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Flight Deals from Fort Myers to Mayagueez from $325

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Bundle + Save

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Up to 2 stops
    $724

Airlines

  • JetBlue
    $724
  • United Airlines
    $1807

Cabin Class

  • Economy
    $724

Departure Airports

  • Southwest Florida International Airport
    $724

Arrival Airports

  • Eugenio Maria De Hostos Airport
    $724

Layover Airports

  • Chicago O Hare Airport
    $1815
  • General Edward Lawrence Logan International Airport
    $724
  • Luis Munoz Marin International Airport
    $724
  • New York John F Kennedy Airport
    $724
  • Newark Liberty Airport
    $1807

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Exclusively for Priceline Members
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BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
JetBlue Logo
JetBlue

09/01/25

RSW
10h 27m
BOS
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
24h 44m
SJU
JFK

09/09/25

RSW
$724
JetBlue Logo
JetBlue

09/01/25

RSW
12h 42m
BOS
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
24h 44m
SJU
JFK

09/09/25

RSW
$724
JetBlue Logo
JetBlue

09/01/25

RSW
12h 42m
BOS
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
23h 5m
SJU
BOS

09/09/25

RSW
$731
JetBlue Logo
JetBlue

09/01/25

RSW
10h 27m
BOS
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
23h 5m
SJU
BOS

09/09/25

RSW
$731
JetBlue Logo
JetBlue

09/01/25

RSW
12h 42m
BOS
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
13h 42m
SJU
BOS

09/08/25

RSW
$799
JetBlue Logo
JetBlue

09/01/25

RSW
12h 42m
BOS
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
15h 43m
SJU
BOS

09/08/25

RSW
$799
JetBlue Logo
JetBlue

09/01/25

RSW
10h 27m
BOS
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
13h 42m
SJU
BOS

09/08/25

RSW
$799
JetBlue Logo
JetBlue

09/01/25

RSW
10h 27m
BOS
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
15h 43m
SJU
BOS

09/08/25

RSW
$799
JetBlue Logo
JetBlue

09/01/25

RSW
12h 42m
JFK
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
24h 44m
SJU
JFK

09/09/25

RSW
$901
JetBlue Logo
JetBlue

09/01/25

RSW
12h 42m
JFK
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
23h 5m
SJU
BOS

09/09/25

RSW
$908
JetBlue Logo
JetBlue

09/01/25

RSW
20h 7m
JFK
SJU

09/02/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
15h 43m
SJU
BOS

09/08/25

RSW
$923
JetBlue Logo
JetBlue

09/01/25

RSW
20h 7m
JFK
SJU

09/02/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
13h 42m
SJU
BOS

09/08/25

RSW
$923
JetBlue Logo
JetBlue

09/01/25

RSW
12h 42m
JFK
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
13h 42m
SJU
BOS

09/08/25

RSW
$976
JetBlue Logo
JetBlue

09/01/25

RSW
12h 42m
JFK
SJU

09/01/25

MAZ
JetBlue Logo
JetBlue

09/08/25

MAZ
15h 43m
SJU
BOS

09/08/25

RSW
$976
United Airlines Logo
United Airlines

09/01/25

RSW
21h 4m
EWR
SJU

09/02/25

MAZ
United Airlines Logo
United Airlines

09/08/25

MAZ
21h 42m
SJU
EWR

09/09/25

RSW
$1807
United Airlines Logo
United Airlines

09/01/25

RSW
21h 4m
EWR
SJU

09/02/25

MAZ
United Airlines Logo
United Airlines

09/08/25

MAZ
21h 56m
SJU
ORD

09/09/25

RSW
$1815
United Airlines Logo
United Airlines

09/01/25

RSW
21h 4m
EWR
SJU

09/02/25

MAZ
United Airlines Logo
United Airlines

09/08/25

MAZ
28h 38m
SJU
EWR

09/09/25

RSW
$1820
United Airlines Logo
United Airlines

09/01/25

RSW
21h 4m
EWR
SJU

09/02/25

MAZ
United Airlines Logo
United Airlines

09/08/25

MAZ
25h 21m
SJU
ORD

09/09/25

RSW
$1828
United Airlines Logo
United Airlines

09/01/25

RSW
21h 4m
EWR
SJU

09/02/25

MAZ
United Airlines Logo
United Airlines

09/08/25

MAZ
30h 55m
SJU
ORD

09/09/25

RSW
$1828
United Airlines Logo
United Airlines

09/01/25

RSW
28h 3m
EWR
SJU

09/02/25

MAZ
United Airlines Logo
United Airlines

09/08/25

MAZ
21h 42m
SJU
EWR

09/09/25

RSW
$1838
United Airlines Logo
United Airlines

09/01/25

RSW
28h 3m
EWR
SJU

09/02/25

MAZ
United Airlines Logo
United Airlines

09/08/25

MAZ
21h 56m
SJU
ORD

09/09/25

RSW
$1846
United Airlines Logo
United Airlines

09/01/25

RSW
33h 15m
EWR
SJU

09/02/25

MAZ
United Airlines Logo
United Airlines

09/08/25

MAZ
21h 56m
SJU
ORD

09/09/25

RSW
$1846

Top Deals on flights from Fort Myers to Mayagueez

Fort Myers, US (FMY) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Sep 2

RSW
20h 34m
JFK
SJU

Sep 3

MAZ

as low as

$325

Fort Myers, US (FMY) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Sep 2

RSW
12h 42m
BOS
SJU

Sep 2

MAZ

as low as

$338

Fort Myers, US (FMY) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Sep 2

RSW
12h 42m
JFK
SJU

Sep 2

MAZ

as low as

$349

Fort Myers, US (FMY) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Sep 2

RSW
20h 50m
BOS
SJU

Sep 3

MAZ

as low as

$394

Fort Myers, US (FMY) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Sep 2

RSW
21h 8m
EWR
SJU

Sep 3

MAZ

as low as

$928

Fort Myers, US (FMY) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Sep 2

RSW
28h
EWR
SJU

Sep 3

MAZ

as low as

$965

Frequently Asked Questions

Are there convenient layover flights from Fort Myers to Mayagueez?
Yes, there are convenient layover flights from Fort Myers to Mayagueez. JetBlue offers a 2-stop flight for $724, while United Airlines provides a 2-stop flight for $1807.
What are the most convenient layover airports for my flight?
For your flight from Fort Myers to Mayagueez, the most convenient layover airports are General Edward Lawrence Logan International Airport, Luis Munoz Marin International Airport, and Newark Liberty Airport.
What is the cheapest and fastest flight from Fort Myers to Mayagueez?
The cheapest and fastest flight is with JetBlue at $724, with 2 stops and layovers at General Edward Lawrence Logan International and Luis Munoz Marin airports. Fastest flight time is 10 hours 27 minutes.
What are all possible destination arrival airports?
The possible destination arrival airport is Eugenio Maria De Hostos Airport, with layover airports being General Edward Lawrence Logan International Airport, Luis Munoz Marin International Airport, and Newark Liberty Airport.
What is the time difference between destination and arrival?
The time difference between Fort Myers and Mayagueez is one hour, with Mayagueez being one hour ahead of Fort Myers.
Is there a direct flight from Fort Myers to Mayagueez?
There is no direct flight from Fort Myers to Mayagueez. The available flights require layovers, with JetBlue offering the cheapest option at a price of $724 and a total flight time of 12 hours 42 minutes.
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