$455 Flight Deals from Detroit to Madrid

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... and +100s more

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Stops

Up to 1 stop
$599
Up to 2 stops
$604

Airlines

Aer Lingus
$1142
Air Europa
$1080
Air France
$667
American Airlines
$786
British Airways
$614
Brussels Airlines
$646
Finnair
$807
IBERIA
$800
Lufthansa
$599
SWISS
$1323
TAP Portugal
$662
Turkish Airlines
$668

Cabin Class

Economy
$599

Departure Airports

Detroit Metropolitan Airport
$599

Arrival Airports

Adolfo Suárez Madrid–Barajas Airport
$599

Layover Airports

Brussels Airport
$646
Charlotte Douglas International Airport
$786
Chicago O Hare Airport
$604
Dallas Fort Worth International Airport
$1121
Dublin Airport
$1142
Frankfurt am Main Airport
$599
General Edward Lawrence Logan International Airport
$662
Humberto Delgado Airport (Lisbon Portela Airport)
$662
Istanbul Airport
$668
London Heathrow Airport
$618
Montreal Trudeau Airport
$630
Munich Airport
$629
New York John F Kennedy Airport
$1080
Newark Liberty Airport
$599
Paris Charles de Gaulle Airport
$667
Philadelphia International Airport
$614
Toronto Pearson Airport
$750
Washington Dulles Airport
$610
Zürich Airport
$1323

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
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BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

