General Edward Lawrence Logan International Airport$643
- Miami International Airport$611
- New York John F Kennedy Airport$643
- Newark Liberty Airport$621
Best Price. GUARANTEED.
Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

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Top Deals on flights from Houston to Santiago
Houston, US (HOU) - Santiago, DO (STI)

Sep 11
Sep 12
as low as
$137
Houston, US (HOU) - Santiago, DO (STI)

Nov 12
Nov 12
as low as
$138
Houston, US (HOU) - Santiago, DO (STI)

Nov 12
Nov 13
as low as
$285
Houston, US (HOU) - Santiago, DO (STI)

Sep 11
Sep 12
as low as
$298
Houston, US (HOU) - Santiago, DO (STI)

Nov 12
Nov 13
as low as
$319
Houston, US (HOU) - Santiago, DO (STI)

Oct 3
Oct 4
as low as
$325
Houston, US (HOU) - Santiago, DO (STI)

Nov 15
Nov 16
as low as
$326
Houston, US (HOU) - Santiago, DO (STI)

Nov 15
Nov 16
as low as
$326
Houston, US (HOU) - Santiago, DO (STI)

Oct 3
Oct 4
as low as
$331
Houston, US (HOU) - Santiago, DO (STI)

Sep 11
Sep 11
as low as
$349
Houston, US (HOU) - Santiago, DO (STI)

Sep 11
Sep 12
as low as
$349
Houston, US (HOU) - Santiago, DO (STI)

Sep 11
Sep 11
as low as
$357
Frequently Asked Questions
Flights to Santiago
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