$74 Flight Deals from Detroit to Santa Ana

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Price Drop Deals Near You

Santa Ana

55% Price Drop

Aug 14

DTW

3 days

Aug 17

SNA

$315

now only

^$141

Round Trip

Santa Ana

11% Price Drop

Jul 26

DTW

3 days

Jul 29

SNA

$315

now only

^$281

Round Trip

Stops

Nonstop
from $661
Up to 1 stop
$397
Up to 2 stops
$622

Airlines

Alaska Airlines
$622
American Airlines
$397
Delta Air Lines
$621
Hawaiian Airlines
$730
United Airlines
$506

Cabin Class

Economy
$397

Departure Airports

Detroit Metropolitan Airport
$397

Arrival Airports

John Wayne Airport-Orange County Airport
$397

Layover Airports

Charlotte Douglas International Airport
$606
Chicago O Hare Airport
$438
Dallas Fort Worth International Airport
$397
Denver International Airport
$506
George Bush Intercontinental Houston Airport
$566
Phoenix Sky Harbor International Airport
$397
Reagan Washington National Airport
$713
Salt Lake City International Airport
$621
San Francisco International Airport
$566
Seattle Tacoma International Airport
$622

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

American Airlines

11/13/25

5:02am

DTW

4h 33m

DFW

11/13/25

9:35am

SNA

American Airlines

11/19/25

6:47am

SNA

8h 38m

PHX

11/19/25

3:25pm

DTW

^$397

American Airlines

11/07/25

7:09am

DTW

5h 13m

ORD

11/07/25

12:22pm

SNA

American Airlines

11/16/25

12:10am

SNA

10h 13m

ORD

11/16/25

10:23am

DTW

^$438

United Airlines

11/16/25

4:15pm

DTW

6h 2m

ORD

11/16/25

10:17pm

SNA

United Airlines

12/04/25

5:10am

SNA

9h 42m

DEN

12/04/25

2:52pm

DTW

^$506

United Airlines

11/13/25

4:55pm

DTW

3h 58m

DEN

11/13/25

8:53pm

SNA

United Airlines

11/19/25

5:40am

SNA

9h 34m

DEN

11/19/25

3:14pm

DTW

^$506

United Airlines

11/20/25

6:00am

DTW

5h 44m

ORD

11/20/25

11:44am

SNA

United Airlines

11/28/25

1:00pm

SNA

9h 23m

DEN

11/28/25

10:23pm

DTW

^$566

United Airlines

11/19/25

8:15am

DTW

5h 17m

IAH

11/19/25

1:32pm

SNA

United Airlines

12/07/25

6:00am

SNA

12h 43m

SFO

12/07/25

6:43pm

DTW

^$566

American Airlines

11/12/25

7:09am

DTW

4h 30m

DFW

11/12/25

11:39am

SNA

American Airlines

11/14/25

11:51am

SNA

10h 15m

CLT

11/14/25

10:06pm

DTW

^$606

Delta Air Lines

11/12/25

8:30am

DTW

2h 9m

Direct

11/12/25

10:39am

SNA

Delta Air Lines

11/14/25

1:00pm

SNA

11h 3m

SLC

11/15/25

12:03am

DTW

^$621

Alaska Airlines

11/24/25

4:40pm

DTW

5h 50m

SEA

11/24/25

10:30pm

SNA

Alaska Airlines

12/02/25

6:00am

SNA

16h 49m

SEA

ORD

12/02/25

10:49pm

DTW

^$622

American Airlines

12/05/25

4:00pm

DTW

6h 6m

DFW

12/05/25

10:06pm

SNA

American Airlines

12/14/25

12:40pm

SNA

11h 35m

DFW

12/15/25

12:15am

DTW

^$637

Delta Air Lines

11/12/25

8:30am

DTW

2h 9m

Direct

11/12/25

10:39am

SNA

Delta Air Lines

11/14/25

2:45pm

SNA

7h 29m

Direct

11/14/25

10:14pm

DTW

^$661

United Airlines

11/26/25

4:55pm

DTW

5h 34m

DEN

11/26/25

10:29pm

SNA

United Airlines

11/29/25

12:25am

SNA

9h 20m

ORD

11/29/25

9:45am

DTW

^$666

United Airlines

11/25/25

7:15am

DTW

4h 29m

ORD

11/25/25

11:44am

SNA

United Airlines

11/29/25

6:00am

SNA

9h 28m

ORD

11/29/25

3:28pm

DTW

^$666

Alaska Airlines

11/24/25

4:40pm

DTW

5h 50m

SEA

11/24/25

10:30pm

SNA

Alaska Airlines

12/02/25

12:45pm

SNA

11h 7m

DCA

12/02/25

11:52pm

DTW

^$713

Hawaiian Airlines

11/27/25

4:40pm

DTW

5h 50m

SEA

11/27/25

10:30pm

SNA

Hawaiian Airlines

11/30/25

10:00am

SNA

29h 22m

SEA

12/01/25

3:22pm

DTW

^$730

American Airlines

11/26/25

6:27pm

DTW

3h 18m

PHX

11/26/25

9:45pm

SNA

American Airlines

11/29/25

12:10am

SNA

10h 13m

ORD

11/29/25

10:23am

DTW

^$742

Alaska Airlines

12/01/25

4:40pm

DTW

5h 50m

SEA

12/01/25

10:30pm

SNA

Alaska Airlines

12/07/25

6:55pm

SNA

15h 34m

SEA

ORD

12/08/25

10:29am

DTW

^$876

American Airlines

11/21/25

6:27pm

DTW

3h 18m

PHX

11/21/25

9:45pm

SNA

American Airlines

11/30/25