Lufthansa

12/01/25

2:20pm

DTW

18h 55m

EWR

12/02/25

9:15am

MAD

Lufthansa

12/10/25

5:55am

MAD

FRA

12/10/25

1:55pm

DTW

^$599

Lufthansa

12/01/25

7:15am

DTW

26h

ORD

EWR

12/02/25

9:15am

MAD

Lufthansa

12/10/25

5:55am

MAD

FRA

12/10/25

1:55pm

DTW

^$604

Lufthansa

11/24/25

7:45pm

DTW

36h 20m

IAD

11/26/25

8:05am

MAD

Lufthansa

12/03/25

5:55am

MAD

FRA

12/03/25

1:55pm

DTW

^$610

British Airways

12/01/25

4:13pm

DTW

16h 42m

PHL

12/02/25

8:55am

MAD

British Airways

12/10/25

1:15pm

MAD

7h 23m

PHL

12/10/25

8:38pm

DTW

^$614

British Airways

11/25/25

3:49pm

DTW

16h 6m

ORD

11/26/25

7:55am

MAD

British Airways

12/04/25

1:15pm

MAD

7h 23m

PHL

12/04/25

8:38pm

DTW

^$614

British Airways

11/25/25

5:32pm

DTW

20h 43m

ORD

LHR

11/26/25

2:15pm

MAD

British Airways

12/04/25

1:15pm

MAD

7h 23m

PHL

12/04/25

8:38pm

DTW

^$618

Lufthansa

12/01/25

2:10pm

DTW

27h 40m

ORD

MUC

12/02/25

5:50pm

MAD

Lufthansa

12/10/25

5:55am

MAD

FRA

12/10/25

1:55pm

DTW

^$629

Lufthansa

11/25/25

4:15pm

DTW

23h 55m

FRA

11/26/25

4:10pm

MAD

Lufthansa

12/04/25

1:35pm

MAD

9h 57m

YUL

ORD

12/04/25

11:32pm

DTW

^$630

British Airways

11/25/25

5:32pm

DTW

20h 43m

ORD

LHR

11/26/25

2:15pm

MAD

British Airways

12/04/25

6:45am

MAD

12h 10m

LHR

ORD

12/04/25

6:55pm

DTW

^$639

Brussels Airlines

11/25/25

4:15pm

DTW

20h 50m

FRA

11/26/25

1:05pm

MAD

Brussels Airlines

12/04/25

6:25am

MAD

10h 42m

BRU

ORD

12/04/25

5:07pm

DTW

^$646

Lufthansa

12/01/25

4:15pm

DTW

25h 35m

FRA

MUC

12/02/25

5:50pm

MAD

Lufthansa

12/10/25

8:35am

MAD

11h 44m

FRA

ORD

12/10/25

8:19pm

DTW

^$659

TAP Portugal

11/25/25

10:25am

DTW

23h 5m

BOS

LIS

11/26/25

9:30am

MAD

TAP Portugal

12/04/25

7:40am

MAD

11h 21m

LIS

BOS

12/04/25

7:01pm

DTW

^$662

Air France

12/01/25

9:20pm

DTW

21h 55m

CDG

12/02/25

7:15pm

MAD

Air France

12/10/25

6:00am

MAD

12h 55m

CDG

12/10/25

6:55pm

DTW

^$667

Turkish Airlines

11/25/25

8:05pm

DTW

27h 25m

IST

11/26/25

11:30pm

MAD

Turkish Airlines

12/04/25

6:20am

MAD

11h 50m

IST

12/04/25

6:10pm

DTW

^$668

Turkish Airlines

12/01/25

8:05pm

DTW

38h 20m

IST

12/03/25

10:25am

MAD

Turkish Airlines

12/10/25

5:55pm

MAD

24h 15m

IST

12/11/25

6:10pm

DTW

^$668

Lufthansa

11/08/25

7:45pm

DTW

36h 20m

IAD

11/10/25

8:05am

MAD

Lufthansa

11/15/25

5:05pm

MAD

20h 50m

FRA

11/16/25

1:55pm

DTW

^$679

Lufthansa

12/06/25

4:15pm

DTW

23h 45m

FRA

12/07/25

4:00pm

MAD

Lufthansa

12/12/25

1:45pm

MAD

27h 51m

FRA

YYZ

12/13/25

5:36pm

DTW

^$750

American Airlines

12/01/25

3:49pm

DTW

16h 6m

ORD

12/02/25

7:55am

MAD

American Airlines

12/10/25

1:00pm

MAD

11h 13m

CLT

12/11/25

12:13am

DTW

^$786

American Airlines

11/25/25

10:36am

DTW

19h 9m

CLT

11/26/25

5:45am

MAD

American Airlines

12/04/25

1:15pm

MAD

7h 23m

PHL

12/04/25

8:38pm

DTW

^$786

IBERIA

11/24/25

3:49pm

DTW

16h 6m

ORD

11/25/25

7:55am

MAD

IBERIA

12/04/25

1:15pm

MAD

7h 23m

PHL

12/04/25

8:38pm

DTW

^$800

IBERIA

11/25/25

10:49am

DTW

21h 6m

ORD

11/26/25

7:55am

MAD

IBERIA

12/04/25

11:35am

MAD

7h 20m

ORD

12/04/25

6:55pm

DTW

^$805

Finnair

11/25/25

8:19am

DTW

21h 26m

CLT

11/26/25

5:45am

MAD

Finnair

12/04/25

1:00pm

MAD

6h 49m

CLT

12/04/25

7:49pm

DTW

^$807

Finnair

12/01/25

4:13pm

DTW

16h 42m

PHL

12/02/25

8:55am

MAD

Finnair

12/10/25

11:35am

MAD

7h 20m

ORD

12/10/25

6:55pm

DTW

^$816

Air France

11/20/25

9:20pm

DTW

18h 5m

CDG

11/21/25

3:25pm

MAD

Air France

11/30/25

5:55pm

MAD

25h

CDG

12/01/25

6:55pm

DTW

^$1010

Air Europa

11/11/25

4:10pm

DTW

19h

JFK

11/12/25

11:10am

MAD

Air Europa

11/15/25

3:35pm

MAD

20h 31m

JFK

11/16/25

12:06pm

DTW

^$1080

Finnair

11/24/25

12:08pm

DTW

17h 37m

CLT

11/25/25

5:45am

MAD

Finnair

11/29/25

1:00pm

MAD

11h 16m

DFW

11/30/25

12:16am

DTW

^$1121

Aer Lingus

12/01/25

5:45am

DTW

28h 15m

PHL

DUB

12/02/25

10:00am

MAD

Aer Lingus

12/10/25

8:40am

MAD

34h 21m

DUB

BOS

12/11/25

7:01pm

DTW

^$1142

British Airways

11/20/25

7:09am

DTW

23h 6m

DFW

11/21/25

6:15am

MAD

British Airways

11/30/25

9:05am

MAD

12h 5m

LHR

ORD

11/30/25

9:10pm

DTW

^$1154

SWISS

11/11/25

2:20pm

DTW

18h 55m

EWR

11/12/25

9:15am

MAD

SWISS

11/15/25

10:10am

MAD

12h 5m

ZRH

ORD

11/15/25

10:15pm

DTW

^$1323

Aer Lingus

11/20/25

11:15am

DTW

22h 45m

PHL

DUB

11/21/25

10:00am

MAD

Aer Lingus

11/30/25

8:40am

MAD

11h 51m

DUB

PHL

11/30/25

8:31pm

DTW

^$1341

Top Deals on flights from Detroit to Madrid

Detroit, US (DTT) - Madrid, ES (MAD)