11:18pm

SNA

11h 27m

CLT

12/01/25

10:45am

DTW

^$882

Alaska Airlines

11/27/25

4:40pm

DTW

5h 50m

SEA

11/27/25

10:30pm

SNA

Alaska Airlines

11/30/25

5:00pm

SNA

17h 23m

SEA

ORD

12/01/25

10:23am

DTW

^$925

Alaska Airlines

12/01/25

4:40pm

DTW

5h 50m

SEA

12/01/25

10:30pm

SNA

Alaska Airlines

12/07/25

12:45pm

SNA

10h 59m

DCA

12/07/25

11:44pm

DTW

^$1017

Alaska Airlines

11/12/25

7:09am

DTW

5h 13m

ORD

11/12/25

12:22pm

SNA

Alaska Airlines

11/14/25

12:59pm

SNA

11h 4m

SLC

11/15/25

12:03am

DTW

^$9784

Alaska Airlines

11/12/25

7:09am

DTW

5h 13m

ORD

11/12/25

12:22pm

SNA

Alaska Airlines

11/14/25

6:00am

SNA

16h 49m

SEA

ORD

11/14/25

10:49pm

DTW

^$10712

Top Deals on flights from Detroit to Santa Ana

Detroit, US (DTT) - Santa Ana, US (SNA)

Aug 14

9:40am

DTW

1h 49m

Direct

Aug 14

11:29am

SNA

as low as

^$74

Detroit, US (DTT) - Santa Ana, US (SNA)

Aug 30

11:21am

DTW

8h 14m

LAS

Aug 30

7:35pm

SNA

as low as

^$109

Detroit, US (DTT) - Santa Ana, US (SNA)

Aug 13

7:15am

DTW

3h 56m

DEN

Aug 13

11:11am

SNA

as low as

^$151

Detroit, US (DTT) - Santa Ana, US (SNA)

Alaska Airlines

Sep 3

6:30am

DTW

7h 47m

SEA

Sep 3

2:17pm

SNA

as low as

^$159

Detroit, US (DTT) - Santa Ana, US (SNA)

Hawaiian Airlines

Sep 10

6:30am

DTW

7h 47m

SEA

Sep 10

2:17pm

SNA

as low as

^$159

Detroit, US (DTT) - Santa Ana, US (SNA)

Aug 9

8:30am

DTW

3h 47m

PHX

Aug 9

12:17pm

SNA

as low as

^$202

Detroit, US (DTT) - Santa Ana, US (SNA)

Hawaiian Airlines

Sep 9

6:30am

DTW

10h 30m

SEA

SFO

Sep 9

5:00pm

SNA

as low as

^$212

Detroit, US (DTT) - Santa Ana, US (SNA)

Alaska Airlines

Sep 9

7:00am

DTW

11h 31m

ORD

SEA

Sep 9

6:31pm

SNA

as low as

^$214

Detroit, US (DTT) - Santa Ana, US (SNA)

Sep 3

6:30am

DTW

7h 47m

SEA

Sep 3

2:17pm

SNA

as low as

^$261

Detroit, US (DTT) - Santa Ana, US (SNA)

American Airlines

Aug 12

8:00am

DTW

7h 29m

PHX

Aug 12

3:29pm

SNA

as low as

^$262

Detroit, US (DTT) - Santa Ana, US (SNA)

American Airlines

Oct 10

1:37pm

DTW

6h 40m

CLT

Oct 10

8:17pm

SNA

as low as

^$303

Detroit, US (DTT) - Santa Ana, US (SNA)

American Airlines

Nov 12

5:51pm

DTW

4h 21m

DFW

Nov 12

10:12pm

SNA

as low as

^$303

Frequently Asked Questions

What is the cheapest and fastest flight from Detroit to Santa Ana?

The cheapest flight is with American Airlines at $397, taking 4 hours 33 minutes with 1 stop. The fastest flight is with Delta Air Lines at $621, taking 2 hours 9 minutes non-stop.

What are all possible destination arrival airports?

John Wayne Airport-Orange County Airport is the main destination. Possible layover airports include Dallas Fort Worth International Airport, Chicago O'Hare Airport, and Seattle Tacoma International Airport.

What is the time difference between destination and arrival?

The time difference between Detroit and Santa Ana is 2 hours, with Santa Ana being 2 hours behind Detroit.

Is there a direct flight from Detroit to Santa Ana?

Yes, there is a non-stop flight from Detroit Metropolitan Airport to John Wayne Airport-Orange County Airport offered by Delta Air Lines at a price of $621, with a flight time of 2 hours 9 minutes.

Are there convenient layover flights from Detroit to Santa Ana?

Yes, there are convenient layover flights. American Airlines offers a 1-stop flight for $397; United Airlines for $506; Alaska Airlines for $622; and Hawaiian Airlines for $730.

What are the most convenient layover airports for my flight?

The most convenient layover airports for your flight from Detroit to Santa Ana are Dallas Fort Worth International Airport with American Airlines, Chicago O'Hare Airport with United Airlines, and Seattle Tacoma International Airport with Alaska and Hawaiian Airlines.

Flight Deals from Detroit to Santa Ana from $74

Price Drop Deals Near You

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights from Detroit to Santa Ana

Frequently Asked Questions

Flights to Santa Ana