TAP Portugal

Oct 1

10:50am

DTW

23h 25m

BOS

LIS

Oct 2

10:15am

MAD

as low as

^$455

Detroit, US (DTT) - Madrid, ES (MAD)

British Airways

Sep 23

7:00am

DTW

24h 55m

ORD

Sep 24

7:55am

MAD

as low as

^$456

Detroit, US (DTT) - Madrid, ES (MAD)

Brussels Airlines

Oct 1

4:10pm

DTW

16h 10m

YYZ

Oct 2

8:20am

MAD

as low as

^$459

Detroit, US (DTT) - Madrid, ES (MAD)

Oct 1

5:42pm

DTW

17h 48m

BOS

Oct 2

11:30am

MAD

as low as

^$462

Detroit, US (DTT) - Madrid, ES (MAD)

Aug 10

2:35pm

DTW

17h 30m

IAD

Aug 11

8:05am

MAD

as low as

^$467

Detroit, US (DTT) - Madrid, ES (MAD)

Lufthansa

Sep 23

4:00pm

DTW

24h 15m

FRA

Sep 24

4:15pm

MAD

as low as

^$479

Detroit, US (DTT) - Madrid, ES (MAD)

Aer Lingus

Sep 23

6:00am

DTW

27h 55m

IAD

DUB

Sep 24

9:55am

MAD

as low as

^$511

Detroit, US (DTT) - Madrid, ES (MAD)

American Airlines

Oct 1

11:30am

DTW

23h

CLT

BOS

Oct 2

10:30am

MAD

as low as

^$542

Detroit, US (DTT) - Madrid, ES (MAD)

Finnair

Sep 23

3:02pm

DTW

16h 53m

ORD

Sep 24

7:55am

MAD

as low as

^$552

Detroit, US (DTT) - Madrid, ES (MAD)

IBERIA

Sep 23

7:18pm

DTW

18h 7m

ORD

Sep 24

1:25pm

MAD

as low as

^$556

Detroit, US (DTT) - Madrid, ES (MAD)

Brussels Airlines

Sep 23

1:35pm

DTW

19h 25m

EWR

Sep 24

9:00am

MAD

as low as

^$564

Detroit, US (DTT) - Madrid, ES (MAD)

British Airways

Aug 10

4:00pm

DTW

17h 35m

PHL

Aug 11

9:35am

MAD

as low as

^$581

Frequently Asked Questions

What are all possible destination arrival airports?

The possible destination arrival airport is Adolfo Suárez Madrid–Barajas Airport, with layover airports including Newark Liberty Airport, Chicago O'Hare Airport, Frankfurt am Main Airport, Paris Charles de Gaulle Airport, Istanbul Airport, London Heathrow Airport, and General Edward Lawrence Logan International Airport.

What is the time difference between destination and arrival?

The time difference between Detroit and Madrid is 6 hours, with Madrid ahead of Detroit. Ensure to consider this difference when scheduling your travel plans.

Is there a direct flight from Detroit to Madrid?

There is no direct flight from Detroit to Madrid. The available options include 1 stop flights with Lufthansa at $599 and British Airways at $614, among others.

Are there convenient layover flights from Detroit to Madrid?

Yes, there are convenient layover flights available. The cheapest is with Lufthansa for $599 (1 stop, 18h 55m). British Airways offers a faster option at $614 (1 stop, 16h 6m). Other 1 stop options include Brussels Airlines at $646, Air France at $667, and Turkish Airlines at $668.

What are the most convenient layover airports for the flight?

The most convenient layover airports for your flight from Detroit to Madrid are Newark Liberty, Chicago O'Hare, Frankfurt am Main, Paris Charles de Gaulle, and Istanbul Airport.

What is the cheapest and fastest flight from Detroit to Madrid?

The cheapest flight is with Lufthansa at $599, taking 18 hours 55 minutes. The fastest flight is with British Airways at $614, taking 16 hours 6 minutes.

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Flight Deals from Detroit to Madrid from $455

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights from Detroit to Madrid

Frequently Asked Questions

Flights to Madrid